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Scholar Results 1 - 10 of about 44 citing Poulsen: Impact of Two Common Polymorphisms in the PPARγ Gene on Glucose Tolerance and Plasma.... (0.08 sec) 

PPARγ and human metabolic disease

- nih.gov
RK Semple, VKK Chatterjee, SO' … - Journal of Clinical …, 2006 - Am Soc Clin Investig
The nuclear receptor family of PPARs was named for the ability of the original member to induce
hepatic peroxisome proliferation in mice in response to xenobiotic stimuli. However, studies on
the action and structure of the 3 human PPAR isotypes (PPARα, PPARδ, and PPARγ) ...
Cited by 243 - Related articles - BL Direct - All 10 versions

Peroxisome proliferator-activated receptor-{gamma} calls for activation in …

- endojournals.org
C Knouff, J Auwerx - Endocrine Reviews, 2004 - Endocrine Soc
The peroxisome proliferator-activated receptor (PPAR ) is a prototypical member of the nuclear
receptor superfamily and integrates the control of energy, lipid, and glucose homeostasis. PPAR
can bind a variety of small lipophilic compounds derived from metabolism and nutrition. ...
Cited by 146 - Related articles - All 5 versions

Multifactor-dimensionality reduction shows a two-locus interaction associated with …


YM Cho, MD Ritchie, JH Moore, JY Park, KU Lee, HD … - Diabetologia, 2004 - Springer
Aims/hypothesis. Type 2 diabetes mellitus is a com- plex genetic disease, which results from
interactions between multiple genes and environmental factors without any single factor having
strong independent effects. This study was done to identify gene to gene interactions ...
Cited by 86 - Related articles - BL Direct - All 7 versions

Identification of genes modulated in multiple myeloma using genetically identical …

- bloodjournal.org
NC Munshi, T Hideshima, D Carrasco, M Shammas, D … - Blood, 2004 - Am Soc Hematology
Genetic heterogeneity between individuals confounds the comparison of gene profiling of multiple
myeloma (MM) cells versus normal plasma cells (PCs). To overcome this barrier, we compared
the gene expression profile of CD138 + MM cells from a patient bone marrow (BM) ...
Cited by 73 - Related articles - BL Direct - All 6 versions

Impact of genetic variation of PPARγ in humans


A Meirhaeghe, P Amouyel - Molecular Genetics and Metabolism, 2004 - Elsevier
Peroxisome proliferator-activated receptor γ (PPARγ) is a transcription factor with a key role in
adipocyte differentiation. Since 1997, studies of rare mutations and common polymorphisms
of the PPARγ gene have enabled us to expand our knowledge of the role of this ...
Cited by 65 - Related articles - All 3 versions

[PDF] Differential effects of the C1431T and Pro12Ala PPARgamma gene variants on …


ES Tai, D Corella, M Deurenberg-Yap, X Adiconis, … - The Journal of Lipid …, 2004 - ASBMB
Page 1. Differential effects of the C1431T and Pro12Ala PPARγ gene variants on plasma lipids
and diabetes risk in an Asian population: The 1998 Singapore National Health Survey E Shyong
Tai 1 , Dolores Corella 2,3 , Mabel Deurenberg-Yap 4 , Xian Adiconis 3 , Suok Kai ...
Cited by 49 - Related articles - BL Direct - All 8 versions

Association of Pro12Ala polymorphism in peroxisome proliferator-activated …

- diabetesjournals.org
A Tonjes, M Scholz, M Loeffler, M Stumvoll - Diabetes care, 2006 - Am Diabetes Assoc
RESULTS—In the global comparison, there were no differences in BMI, glucose, insulin, or homeostasis
model assessment of insulin resistance between the Pro/Pro and X/Ala genotype. However,
in the Caucasian subgroup, the X/Ala genotype was associated with significantly ...
Cited by 44 - Related articles - BL Direct - All 4 versions

The human peroxisome proliferator-activated receptor γ2 (PPARγ2) Pro12Ala …


ML Caramori, LH Canani, LA Costa, JL Gross - Diabetes, 2003 - Am Diabetes Assoc
The peroxisome proliferator-activated receptor γ2 (PPARγ2) Pro12Ala polymorphism has been
associated with a decreased risk of type 2 diabetes and a lower albumin excretion rate
(AER) in patients with established diabetes. We performed a case-control study aiming to ...
Cited by 44 - Related articles - BL Direct - All 4 versions

PPAR and human metabolic disease


RK Semple, VKK Chatterjee, SO'Rahilly - 临床调查学报, 2006 - journal.shouxi.net
The nuclear receptor family of PPARs was named for the ability of the original member to induce
hepatic peroxisome proliferation in mice in response to xenobiotic stimuli. However, studies on
the action and structure of the 3 human PPAR isotypes (PPAR, PPAR, and PPAR) ...
Cited by 37 - Related articles - Cached - All 2 versions

Metabolic and genetic influence on glucose metabolism in type 2 diabetic subjects …


H Beck-Nielsen, A Vaag, P Poulsen, M Gaster - Best Practice & Research …, 2003 - Elsevier
Based on our investigations in first-degree relatives, in twins in general, and in monozygotic
twins discordant for type 2 diabetes, we have studied the inheritance of glucose intolerance,
insulin resistance and insulin secretion in order to evaluate the role of genes versus ...
Cited by 35 - Related articles - All 6 versions


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