- ►nih.gov BN Finck, DP Kelly - Journal of Clinical Investigation, 2006 - Am Soc Clin Investig Members of the nuclear receptor (NR) superfamily relay physiologic and nutritional cues to critical
gene regulatory responses. The molecular links between external stimuli, cellular signaling
events, and NR-mediated transcriptional control are currently being unraveled. New ... Cited by 226 - Related articles - BL Direct - All 9 versions
- ►umich.edu [PDF] Z Arany, H He, J Lin, K Hoyer, C Handschin, O Toka, F … - Cell Metabolism, 2005 - Elsevier Skeletal and cardiac muscle depend on high turnover of ATP made by mitochondria in order
to contract efficiently. The transcriptional coactivator PGC-1α has been shown to function as a
major regulator of mitochondrial biogenesis and respiration in both skeletal and cardiac ... Cited by 134 - Related articles - All 16 versions
AE Civitarese, S Carling, LK Heilbronn, MH … - PLoS …, 2007 - pubmedcentral.nih.gov The current study was undertaken to examine muscle mitochondrial bioenergetics in response
to caloric restriction alone or in combination with exercise in 36 young (36.8 ± 1.0 y), overweight
(body mass index, 27.8 ± 0.7 kg/m 2 ) individuals randomized into one of three groups for ... Cited by 99 - Related articles - All 7 versions
- ►pnas.org M Sandri, J Lin, C Handschin, W Yang, … - Proceedings of the …, 2006 - National Acad Sciences Maintaining muscle size and fiber composition requires contractile activity. Increased activity
stimulates expression of the transcriptional coactivator PGC-1α (peroxisome proliferator-activated
receptor γ coactivator 1α), which promotes fiber-type switching from glycolytic toward ... Cited by 87 - Related articles - All 7 versions
- ►fasebj.org JM Sacheck, JPK Hyatt, A Raffaello, RT Jagoe, RR Roy … - The FASEB Journal, 2007 - FASEB We previously identified a common set of genes, termed atrogenes, whose expression is coordinately
induced or suppressed in muscle during systemic wasting states (fasting, cancer cachexia, renal
failure, diabetes). To determine whether this transcriptional program also functions during ... Cited by 65 - Related articles - BL Direct - All 4 versions
R Cartoni, B Leger, MB Hock, M Praz, A … - The Journal of …, 2005 - Physiological Soc Mitochondrial impairment is hypothesized to contribute to the pathogenesis of insulin
resistance. Mitofusin (Mfn) proteins regulate the biogenesis and maintenance of the mitochondrial
network, and when inactivated, cause a failure in the mitochondrial architecture and ... Cited by 63 - Related articles - BL Direct - All 9 versions
JA Hawley - Diabetes/Metabolism Reviews - interscience.wiley.com During the past half-century, there has been a dramatic increase in the incidence of obesity,
insulin resistance and type 2 diabetes. A hallmark feature of these conditions is impaired glucose
tolerance (IGT). Cross-sectional and retrospective epidemiological studies have provided ... Cited by 63 - Related articles - BL Direct - All 4 versions
- ►physiology.org Y Yang, A Creer, B Jemiolo, S … - Journal of Applied …, 2005 - Am Physiological Soc The aim of this study was to examine the time course activation of select myogenic (MRF4,
Myf5, MyoD, myogenin) and metabolic (CD36, CPT1, HKII, and PDK4) genes after an acute bout
of resistance (RE) or run (Run) exercise. Six RE subjects [25 ± 4 yr (mean ± SD), 74 ± 14 ... Cited by 61 - Related articles - All 9 versions
- ►fasebj.org [PDF] AP Russell, MKC Hesselink, SK Lo, P Schrauwen - The FASEB Journal, 2005 - FASEB The FASEB Journal express article 10.1096/fj.04-3168fje. Published online April 6, 2005. ...
Regulation of metabolic transcriptional co-activators and ... *Clinique Romande de Réadaptation
SUVA Care, Sion, Switzerland; ... Corresponding author: Aaron P. Russell, Clinique ... Cited by 60 - Related articles - All 5 versions
