- ►diabetesjournals.org C Pihoker, LK Gilliam, CS Hampe, Å Lernmark - Diabetes, 2005 - Am Diabetes Assoc Islet cell autoantibodies are strongly associated with the development of type 1 diabetes. The
appearance of autoantibodies to one or several of the autoantigens—GAD65, IA-2, or
insulin—signals an autoimmune pathogenesis of β-cell killing. A β-cell attack may be best ... Cited by 53 - Related articles - BL Direct - All 6 versions
JP Palmer, CS Hampe, H Chiu, A Goel, BM Brooks- … - Diabetes, 2005 - Am Diabetes Assoc Diabetes is classified clinically into two types: type 1 and type 2 diabetes. Type 1 diabetes is
an autoimmune diabetes, whereas, in contrast, type 2 diabetes is nonautoimmune.
However, there is a group of phenotypic adult type 2 diabetic patients (∼10%) who have ... Cited by 40 - Related articles - BL Direct - All 5 versions
M Schlosser, JP Banga, AM Madec, KA Binder, M … - Diabetologia, 2005 - Springer Abstract Aims/hypothesis: Progression to type 1 diabetes is associated with intramolecular epitope
spreading to dis- ease-specific antibody epitopes located in the middle re- gion of glutamic acid
decarboxylase 65 (GAD65). Methods: The relationship between intramolecular epitope ... Cited by 33 - Related articles - All 3 versions
- ►jimmunol.org R Raju, J Foote, JP Banga, TR Hall, CJ … - The Journal of …, 2005 - Am Assoc Immnol Autoantibodies to the 65-kDa isoform of glutamate decarboxylase GAD65 (GAD65Ab) are strong
candidates for a pathological role in Stiff-Person syndrome (SPS). We have analyzed the binding
specificity of the GAD65Ab in serum and cerebrospinal fluid (CSF) of 12 patients with SPS ... Cited by 34 - Related articles - BL Direct - All 5 versions
- ►unair.ac.id [PDF] RG Naik, JP Palmer - Reviews in Endocrine & Metabolic Disorders, 2003 - Springer A very large amount of clinical and basic research sup- ports our current understanding that there
are two major types of diabetes, termed type 1 diabetes (T1DM) (previ- ously known as
insulin-dependent diabetes, IDDM) and type 2 diabetes (T2DM) (previously known as ... Cited by 32 - Related articles - BL Direct - All 8 versions
M Desai, CA Cull, VA Horton, MR Christie, E Bonifacio, … - Diabetologia, 2007 - Springer Abstract Aims/hypothesis Latent autoimmune diabetes in adults (LADA) is a slowly progressive
form of autoimmune diabetes, with autoantibodies to islet proteins developing in older patients
who have no immediate requirement for insulin therapy. Markers of its clinical course are ... Cited by 13 - Related articles - BL Direct - All 3 versions
A Casu, M Trucco, M Pietropaolo - The Pediatric Clinics of North America, 2005 - Elsevier Type 1 diabetes mellitus (T1DM) is characterized by the almost complete absence of insulin
secretion, which is secondary to an autoimmune destruction or dysfunction of the insulin-producing
cells of the pancreatic islets of Langerhans. Because T1DM is an autoimmune disease ... Cited by 10 - Related articles - All 16 versions
LK Gilliam, KA Binder, JP Banga, AM … - Clinical and …, 2004 - pubmedcentral.nih.gov Type I diabetes (TID) is an autoimmune disease characterized in part by the presence of autoantibodies
directed against glutamic acid decarboxylase 65 (GAD65), among other pancreatic islet
antigens. We investigated the independent epitope specificities of these GAD65 ... Cited by 9 - Related articles - BL Direct - All 6 versions
KD Schmidt, C Valeri, RDG Leslie - Clinica Chimica Acta, 2005 - Elsevier Autoantibodies can be detected by various methods including immunofluorescence and radioimmunoassays
using disease-specific radiolabelled recombinant autoantigens As recombinant assay have
high-throughput potential, it is now even possible to screen whole populations. Cited by 8 - Related articles - All 3 versions
CJ Padoa, NJ Crowther, JW Thomas, TR … - Clinical and …, 2005 - pubmedcentral.nih.gov Autoantibodies to insulin are often the first autoantibodies detected in young children with type
1 diabetes and can be present before the onset of clinical diabetes. These autoantibodies and
their epitopes are, however, not well characterized. We explored the use of monoclonal ... Cited by 7 - Related articles - All 6 versions
