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Scholar Results 1 - 10 of about 58 citing Minami: Increased insulin sensitivity and hypoinsulinemia in APS knockout mice. (0.14 sec) 

Turning signals on and off: GLUT 4 traffic in the insulin-signaling highway

- physiology.org
FSL Thong, CB Dugani, A Klip - Physiology, 2005 - cat.inist.fr
Insulin stimulation of glucose uptake into skeletal muscle and adipose tissues
is achieved by accelerating glucose transporter GLUT 4 exocytosis from
intracellular compartments to the plasma membrane and minimally reducingits ...
Cited by 79 - Related articles - BL Direct - All 4 versions

RNAi-based analysis of CAP, Cbl, and CrkII function in the regulation of GLUT4 by insulin

- jbc.org
P Mitra, X Zheng, MP Czech - Journal of Biological Chemistry, 2004 - ASBMB
Stimulation of glucose transport by insulin in cultured adipocytes through
translocation of intracellular GLUT4 glucose transporters to the plasma membrane
has been suggested to require phosphatidylinositol (PI) 3-kinase-dependent ...
Cited by 67 - Related articles - BL Direct - All 8 versions

The Cbl family proteins: ring leaders in regulation of cell signaling


G Swaminathan, AY Tsygankov - Journal of cellular physiology, 2006 - interscience.wiley.com
It is also possible that your web browser is not configured or not able to
display style sheets. In this case, although the visual presentation will be
degraded, the site should continue to be functional. We recommend using the ...
Cited by 62 - Related articles - BL Direct - All 5 versions

Role of protein kinase B in insulin-regulated glucose uptake


G Welsh, I Hers, D Berwick, G Dell, M Wherlock … - Biochemical Society Transactions, 2005 - bst.portlandpress.com
The activation of protein kinase B (or Akt) plays a central role in the
stimulation of glucose uptake by insulin. Currently, however, numerous questions
remain unanswered regarding the role of this kinase in bringing about this ...
Cited by 55 - Related articles - Cached - All 8 versions

Influence of the crosstalk between growth hormone and insulin signalling on the modulation of …


FP Dominici, DP Argentino, MC Muñoz, JG … - Growth hormone & IGF research, 2005 - Elsevier
Growth hormone (GH) is an important modulator of insulin sensitivity. Multiple
mechanisms appear to be involved in this modulatory effect. GH does not interact
directly with the insulin receptor (IR), but conditions of GH excess are ...
Cited by 55 - Related articles - All 4 versions

The human and mouse complement of SH2 domain proteins—establishing the boundaries of …

- cell.com
BA Liu, K Jablonowski, M Raina, M Arcé, T … - Molecular Cell, 2006 - Elsevier
SH2 domains are interaction modules uniquely dedicated to the recognition of
phosphotyrosine sites and are embedded in proteins that couple protein-tyrosine
kinases to intracellular signaling pathways. Here, we report a ...
Cited by 47 - Related articles - All 20 versions

Primary and essential role of the adaptor protein APS for recruitment of both c-Cbl and its …


MY Ahn, KD Katsanakis, F Bheda, TS Pillay - Journal of Biological Chemistry, 2004 - ASBMB
APS (adapter protein with Pleckstrin homology and Src homology 2 domains) is
recruited by the autophosphorylated insulin receptor and is essential for Glut4
translocation. Although both APS and CAP (c-Cbl-associated protein) ...
Cited by 42 - Related articles - BL Direct - All 4 versions

Disruption of the SH2-B gene causes age-dependent insulin resistance and glucose …

- nih.gov
C Duan, H Yang, MF White, L Rui - Molecular and Cellular Biology, 2004 - Am Soc Microbiol
Insulin regulates glucose homeostasis by binding and activating the insulin
receptor, and defects in insulin responses (insulin resistance) induce type 2
diabetes. SH2-B, an Src homology 2 (SH2) and pleckstrin homology domain- ...
Cited by 38 - Related articles - BL Direct - All 7 versions

Grb10 and Grb14: enigmatic regulators of insulin action–and more?


LJ Holt, K Siddle - Biochemical Journal, 2005 - pubmedcentral.nih.gov
The Grb proteins (growth factor receptor-bound proteins) Grb7, Grb10 and Grb14
constitute a family of structurally related multidomain adapters with diverse
cellular functions. Grb10 and Grb14, in particular, have been implicated in ...
Cited by 39 - Related articles - All 6 versions

c-Cbl–deficient mice have reduced adiposity, higher energy expenditure, and improved …

- nih.gov
JC Molero, TE Jensen, PC Withers, M … - Journal of Clinical Investigation, 2004 - Am Soc Clin Investig
Casitas b-lineage lymphoma (c-Cbl) is an E3 ubiquitin ligase that has an
important role in regulating the degradation of cell surface receptors. In the
present study we have examined the role of c-Cbl in whole-body energy ...
Cited by 32 - Related articles - BL Direct - All 10 versions


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