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Scholar Results 1 - 10 of about 13 citing Köhler: On-line monitoring of apoptosis in insulin-secreting cells. (0.12 sec) 

Regulatory T cells reversibly suppress cytotoxic T cell function independent of …

- harvard.edu [PDF] 
TR Mempel, MJ Pittet, K Khazaie, W Weninger, R … - Immunity, 2006 - Elsevier
Mechanisms of dominant tolerance have evolved within the mammalian immune system to prevent
inappropriate immune responses. CD4 + CD25 + regulatory T (T reg ) cells have emerged as
central constituents of this suppressive activity. By using multiphoton intravital microscopy ...
Cited by 133 - Related articles - All 19 versions

Noninvasive in vivo imaging of pancreatic islet cell biology


S Speier, D Nyqvist, O Cabrera, J Yu, RD Molano, A … - Nature Medicine, 2008 - nature.com
Advanced imaging techniques have become a valuable tool in the study of complex biological
processes at the cellular level in biomedical research. Here, we introduce a new technical platform
for noninvasive in vivo fluorescence imaging of pancreatic islets using the anterior ...
Cited by 9 - Related articles - BL Direct - All 3 versions

Real-time monitoring of apoptosis by caspase-3-like protease induced FRET …


F Johan… - Experimental Diabetes Research, 2008 - hindawi.com
Amyloid formation is cytotoxic and can activate the caspase cascade. Here, we monitor
caspase-3-like activity as reduction of fluorescence resonance energy transfer (FRET) using
the contstruct pFRET2-DEVD containing enhanced cyan fluorescent protin (EYFP) linked ...
Cited by 6 - Related articles - Cached - All 8 versions

Intravital imaging of fluorescent markers and FRET probes by DNA tattooing


AD Bins, J van Rheenen, K Jalink, JR Halstead, … - BMC …, 2007 - biomedcentral.com
By DNA tattooing we transfect keratinocytes of living mice with DNA encoding fluorescent
biosensors. Subsequently, the behavior of individual cells expressing these biosensors can be
visualized within hours and using conventional microscopy equipment. Using this "instant ...
Cited by 5 - Related articles - Cached - All 7 versions

A membrane-bound FRET-based caspase sensor for detection of apoptosis using …


B Angres, H Steuer, P Weber, M Wagner, H … - submitted to …, 2008 - interscience.wiley.com
It is also possible that your web browser is not configured or not able to display style sheets.
In this case, although the visual presentation will be degraded, the site should continue to be
functional. We recommend using the latest version of Microsoft or Mozilla web browser to ...
Cited by 3 - Related articles - All 2 versions

Imaging of Pancreatic Beta-Cell Signal-Transduction


M Kohler, D Nyqvist, T Moede, H Wahlstedt, … - … , Endocrine &# 38; …, 2004 - ingentaconnect.com
Martin Köhler 1 , Daniel Nyqvist 1 , Tilo Moede 1 , Helene Wahlstedt 1 , Over Cabrera 2 , Ingo
Leibiger 1 ... 1 The Rolf Luft Center for Diabetes Research, Department of Molecular
Medicine, Karolinska Institutet, Stockholm, Sweden, 2 Diabetes Research Institute, ...
Cited by 2 - Related articles - BL Direct

Suppressor of cytokine signaling-1 inhibits caspase activation and protects from …


II Zaitseva, M Hultcrantz, V Sharoyko, M Flodström- … - Cellular and Molecular Life … - Springer
Abstract Pancreatic beta cell damage caused by pro- inflammatory cytokines interleukin-1b
(IL-1b), interferon- c (IFNc) and tumor necrosis factor-a (TNFa) is a key event in the pathogenesis
of type 1 diabetes. The suppressor of cytokine signaling-1 (SOCS-1) blocks IFNc-induced ...
Related articles - All 2 versions

MEN1 Missense Mutations Impair Sensitization to Apoptosis Induced by Wild-Type …

- ejcho.info [PDF] 
W Bazzi, M Renon, C Vercherat, Z Hamze, A Lacheretz … - Gastroenterology, 2008 - Elsevier
Missense mutations account for 30% of mutations identified in patients with the multiple endocrine
neoplasia type 1 (MEN1) syndrome. They raise several issues: the distinction between pathogenic
mutations and polymorphisms is sometimes difficult and the functional effects of missense ...
Cited by 1 - Related articles - All 3 versions

Noninvasive high-resolution in vivo imaging of cell biology in the anterior chamber …


S Speier, D Nyqvist, M Köhler, A Caicedo, IB Leibiger, … - Nature Protocols, 2008 - nature.com
There is clearly a demand for an experimental platform that enables cell biology to be studied
in intact vascularized and innervated tissue in vivo. This platform should allow observations of
cells noninvasively and longitudinally at single-cell resolution. For this purpose, we use ...
Related articles - All 3 versions

[PDF] In vivo imaging of islet cells and islet revascularization


D Nyqvist - diss.kib.ki.se
Glucose homeostasis depends on the release of insulin from the pancreatic -cell. Impaired insulin
release is a hallmark of diabetes mellitus. The -cells are situated within the endocrine
pancreas, the islets of Langerhans, which are structurally defined microorgans that create ...
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