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Scholar Results 1 - 10 of about 65 citing Beilhack: Purified allogeneic hematopoietic stem cell transplantation blocks diabetes pathogenesi.... (0.22 sec) 

B IOLOGY OF H EMATOPOIETIC S TEM C ELLS AND P ROGENITORS: Implications for …

- spinesmithusa.com [PDF] 
M Kondo, AJ Wagers, MG Manz, SS Prohaska, … - Annual review of immunology, 2003 - Annual Reviews
▪ Abstract Stem cell biology is scientifically, clinically, and politically a
current topic. The hematopoietic stem cell, the common ancestor of all types of
blood cells, is one of the best-characterized stem cells in the body and ...
Cited by 420 - Related articles - BL Direct - All 9 versions

Hematopoietic stem and progenitor cells: clinical and preclinical regeneration of the …

- ucla.edu [PDF] 
JA Shizuru, RS Negrin, IL Weissman, 2004 - Annual Reviews
A vast literature exists on the biology of blood formation and regeneration
under experimental and clinical conditions. The field of hematopoiesis was
recently advanced by the capacity to purify to homogeneity primitive ...
Cited by 160 - Related articles - All 9 versions

Menin regulates pancreatic islet growth by promoting histone methylation and expression …

- pnas.org
SK Karnik, CM Hughes, X Gu, O Rozenblatt- … - Proceedings of the National Academy of Sciences, 2005 - National Acad Sciences
Menin, the product of the Men1 gene mutated in familial multiple endocrine
neoplasia type 1 (MEN1), regulates transcription in differentiated cells. Menin
associates with and modulates the histone methyltransferase activity of a ...
Cited by 99 - Related articles - BL Direct - All 11 versions

The clinical potential of stem cells


EA Mayhall, N Paffett-Lugassy, LI Zon - Current opinion in cell biology, 2004 - Elsevier
Stem cells are defined by their capacity for self-renewal and multilineage
differentiation, making them uniquely situated to treat a broad spectrum of
human diseases. For example, because hematopoietic stem cells can ...
Cited by 64 - Related articles - All 5 versions

Mixed hematopoietic chimerism allows cure of autoimmune diabetes through allogeneic …


B Nikolic, Y Takeuchi, I Leykin, Y Fudaba, RN … - Diabetes, 2004 - Am Diabetes Assoc
Bone marrow transplantation from diabetes-resistant strains with complete
replacement of the recipient immune system by the allogeneic donor has led to
tolerance to donor islets and cure of diabetes in a mouse model of type 1 ...
Cited by 56 - Related articles - BL Direct - All 4 versions

Prevention of type 1 diabetes by gene therapy

- nih.gov
C Tian, J Bagley, N Cretin, N Seth, KW … - Journal of Clinical Investigation, 2004 - Am Soc Clin Investig
The autoimmune disease type 1 diabetes in humans and NOD mice is determined by
multiple genetic factors, among the strongest of which is the inheritance of
diabetes-permissive MHC class II alleles associated with susceptibility to ...
Cited by 54 - Related articles - BL Direct - All 12 versions

Stem cell research: paths to cancer therapies and regenerative medicine

- fsk.it [PDF] 
I Weissman - Jama, 2005 - Am Med Assoc
Most tissues in complex metazoans contain a rare subset of cells that, at the
single-cell level, can self-renew and also give rise to mature daughter cells.
Such stem cells likely in development build tissues and are retained in ...
Cited by 56 - Related articles - BL Direct - All 4 versions

Hematopoiesis from embryonic stem cells: lessons from and for ontogeny

- umn.edu [PDF] 
M Kyba, GQ Daley - Experimental hematology, 2003 - Elsevier
Cellular therapies derived from embryonic stem (ES) cells have acquired new
interest and urgency with the demonstration that embryonic stem cells can be
established from human blastocyst-stage embryos. Our ability to derive ...
Cited by 47 - Related articles - All 8 versions

Donor CD8+ T cells facilitate induction of chimerism and tolerance without GVHD in …

- hematologylibrary.org
Y Liang, T Huang, C Zhang, I Todorov, M … - Blood, 2005 - bloodjournal.hematologylibrary.org
Prevention of autoimmune diabetes and induction of islet transplantation
tolerance in nonobese diabetic (NOD) mice can be reached by induction of mixed
chimerism via bone marrow transplantation (BMT), but this procedure ...
Cited by 34 - Related articles - All 6 versions

Hematopoietic stem cell transplantation prevents diabetes in NOD mice but does not contribute …


EM Kang, PP Zickler, S Burns, SM Langemeijer … - Experimental hematology, 2005 - Elsevier
The treatment of type I diabetes by islet cell transplantation, while promising,
remains restricted due to the incomplete efficacy and toxicity associated with
current immunosuppression, and by limited organ availability. Given reports ...
Cited by 34 - Related articles - All 11 versions


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