E Kroon, LA Martinson, K Kadoya, AG Bang, OG … - Nature …, 2008 - novocell.com Development of a cell therapy for diabetes would be greatly aided by a renewable supply of
human ß-cells. Here we show that pancreatic endoderm derived from human embryonic stem
(hES) cells efficiently generates glucose-responsive endocrine cells after implantation ... Cited by 134 - Related articles - View as HTML - BL Direct - All 10 versions
Y Hori, X Gu, X Xie, SK Kim - PLoS Medicine, 2005 - medicine.plosjournals.org Here we show that brain-derived human neural progenitor cells, exposed to a series of signals
that regulate in vivo pancreatic islet development, form clusters of glucose-responsive
insulin-producing cells (IPCs). During in vitro differentiation of neural progenitor cells with ... Cited by 67 - Related articles - Cached - BL Direct - All 13 versions
- ►endojournals.org MC Jorgensen, J Ahnfelt-Ronne, J Hald, OD … - Endocrine …, 2007 - Endocrine Soc Pancreas morphogenesis and cell differentiation are highly conserved among vertebrates during
fetal development. The pancreas develops through simple budlike structures on the primitive
gut tube to a highly branched organ containing many specialized cell types. This review ... Cited by 37 - Related articles - BL Direct - All 3 versions
D Segara, AV Biankin, JG Kench, CC Langusch, AC … - Clinical Cancer Research, 2005 - AACR Results: We identified aberrant expression of several components of the retinoic acid (RA) signaling
pathway (RARα, MUC4, Id-1, MMP9, uPAR, HB-EGF, HOXB6, and HOXB2), many of which are
known to be aberrantly expressed in pancreatic cancer and PanIN. HOXB2, a ... Cited by 25 - Related articles - All 4 versions
WW Minuth, L Denk, S Heber - Biomaterials, 2005 - Elsevier The construction of an artificial kidney module by tissue engineering or the application of
cell-based therapies for the treatment of renal failure requires exact information regarding the
cellbiological mechanisms of parenchyme development in combination with different ... Cited by 12 - Related articles - All 5 versions
HB Everts, JP Sundberg, DE Ong - Experimental cell research, 2005 - Elsevier Vitamin A deficiency leads to focal metaplasia of numerous epithelial tissues with altered differentiation
from columnar (in general) to stratified squamous cells. This process can be reversed with vitamin
A repletion. Previously, we described a system of retinoic acid (RA) synthesis in the ... Cited by 10 - Related articles - All 3 versions
CN Shen, A Marguerie, CY Chien, C … - Differentiation; …, 2007 - pubmedcentral.nih.gov Recent evidence has shown that retinoic acid (RA) signalling is required for early pancreatic
development in zebrafish and frog but its role in later development in mammals is less clear
cut. In the present study, we determined the effects of RA on the differentiation of the ... Cited by 6 - Related articles - BL Direct - All 9 versions
PV Lear, NVG Jayanthi, WJ Teague, PRV … - Organogenesis, 2004 - pubmedcentral.nih.gov Current interest in the potential use of pancreatic stem-cells in the treatment of insulin dependent
diabetes mellitus has led to increased research into normal pancreatic development. Pancreatic
organogenesis involves branching morphogenesis of undifferentiated epithelium within ... Cited by 4 - Related articles - BL Direct - All 4 versions
M Öström, KA Loffler, S Edfalk, L Selander, U Dahl, … - PLoS One, 2008 - pubmedcentral.nih.gov The identification of secreted factors that can selectively stimulate the generation of insulin producing
β-cells from stem and/or progenitor cells represent a significant step in the development of stem
cell-based β-cell replacement therapy. By elucidating the molecular mechanisms that ... Cited by 4 - Related articles - All 7 versions
J Qin, JM Suh, BJ Kim, CT Yu, T Tanaka, T … - Developmental …, 2007 - interscience.wiley.com The cerebellum is essential for fine control of movement and posture, and it has been a useful
model for studying many aspects of neural development because of its relatively simple anatomy
and developmental program. However, the roles of nuclear receptors (NRs) underlying ... Cited by 4 - Related articles - BL Direct - All 3 versions
