RM Seaberg, SR Smukler, TJ Kieffer, G … - Nature Biotechnology, 2004 - utoronto.ca The clonal isolation of putative adult pancreatic precursors has been an elusive
goal of researchers seeking to develop cell replacement strategies for diabetes.
We report the clonal identification of multipotent precursor cells from the ... Cited by 263 - Related articles - BL Direct - All 13 versions
- ►alphamedpress.org H Segev, B Fishman, A Ziskind, M Shulman, J … - Stem Cells, 2004 - AlphaMed Press The protocol consisted of several steps. Embryoid bodies were first cultured and
plated in insulin-transferrin-selenium-fibronectin medium, followed by medium
supplemented with N2, B27, and basic fibroblast growth factor (bFGF). Next, ... Cited by 216 - Related articles - BL Direct - All 7 versions
S Sipione, A Eshpeter, JG Lyon, GS Korbutt, … - Diabetologia, 2004 - Springer Aim/hypothesis. Embryonic stem (ES) cells have been proposed as a potential
source of tissue for transplan- tation for the treatment of Type 1 diabetes.
However, studies showing differentiation of beta cells from ES cells are ... Cited by 123 - Related articles - BL Direct - All 6 versions
- ►ucsd.edu [PDF] E Hao, B Tyrberg, P Itkin-Ansari, JR Lakey, … - Nature medicine, 2006 - medscape.com The nature and even existence of adult pancreatic endocrine stem or progenitor
cells is a subject of controversy in the field of beta-cell replacement for
diabetes. One place to search for such cells is in the nonendocrine ... Cited by 103 - Related articles - BL Direct - All 11 versions
P Blyszczuk, C Asbrand, A Rozzo, G Kania, … - Int J Dev Biol, 2004 - ijdb.ehu.es ABSTRACT We present a new strategy for the differentiation of embryonic stem
(ES) cells into insulin-producing cells via a multi-step process without
selection and induction of nestin-positive cells. During ES cell ... Cited by 66 - Related articles - View as HTML - All 6 versions
L Zhang, TP Hong, J Hu, YN Liu, YH Wu, LS … - World J Gastroenterol, 2005 - wjgnet.com Results: (1) The monolayer epithelium-like cells had highly proliferative
potential and could be passaged more than 16 times in vitro; (2) RT-PCR analysis
and immunofluorescence stain showed that these cells expressed both nestin ... Cited by 36 - Related articles - Cached - All 8 versions
M Eberhardt, P Salmon, MA von Mach, JG … - Biochemical and Biophysical Research …, 2006 - Elsevier Mesenchymal cells in the developing pancreas express the neural stem cell marker
nestin and the transcription factor islet-1 (Isl-1). Using defined culture
conditions we isolated on a single cell basis nestin producing cells from ... Cited by 35 - Related articles - All 5 versions
- ►alphamedpress.org Y Choi, M Ta, F Atouf, N Lumelsky - Stem Cells, 2004 - AlphaMed Press Strategies designed to produce functional cells from stem cells or from mature
cells hold great promise for treatment of different cell-degenerative diseases.
Type 1 and type 2 diabetes are examples of such diseases. Although ... Cited by 34 - Related articles - BL Direct - All 7 versions
KD Linning, MH Tai, BV Madhukar, CC Chang, … - Pancreas, 2004 - journals.lww.com Objectives: The limited availability of transplantable human islets has
stimulated the development of methods needed to isolate adult pancreatic
stem/progenitor cells capable of self-renewal and endo- crine ... Cited by 35 - Related articles - All 3 versions
- ►endojournals.org O Krylyshkina, J Chen, L Mebis, C Denef, H … - Endocrinology, 2005 - Endocrine Soc Nestin is an intermediate filament protein that has originally been identified
as a marker of neuroepithelial stem/progenitor cells. The present study explored
whether nestin immunoreactivity (nestin-ir) is present in the rat pituitary ... Cited by 31 - Related articles - All 7 versions