- ►queensu.ca [PDF] MC Wang, D Bohmann, H Jasper - Cell, 2005 - Elsevier Aging of a eukaryotic organism is affected by its nutrition state and by its
ability to prevent or repair oxidative damage. Consequently, signal transduction
systems that control metabolism and oxidative stress responses influence ... Cited by 144 - Related articles - All 21 versions
- ►endojournals.org R Aikin, D Maysinger, L Rosenberg - Endocrinology, 2004 - Endocrine Soc Therapeutic strategies aimed at the inhibition of specific cell death mechanisms
may increase islet yield and improve cell viability and function after routine
isolation. The aim of the current study was to explore the possibility of ... Cited by 42 - Related articles - BL Direct - All 3 versions
Y Fujinaka, D Sipula, A Garcia-Ocaña, RC … - Diabetes, 2004 - Am Diabetes Assoc Transgenic overexpression of either parathyroid hormone-related peptide (PTHrP)
or mouse placental lactogen type 1 (mPL1) in pancreatic β-cells, using the rat
insulin II promoter (RIP), results in islet hyperplasia either through ... Cited by 28 - Related articles - BL Direct - All 5 versions
A Proteomics - PROTEOMICS-Clinical Applications - interscience.wiley.com The glucose-sensitive insulin-secretion (GSIS) phenotype is relatively unstable
in long-term culture of beta cells. The purpose of this study was to investigate
relative changes in the proteome between glucose-responsive (low passage) ... Cited by 20 - Related articles - BL Direct - All 4 versions
- ►aspetjournals.org T Boutros, E Chevet, P Metrakos - Pharmacological reviews, 2008 - ASPET Mitogen-activated protein kinase dual-specificity phosphatase-1 (also called
MKP-1, DUSP1, ERP, CL100, HVH1, PTPN10, and 3CH134) is a member of the
threonine-tyrosine dual-specificity phosphatases, one of more than 100 ... Cited by 24 - Related articles - All 4 versions
- ►molbiolcell.org MD Short, SM Fox, CF Lam, KR Stenmark, M … - Molecular biology of the cell, 2006 - Am Soc Cell Biol We have previously found that hypoxia stimulates proliferation of vascular
fibroblasts through G i-mediated activation of ERK1/2. Here, we demonstrate that
hypoxia also activates the atypical protein kinase C (PKC ) isozyme and ... Cited by 12 - Related articles - BL Direct - All 4 versions
KJ Chang-Chen, R Mullur, E Bernal-Mizrachi - Reviews in Endocrine & Metabolic Disorders, 2008 - Springer Abstract Type 2 diabetes mellitus is a complex disease characterized by b-cell
failure in the setting of insulin resistance. In early stages of the disease,
pancreatic b-cells adapt to insulin resistance by increasing mass and ... Cited by 12 - Related articles - All 2 versions
T Kosone, H Takagi, S Kakizaki, N Sohara, N … - BMC gastroenterology, 2006 - biomedcentral.com Transforming growth factor α (TGFα) protects against gastric mucosal injury
and facilitates wound healing. However, its overexpression is known to induce
hypertrophic gastropathy resembling Menetrier's disease in transgenic (TG) ... Cited by 9 - Related articles - Cached - All 8 versions
- ►asnjournals.org M Homme, CP Schmitt, O Mehls, F Schaefer - Journal of the American Society of Nephrology, 2004 - Am Soc Nephrol Parathyroid hormone (PTH) dose dependently inhibits growth factor– and
stress-induced osteoblast proliferation via inactivating mitogen-activated
protein kinase (MAPK) signaling pathways. Osteoblasts have recently been ... Cited by 8 - Related articles - BL Direct - All 4 versions
- ►endojournals.org [PDF] R Aikin, D Maysinger, L Rosenberg - Endocrinology, 2004 - Endocrine Soc Page 1. Cross-talk between PI3K/AKT and JNK mediates survival of isolated human
islets Reid Aikin 1,2 , Dusica Maysinger 2 , and Lawrence Rosenberg 1 ... Cited by 8 - Related articles