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Scholar Results 1 - 10 of about 60 citing Contreras: Brain death significantly reduces isolated pancreatic islet yields and functionality.... (0.11 sec) 

Differentiation of In Vitro–Modified Human Peripheral Blood Monocytes Into …


M Ruhnke, H Ungefroren, A Nussler, F Martin, M … - Gastroenterology, 2005 - Elsevier
Background & Aims: Adult stem cells provide a promising alternative for the treatment of diabetes
mellitus and end-stage liver diseases. We evaluated the differentiation potential of human peripheral
blood monocytes into hepatocyte-like and pancreatic islet-like cells. Methods: Monocytes ...
Cited by 93 - Related articles - All 10 versions

Strategic opportunities in clinical islet transplantation


J Shapiro… - Transplantation, 2005 - journals.lww.com
We gratefully acknowledge ongoing support from a Clinical Center for Islet Transplantation Grant
from the Juvenile Diabetes Research Foundation, Capital Health and the Province Wide Services
of the Government of Alberta, the Roberts Fund, the North American Foundation for the ...
Cited by 68 - Related articles - BL Direct - All 4 versions

Current status of clinical islet transplantation


O Korsgren, B Nilsson, C Berne, M Felldin, A Foss, R … - Transplantation, 2005 - journals.lww.com
Transplantation. Wolters Kluwer Health Logo. All Issues. ...
Cited by 64 - Related articles - BL Direct - All 5 versions

Activated Protein C Preserves Functional Islet Mass After Intraportal …

- diabetesjournals.org
JL Contreras, C Eckstein, CA Smyth, G Bilbao, M … - Diabetes, 2004 - Am Diabetes Assoc
Clinical studies indicate that significant loss of functional islet mass occurs in the peritransplant
period. Islets are injured as a result of detrimental effects of brain death, pancreas
preservation, islet isolation, hypoxia, hyperglycemia, and immune-mediated events. In ...
Cited by 40 - Related articles - BL Direct - All 4 versions

Cell permeable peptide of JNK inhibitor prevents islet apoptosis immediately after …


H Noguchi, Y Nakai, S Matsumoto, M … - American Journal of …, 2005 - ccmjournal.org
Although application of the Edmonton protocol has markedly improved outcomes for pancreatic
islet transplantation, the insulin independence rate after islet transplantation from one donor
pancreas has proven to remain low. During the isolation process and subsequent clinical ...
Cited by 37 - Related articles - All 7 versions

Advances in pancreatic islet transplantation in humans


SA Nanji, AM Shapiro - Diabetes Obesity and Metabolism, 2006 - interscience.wiley.com
With recent advances in methods of islet isolation and the introduction of more potent and less
diabetogenic immunosuppressive therapies, islet transplantation has progressed from research
to clinical reality. Presently, several international centres have demonstrated successful ...
Cited by 38 - Related articles - BL Direct - All 4 versions

Massive brain injury enhances lung damage in an isolated lung model of ventilator …

- critcaremed.com
J Lopez-Aguilar, A Villagra, F Bernabe, G Murias … - Critical care …, 2005 - journals.lww.com
From Hospital de Sabadell, Institut Universitari Parc Taulí, Universitat Autònoma de
Barcelona, Spain (JL-A, AV, FB, GM, EP, JR, LB); Laboratory of Experimental Surgery. Mútua
Sabadellenca, Fundació, Privada, Sabadell, Spain (JL-A, AV, FB, GM, EP, JR, LB); ...
Cited by 34 - Related articles - All 7 versions

Donor treatment with carbon monoxide can yield islet allograft survival and …

- diabetesjournals.org
H Wang, SS Lee, W Gao, E Czismadia, J McDaid, R … - Diabetes, 2005 - Am Diabetes Assoc
Treatment of animals or certain cells with carbon monoxide (CO), a product of heme degradation
by heme oxygenase-1 (HO-1), has potent anti-inflammatory and antiapoptotic effects that contribute
to the survival of transplanted organs. We report here that inducing HO-1 in, or ...
Cited by 35 - Related articles - All 6 versions

Prospective and challenges of islet transplantation for the therapy of autoimmune …

- ualberta.ca [PDF] 
AN Balamurugan, R Bottino, N Giannoukakis, C … - Pancreas, 2006 - journals.lww.com
Abstract: Pancreatic islet cell transplantation is an attractive treatment of type 1 diabetes
(T1D). The success enhanced by the Edmonton protocol has fostered phenomenal progress
in the field of clinical islet transplantation in the past 5 years, with 1-year rates of insulin ...
Cited by 31 - Related articles - BL Direct - All 4 versions

Achieving and maintaining insulin independence in human islet transplant …


BJ Hering - Transplantation, 2005 - journals.lww.com
For islet transplants to complete the transition from clinical research to clinical care restoration
of insulin independence must be achieved—as with pancreas transplants—with a single
donor. To achieve this critical milestone more consis- tently it will be imperative to pursue ...
Cited by 29 - Related articles - BL Direct - All 6 versions


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