- ►endojournals.org T Kadowaki, T Yamauchi - Endocrine Reviews, 2005 - Endocrine Soc Recently, we have cloned adiponectin receptors in the skeletal muscle (AdipoR1) and liver
(AdipoR2), which appear to comprise a novel cell-surface receptor family. We showed that AdipoR1
and AdipoR2 serve as receptors for globular and full-length adiponectin and mediate ... Cited by 634 - Related articles - All 8 versions
M Cnop, PJ Havel, KM Utzschneider, DB Carr, MK … - Diabetologia, 2003 - Springer Aims/hypothesis. Increased intra-abdominal fat is as- sociated with insulin resistance and an
atherogenic li- poprotein profile. Circulating concentrations of adip- onectin, an adipocyte-derived
protein, are decreased with insulin resistance. We investigated the relation- ships ... Cited by 528 - Related articles - BL Direct - All 5 versions
- ►nih.gov T Kadowaki, T Yamauchi, N Kubota, K … - Journal of Clinical …, 2006 - Am Soc Clin Investig Adiponectin is an adipokine that is specifically and abundantly expressed in adipose tissue and
directly sensitizes the body to insulin. Hypoadiponectinemia, caused by interactions of genetic
factors such as SNPs in the Adiponectin gene and environmental factors causing obesity, ... Cited by 411 - Related articles - BL Direct - All 9 versions
Y Qi, N Takahashi, SM Hileman, HR Patel, AH … - Nature …, 2004 - members.medscape.com Adiponectin (ADP) is an adipocyte hormone involved in glucose and lipid metabolism. We detected
a rise in ADP in cerebrospinal fluid after intravenous (iv) injection, consistent with brain
transport. In contrast to leptin, intracerebroventricular (icv) administration of ADP ... Cited by 268 - Related articles - BL Direct - All 14 versions
- ►cell.com L Guarente, F Picard - Cell, 2005 - Elsevier A nutritious diet low in calories improves the health and extends the life span of rodents. Recent
studies identified a gene, SIR2, which encodes an NAD-dependent deacetylase and may mediate
the effects of calorie restriction. In this review, we discuss SIR2 genes and calorie ... Cited by 247 - Related articles - All 19 versions
- ►diabetesjournals.org M Daimon, T Oizumi, T Saitoh, W Kameda, A Hirata, … - Diabetes Care, 2003 - Am Diabetes Assoc RESEARCH DESIGN AND METHODS—The serum levels of adiponectin and tumor necrosis
factor- (TNF- ) at baseline (from 1995 to 1997) were evaluated in 1,792 individuals (1,023 women
and 769 men, aged 58.5 ± 12.5 years) from a cohort population (n = 3,706) of the ... Cited by 233 - Related articles - BL Direct - All 6 versions
- ►jbc.org A Xu, KW Chan, RLC Hoo, Y Wang, KCB Tan, J … - Journal of Biological …, 2005 - ASBMB The antidiabetic hormone adiponectin circulates in blood as several oligomeric complexes, and
the ratios between them are critical in determining insulin sensitivity. In this study we investigated
the role of testosterone in regulating the oligomeric complex distribution of adiponectin. ... Cited by 180 - Related articles - All 5 versions
- ►daegu.ac.kr [PDF] SM Rangwala, MA Lazar - Trends in Pharmacological Sciences, 2004 - Elsevier The peroxisome proliferator-activated receptor γ (PPAR-γ) has been the focus of intense research
during the past decade because ligands for this receptor have emerged as potent insulin sensitizers
used in the treatment of type 2 diabetes. Recent advances include the discovery of novel ... Cited by 173 - Related articles - All 5 versions
- ►alfediam.org [PDF] M Guerre-Millo - Diabetes and Metabolism, 2004 - Elsevier It is now recognized that the white adipose tissue (WAT) produces a variety of bioactive
peptides, collectively termed “adipokines”. Alteration of WAT mass in obesity or lipoatrophy, affects
the production of most adipose secreted factors. Since both conditions are associated ... Cited by 170 - Related articles - BL Direct - All 10 versions
- ►endojournals.org A Bottner, J Kratzsch, G Muller, TM Kapellen, S … - Journal of Clinical …, 2004 - Endocrine Soc Adiponectin is an adipocytokine with profound antidiabetic and antiatherogenic effects that is
decreased in obesity. With the increasing prevalence of obesity and the emergence of related
disorders, including type 2 diabetes in children, the regulation of adiponectin and its ... Cited by 143 - Related articles - BL Direct - All 6 versions