- ►drclaudiaanrig.com [PDF] RH Eckel, SM Grundy, PZ Zimmet - The Lancet, 2005 - Elsevier The metabolic syndrome is a common metabolic disorder that results from the increasing prevalence
of obesity. The disorder is defined in various ways, but in the near future a new definition(s) will
be applicable worldwide. The pathophysiology seems to be largely attributable to insulin ... Cited by 1569 - Related articles - All 41 versions
- ►ahajournals.org P Dandona, A Aljada, A Chaudhuri, P Mohanty, R Garg - Circulation, 2005 - Am Heart Assoc The original description of the metabolic syndrome by Reaven 1 consisted of obesity, insulin
resistance, hypertension, impaired glucose tolerance or diabetes, hyperinsulinemia and dyslipidemia
characterized by elevated triglyceride, and low HDL concentrations. All of the features ... Cited by 388 - Related articles - All 7 versions
- ►ahajournals.org A Ceriello, E Motz - Arteriosclerosis, thrombosis, and vascular biology, 2004 - Am Heart Assoc Type 2 diabetes is a worldwide increasing disease resulting from the interaction between a subject's
genetic makeup and lifestyle. In genetically predisposed subjects, the combination of excess
caloric intake and reduced physical activity induces a state of insulin resistance. When ... Cited by 388 - Related articles - BL Direct - All 9 versions
- ►ahajournals.org J Kim, M Montagnani, KK Koh, MJ Quon - Circulation, 2006 - Am Heart Assoc Endothelial dysfunction contributes to cardiovascular diseases, including hypertension,
atherosclerosis, and coronary artery disease, which are also characterized by insulin
resistance. Insulin resistance is a hallmark of metabolic disorders, including type 2 ... Cited by 322 - Related articles - All 9 versions
LF Van Gaal, IL Mertens, CE De Block - Nature, 2006 - nature.com Obesity increases the risk of cardiovascular disease and premature death. Adipose tissue releases
a large number of bioactive mediators that influence not only body weight homeostasis but also
insulin resistance — the core feature of type 2 diabetes — as well as alterations in lipids, ... Cited by 261 - Related articles - BL Direct - All 6 versions
- ►ahajournals.org H Ghanim, A Aljada, D Hofmeyer, T Syed, P Mohanty, P … - Circulation, 2004 - Am Heart Assoc Methods and Results— MNC were prepared from fasting blood samples of obese (n=16; body
mass index [BMI]=37.7±5.0 kg/m 2 ) and normal-weight control (n=16; BMI=23.8±1.9 kg/m 2 )
subjects. Nuclear factor B (NF- B) binding to DNA in nuclear extracts was elevated ... Cited by 170 - Related articles - BL Direct - All 8 versions
SE Shoelson, L Herrero, A Naaz - Gastroenterology, 2007 - Elsevier Weight gain and obesity are major risk factors for conditions and diseases ranging from insulin
resistance and type 2 diabetes mellitus to atherosclerosis and the sequelae of nonalcoholic fatty
liver disease. A chronic, subacute state of inflammation often accompanies the ... Cited by 149 - Related articles - All 23 versions
- ►diabetesjournals.org FB Stentz, GE Umpierrez, R Cuervo, AE Kitabchi - Diabetes, 2004 - Am Diabetes Assoc Acute and chronic hyperglycemia are proinflammatory states, but the status of proinflammatory
cytokines and markers of oxidative stress and cardiovascular risks is not known in hyperglycemic
crises of diabetic ketoacidosis (DKA) and nonketotic hyperglycemia (NKH). We studied 20 ... Cited by 133 - Related articles - BL Direct - All 4 versions
D Jay, H Hitomi, KK Griendling - Free Radical Biology and Medicine, 2006 - Elsevier Diabetes diagnoses are increasing at an alarming rate worldwide. The majority of diabetes-related
deaths arise from cardiovascular complications such as myocardial infarction, stroke, and peripheral
vascular disease. Oxidative stress has been demonstrated to be present in animal ... Cited by 110 - Related articles - All 4 versions
- ►ahajournals.org A Ceriello, R Assaloni, R Da Ros, A Maier, L Piconi, L … - Circulation, 2005 - Am Heart Assoc Methods and Results— Twenty type 2 diabetic patients ate 3 different test meals: a high-fat
meal, 75 g glucose alone, and a high-fat meal plus glucose. Glycemia, triglyceridemia, endothelial
function, nitrotyrosine, C-reactive protein, intercellular adhesion molecule-1, and ... Cited by 103 - Related articles - All 10 versions
