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Scholar Results 1 - 10 of about 44 citing Biebermann: Autosomal-dominant mode of inheritance of a melanocortin-4 receptor mutation.... (0.09 sec) 

[PDF] The human obesity gene map: the 2005 update


T Rankinen, A Zuberi, YC Chagnon, SJ … - Obesity, 2006 - pbrc.edu
Abstract RANKINEN, TUOMO, AAMIR ZUBERI, YVON C. CHAGNON, S. JOHN WEISNAGEL,
GEORGE ARGYROPOULOS, BRANDON WALTS, LOUIS PE´RUSSE, AND CLAUDE BOUCHARD. The
human obesity gene map: the 2005 update. Obesity. 2006;14: 529–644. This ...
Cited by 332 - Related articles - View as HTML - All 6 versions

[PDF] The human obesity gene map: the 2004 update


L Perusse, T Rankinen, A Zuberi, YC Chagnon … - Obesity research, 2005 - informatik.hu-berlin.de
Abstract PE´ RUSSE, LOUIS, TUOMO RANKINEN, AAMIR ZUBERI, YVON C. CHAGNON, S.
JOHN WEISNAGEL, GEORGE ARGYROPOULOS, BRANDON WALTS, ERIC E. SNYDER, AND CLAUDE
BOUCHARD. The human obesity gene map: the 2004 update. Obes Res. 2005; ...
Cited by 210 - Related articles - View as HTML - All 6 versions

Melanocortin-1 receptor structure and functional regulation


JC Garcia-Borron, BL Sanchez-Laorden, C … - Pigment Cell Research, 2005 - interscience.wiley.com
The melanogenic actions of the melanocortins are mediated by the melanocortin-1
receptor (MC1R). MC1R is a member of the G-protein-coupled receptors (GPCR)
superfamily expressed in cutaneous and hair follicle melanocytes. ...
Cited by 72 - Related articles - BL Direct - All 4 versions

Prevalence of mutations and functional analyses of melanocortin 4 receptor variants …

- endojournals.org
LH Larsen, SM Echwald, TIA Sorensen, T … - Journal of Clinical Endocrinology & Metabolism, 2005 - Endocrine Soc
Mutations in the gene encoding the melanocortin 4 receptor (MC4R) are associated
with the most common monogenic form of obesity. We examined 750 Danish men with
juvenile-onset obesity (body mass index 33.3 ± 2.4 kg/m 2 ) and 706 ...
Cited by 69 - Related articles - All 6 versions

Prevalence, spectrum, and functional characterization of melanocortin-4 receptor gene …

- endojournals.org
A Hinney, T Bettecken, P Tarnow, H Brumm, K … - Journal of Clinical Endocrinology & Metabolism, 2006 - Endocrine Soc
Context: Autosomal dominant inheritance of mutations in the melanocortin-4
receptor gene (MC4R) is currently regarded as the most relevant genetic cause
for extreme obesity and affects 2–4% of extremely obese individuals.
Cited by 63 - Related articles - BL Direct - All 6 versions

Molecular mechanisms of the neural melanocortin receptor dysfunction in severe early onset …

- auburn.edu [PDF] 
YX Tao - Molecular and cellular endocrinology, 2005 - Elsevier
The neural melanocortin receptors, melanocortin-3 and -4 receptors (MC3R and
MC4R), have been shown to regulate different aspects of energy homeostasis in
rodents. Human genetic studies showed that mutations in the MC4R gene are ...
Cited by 51 - Related articles - All 8 versions

MC1R and the response of melanocytes to ultraviolet radiation


F Rouzaud, AL Kadekaro, ZA Abdel-Malek, VJ … - … Research-Fundamental and Molecular Mechanisms of …, 2005 - Elsevier
The constitutive color of our skin plays a dramatic role in our photoprotection
from solar ultraviolet radiation (UVR) that reaches the Earth and in minimizing
DNA damage that gives rise to skin cancer. More than 120 genes have been ...
Cited by 50 - Related articles - All 4 versions

Large quantitative effect of melanocortin-4 receptor gene mutations on body mass index

- bmj.com
A Dempfle, A Hinney, M Heinzel- … - British Medical Journal, 2004 - jmg.bmj.com
The melanocortin-4 receptor gene (MC4R) is involved in central energy
homeostasis and body weight regulation. Both endogenous anorexigenic and
orexigenic ligands bind to the receptor. 1 Under normal conditions, the ...
Cited by 48 - Related articles - BL Direct - All 6 versions

Dimerization of the human melanocortin 1 receptor: functional consequences and dominant- …


BL Sánchez-Laorden, J Sánchez-Más, E … - Journal of Investigative Dermatology, 2006 - nature.com
The melanocortin 1 receptor (MC1R), a G S -protein-coupled receptor (GPCR), is a
key regulator of proliferation and differentiation of epidermal melanocytes, and
a determinant of human skin phototype and cancer risk. Homodimerization has ...
Cited by 40 - Related articles - BL Direct - All 3 versions

Functional analyses of melanocortin-4 receptor mutations identified from patients with …

- endojournals.org
YX Tao, DL Segaloff - Journal of Clinical Endocrinology & Metabolism, 2005 - Endocrine Soc
Objective: We investigated whether MC4R variants identified from obese patients
with binge eating disorder (T11A, F51L, T112M, and M200V) and variants
identified in nonobese (I102T, F202L, and N240S) or obese (I102S, A154D, ...
Cited by 36 - Related articles - BL Direct - All 9 versions


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