- ►jbc.org JM Schattenberg, Y Wang, R Singh, RM Rigoli, MJ … - Journal of Biological …, 2005 - ASBMB Insulin resistance and increased cytochrome P450 2E1 (CYP2E1) expression are both associated
with and mechanistically implicated in the development of nonalcoholic fatty liver disease. Although
currently viewed as distinct factors, insulin resistance and CYP2E1 expression may be ... Cited by 89 - Related articles - All 4 versions
- ►nih.gov K Nagashima, C Lopez, D Donovan, C … - Journal of Clinical …, 2005 - Am Soc Clin Investig Elevated plasma levels of VLDL triglycerides (TGs) are characteristic of patients with type 2 diabetes
mellitus (T2DM) and are associated with increased production rates (PRs) of VLDL TGs and
apoB. Lipoprotein lipase–mediated (LPL-mediated) lipolysis of VLDL TGs may also be ... Cited by 89 - Related articles - All 8 versions
A Xu, MC Lam, KW Chan, Y Wang, J … - Proceedings of the …, 2005 - National Acad Sciences Angiopoietin-like protein 4 (ANGPTL4) is a circulating protein predominantly expressed in adipose
tissue and liver. Several recent studies demonstrated that ANGPTL4 is the target gene of peroxisome
proliferation activators, the agonists of which are widely used as the antidiabetic and lipid- ... Cited by 73 - Related articles - All 12 versions
- ►nih.gov R Gutiérrez-Juárez, A Pocai, C Mulas, H … - Journal of Clinical …, 2006 - Am Soc Clin Investig Stearoyl-CoA desaturase–1 (SCD1) catalyzes the synthesis of monounsaturated fatty acids from
saturated fatty acids. Mice with a targeted disruption of Scd1 gene locus are lean and display
increased insulin sensitivity. To examine whether Scd1 activity is required for the ... Cited by 70 - Related articles - BL Direct - All 7 versions
- ►ouhsc.edu [PDF] X Li, B Monks, Q Ge, MJ Birnbaum - Nature, 2007 - nature.com Type 2 diabetes mellitus, a disease with significant effects on the health and economy of Western
societies, involves disturbances in both lipid and carbohydrate metabolism 1, 2, 3 . In the
insulin-resistant or diabetic state, the liver is unresponsive to the actions of insulin with ... Cited by 58 - Related articles - BL Direct - All 9 versions
M Yamaguchi - International journal of molecular medicine, 2005 - cat.inist.fr Regucalcin was discovered in 1978 as a Ca 2 + -binding protein that does not contain
EF-hand motif of Ca 2 + -binding domain. The name regucalcin was proposed for this
Ca 2 + -binding protein, which can regulate liver cell functions related to Ca 2 ... Cited by 42 - Related articles - All 5 versions
- ►jlr.org D Botolin, Y Wang, B Christian, DB Jump - The Journal of Lipid Research, 2006 - ASBMB Insulin induces and dietary n-3 PUFAs suppress hepatic de novo lipogenesis by controlling
sterol-regulatory element binding protein-1 nuclear abundance (nSREBP-1). Our goal was to
define the mechanisms involved in this regulatory process. Insulin treatment of rat primary ... Cited by 41 - Related articles - BL Direct - All 4 versions
- ►molbiolcell.org X Du, I Kristiana, J Wong, AJ Brown - Molecular biology of the cell, 2006 - Am Soc Cell Biol Akt is a critical regulator of cell growth, proliferation, and survival that is activated by phosphatidylinositol
3-kinase (PI3K). We investigated the effect of PI3K inhibition on activation of sterol regulatory
element binding protein-2 (SREBP-2), a master regulator of cholesterol homeostasis. ... Cited by 39 - Related articles - BL Direct - All 7 versions
- ►diabetesjournals.org Y Ishigaki, H Katagiri, T Yamada, T Ogihara, J Imai, K … - Diabetes, 2005 - Am Diabetes Assoc For examining whether dissipating excess energy in the liver is a possible therapeutic approach
to high-fat diet–induced metabolic disorders, uncoupling protein-1 (UCP1) was expressed in
murine liver using adenoviral vectors in mice with high-fat diet–induced diabetes and ... Cited by 41 - Related articles - All 5 versions
KH Kim, HJ Shin, K Kim, HM Choi, SH Rhee, HB Moon, … - Gastroenterology, 2007 - Elsevier Background & Aims: Hepatic steatosis occurs frequently in patients with chronic hepatitis B virus
(HBV) or chronic hepatitis C virus (HCV) infection. Recently, several studies suggested that steatosis
plays an important role as a cofactor in other liver diseases such as hepatic fibrosis, ... Cited by 28 - Related articles - All 25 versions
