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Scholar Results 1 - 10 of about 16 citing Kamp: Sulfonylureas rapidly cross phospholipid bilayer membranes by a free-diffusion mechanism. (0.09 sec) 

Insulin secretagogues, sulfonylurea receptors and KATP channels


J Bryan, A Crane, WH Vila-Carriles, AP … - Current pharmaceutical design, 2005 - ingentaconnect.com
Abstract: ATP-sensitive K + channels, termed K ATP channels, provide a link
between cellular metabolism and membrane electrical activity in a variety of
tissues. Channel isoforms have been identified and are targets for ...
Cited by 38 - Related articles - BL Direct - All 4 versions

Glibenclamide stimulates fluid secretion in rodent cholangiocytes through a cystic …


C Spirlì, R Fiorotto, L Song, J Santos-Sacchi … - Gastroenterology, 2005 - Elsevier
Background & Aims: Progressive liver disease is a severe complication of cystic
fibrosis, a genetic disease characterized by impaired epithelial adenosine
3′,5′-cyclic monophosphate-dependent secretion caused by mutations in ...
Cited by 12 - Related articles - All 16 versions

Imaging Docking and Fusion of Insulin Granules Induced by Antidiabetes Agents

- diabetesjournals.org
S Nagamatsu, M Ohara-Imaizumi, Y Nakamichi, … - Diabetes, 2006 - Am Diabetes Assoc
Sulfonylurea and glinide drugs, commonly used for antidiabetes therapies, are
known to stimulate insulin release from pancreatic β-cells by closing
ATP-sensitive K + channels. However, the specific actions of these drugs on ...
Cited by 5 - Related articles - BL Direct - All 5 versions

Actions of glucagon-like peptide-1 on KATP channel-dependent and-independent effects of …

- endocrinology-journals.org
NH McClenaghan, PR Flatt, AJ Ball - Journal of Endocrinology, 2006 - Soc Endocrinology
This study examined the effects of glucagon-like peptide-1 (GLP-1) on insulin
secretion alone and in combination with sulphonylureas or nateglinide, with
particular attention to K ATP channel-independent insulin secretion. In ...
Cited by 4 - Related articles - BL Direct - All 3 versions

Glibenclamide Treatment Recruits β-Cell Subpopulation Into Elevated and Sustained Basal …

- diabetesjournals.org
Z Ling, Q Wang, G Stangé… - Diabetes, 2006 - Am Diabetes Assoc
Use of sulfonylureas in diabetes treatment is based on their insulin-releasing
effect on pancreatic β-cells. Prolonged action is known to degranulate
β-cells, but functional consequences have not been examined at the ...
Cited by 2 - Related articles - BL Direct - All 5 versions

[PDF] Formulation Affects the Rate of Membrane Degradation Catalyzed by Cationic Amphiphilic …


DR Casey, SC Sebai, GC Shearman, O Ces, … - Industrial and Engineering Chemistry Research, 2008 - imperial.ac.uk
Page 1. Formulation Affects the Rate of Membrane Degradation Catalyzed by
Cationic Amphiphilic Drugs Duncan R. Casey,† Sarra C. Sebai ...
Cited by 2 - Related articles - View as HTML - All 6 versions

Investigation of the effects of sulfonylurea exposure on pancreatic beta cell metabolism


L Brennan, C Hewage, JP Malthouse, NH … - FEBS JOURNAL, 2006 - interscience.wiley.com
Prolonged exposure of pancreatic beta cells to the sulfonylureas glibencamide
and tolbutamide induces subsequent desensitization to the actions of these
drugs. The precise mechanisms underlying this desensitization remain ...
Cited by 1 - Related articles - BL Direct - All 4 versions

[PDF] PROTEIN PHOSPHORYLATION CASCADES REGULATING ISLET β-CELL INSULIN …


M Lehtihet - polopoly9.it.ki.se
Page 1. From the Department of Internal Medicine, The Endocrine and Diabetes Unit
Karolinska Institutet, Stockholm South Hospital, Stockholm, Sweden ...
Related articles - All 8 versions

[PDF] COMBINING SYSTEMS BIOLOGY WITH PHYSIOLOGICALLY BASED …


M von Kleist, C Kloft, W Huisinga - hamilton.ie
Abstract: To increase the efficiency of drug discovery and development,
modelling and simulation in pharmacokinetics and disease is gaining increasing
attraction. Due to recent advances in physiologically based ...
Related articles - All 2 versions

[PDF] Sulfonylurea and Glinide Drugs Preferentially Mediate the Fusion of Newcomer, but Not …


S Nagamatsu, M Ohara-Imaizumi, Y Nakamichi, … - DIABETES, 2006 - Am Diabetes Assoc
Page 1. Original Article Imaging Docking and Fusion of Insulin Granules Induced
by Antidiabetes Agents Sulfonylurea and Glinide Drugs Preferentially Mediate the ...
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