N Ahmed - Diabetes research and clinical practice, 2005 - Elsevier Diabetes mellitus is a common endocrine disorder characterised by hyperglycaemia and predisposes
to chronic complications affecting the eyes, blood vessels, nerves and kidneys. Hyperglycaemia
has an important role in the pathogenesis of diabetic complications by increasing protein ... Cited by 213 - Related articles - All 10 versions
J Uribarri, W Cai, O Sandu, M Peppa, T … - ANNALS-NEW …, 2005 - interscience.wiley.com Abstract: Advanced glycation end products (AGEs) are a heterogeneous group of compounds
that form continuously in the body. Their rate of endogenous formation is markedly increased
in diabetes mellitus, a condition in which AGEs play a major pathological role. It is also ... Cited by 60 - Related articles - BL Direct - All 5 versions
H Vlassara - ANNALS-NEW YORK ACADEMY OF SCIENCES, 2005 - interscience.wiley.com Abstract: It is believed that intracellular and extracellular advanced glycation (AGEs) or lipoxidation
end products (ALEs), together with dysregulated glucose and lipid metabolism, are important
contributors to oxidant or carbonyl stress, enhanced cellular redox-sensitive transcription ... Cited by 58 - Related articles - BL Direct - All 5 versions
- ►diabetesjournals.org O Sandu, K Song, W Cai, F Zheng, J Uribarri, H … - Diabetes, 2005 - Am Diabetes Assoc Dietary advanced glycosylation end products (AGEs) have been linked to insulin resistance in
db/db (++) mice. To test whether dietary AGEs play a role in the progression of insulin resistance
in normal mice fed high-fat diets, normal C57/BL6 mice were randomly assigned to ... Cited by 47 - Related articles - BL Direct - All 6 versions
- ►cnfindpark.cn M Negrean, A Stirban, B Stratmann, T … - American Journal of …, 2007 - ajcn.cnfindpark.cn Design: Twenty inpatients with T2DM [ (±SEM) age: 55.4 ± 2.2 y; glycated hemoglobin: 8.8 ±
0.5%] were investigated. In a randomized crossover design, the effects of a low-AGE (LAGE)
and high-AGE (HAGE) meal on macrovascular [by flow-mediated dilatation (FMD)] and ... Cited by 50 - Related articles - BL Direct - All 7 versions
M Peppa, J Uribarri, H Vlassara - Current Diabetes Reports, 2004 - Springer Introduction Cardiovascular disease (CVD) is the leading cause of morbidity and mortality not
only in the United States but also worldwide [1]. Atherosclerosis constitutes the main pathologic
substrate of CVD, and through progressive thickening of the intima and plaque formation ... Cited by 47 - Related articles - BL Direct - All 2 versions
- ►diabetesjournals.org AG Huebschmann, JG Regensteiner, H Vlassara, … - Diabetes Care, 2006 - Am Diabetes Assoc The morbidity caused by diabetes has traditionally been classified into macro- and microvascular
complications. Although macrovascular complications have received greater attention, microvascular
complications are unique to diabetes, and hyperglycemia contributes to their ... Cited by 41 - Related articles - All 6 versions
- ►nih.gov J Uribarri, W Cai, M Peppa, S Goodman, L … - … of Gerontology Series …, 2007 - Geron Soc America Background. Oxidative stress (OS) and inflammatory mediators increase with aging. The levels
of advanced glycation endproducts (AGEs), prooxidant factors linked to chronic diseases such
as diabetes, cardiovascular disease, and renal disease, also increase with aging. AGEs ... Cited by 36 - Related articles - BL Direct - All 5 versions
- ►amjpathol.org W Cai, JC He, L Zhu, X Chen, S Wallenstein, GE … - American Journal of …, 2007 - ASIP Aging is accompanied by increased oxidative stress (OS) and accumulation of advanced glycation
end products (AGEs). AGE formation in food is temperature-regulated, and ingestion of nutrients
prepared with excess heat promotes AGE formation, OS, and cardiovascular disease in ... Cited by 30 - Related articles - BL Direct - All 5 versions
H Vlassara, J Uribarri - Reviews in Endocrine & Metabolic Disorders, 2004 - Springer Diabetes and its complications represent an increasing medical problem worldwide [1]. Chronic
hyperglycemia leads to these complications through several intracellular mechanisms including
increased polyol pathway flow, ac- tivation of protein kinase C activity, increased ... Cited by 28 - Related articles - BL Direct - All 3 versions
