- ►pnas.org Z Hu, SH Cha, S Chohnan, MD Lane - Proceedings of the National Academy of Sciences, 2003 - National Acad Sciences Previous studies showed that ip administration of C75, a potent inhibitor of
fatty acid synthase (FAS), blocked fasting-induced up-regulation of orexigenic
neuropeptides and down-regulation of anorexigenic neuropeptides in the ... Cited by 102 - Related articles - BL Direct - All 10 versions
- ►nutrition.org WJ Fu, TE Haynes, R Kohli, J Hu, W Shi, TE … - Journal of Nutrition, 2005 - Am Soc Nutrition This study was conducted to test the hypothesis that dietary supplementation of
arginine, the physiologic precursor of nitric oxide (NO), reduces fat mass in
the Zucker diabetic fatty (ZDF) rat, a genetically obese animal model of ... Cited by 74 - Related articles - All 5 versions
- ►nih.gov S Gao, KP Kinzig, S Aja, KA Scott, W Keung … - Proceedings of the National Academy of Sciences, 2007 - National Acad Sciences Hypothalamic fatty acid metabolism has recently been implicated in the controls
of food intake and energy homeostasis. We report that intracerebroventricular
(ICV) injection of leptin, concomitant with inhibiting AMP-activated kinase ... Cited by 26 - Related articles - BL Direct - All 8 versions
CV Mobbs, F Isoda, H Makimura, J Mastaitis, … - Physiology & behavior, 2005 - Elsevier Since nutrition-sensitive feedback signals normally act to maintain relatively
stable levels of both available and stored nutritional resources, failure in one
or more of these feedback signals could plausibly lead to obese phenotypes. ... Cited by 22 - Related articles - All 4 versions
WS Dhillo - Thyroid, 2007 - liebertonline.com Obesity is a major public health problem associated with morbidity and mortality
and continues to increase worldwide. This review focuses on the regions of the
brain that are important in appetite regulation and the circulating factors ... Cited by 22 - Related articles - BL Direct - All 5 versions
C Cruciani-Guglielmacci, A Hervalet, L … - Diabetologia, 2004 - Springer Aims/hypothesis. NEFA play a key role in the setting of insulin resistance and
hyperinsulinaemia, which are both features of the prediabetic state. In addition
to the direct effects on pancreas and peripheral tissues, NEFA have been ... Cited by 18 - Related articles - All 3 versions
IW Shu, DL Lindenberg, TM Mizuno, JL … - Brain research, 2003 - Elsevier Hypothalamic POMC neurons mediate catabolic responses such as decreased food
intake and increased energy expenditure by, in part, monitoring levels of
metabolic factors such as glucose, insulin and leptin. Recently, fatty acid ... Cited by 18 - Related articles - All 4 versions
- ►diabetesjournals.org BE Levin, L Kang, NM Sanders, AA Dunn- … - Diabetes, 2006 - Am Diabetes Assoc Glucosensing is a property of specialized neurons in the brain that regulate
their membrane potential and firing rate as a function of ambient glucose
levels. These neurons have several similarities to β- and α-cells in the ... Cited by 17 - Related articles - BL Direct - All 4 versions
X Yang, T Funabashi, LM Kow, CV Mobbs - Glucokinase and glycemic diseases: from basics to …, 2004 - books.google.com Matschinsky FM, Magnuson MA (eds): Glucokinase and Glycemic Disease: From Basics
to Novel Therapeutics. Front Diabetes. Basel, Karger, 2004, vol 16, pp 313-326 A
Glucokinase/AP-1 Glucose Transduction Mechanism in the Ventromedial ... Cited by 10 - Related articles - BL Direct - All 3 versions
- ►physiology.org N Simler, A Grosfeld, A Peinnequin, M Guerre- … - American Journal of Physiology- Endocrinology And …, 2006 - Am Physiological Soc Exposure to hypoxia induces anorexia in humans and rodents, but the role of
leptin remains under discussion and that of orexigenic and anorexigenic
hypothalamic neuropeptides remains unknown. The present study was designed ... Cited by 10 - Related articles - BL Direct - All 4 versions
