- ►cell.com P Arner - Trends in Endocrinology & Metabolism, 2003 - Elsevier Globally, the prevalence of obesity is escalating, and insulin resistance
resulting from increased (predominantly visceral) adipose tissue mass has been
identified as a key factor that could drive parallel rises in type 2 ... Cited by 232 - Related articles - All 11 versions
- ►nih.gov L Wilson-Fritch, S Nicoloro, M Chouinard, MA … - Journal of Clinical Investigation, 2004 - Am Soc Clin Investig Adipose tissue plays a central role in the control of energy homeostasis through
the storage and turnover of triglycerides and through the secretion of factors
that affect satiety and fuel utilization. Agents that enhance insulin ... Cited by 151 - Related articles - BL Direct - All 15 versions
I Bogacka, H Xie, GA Bray, SR Smith - Diabetes, 2005 - Am Diabetes Assoc Thiazolidenediones such as pioglitazone improve insulin sensitivity in diabetic
patients by several mechanisms, including increased uptake and metabolism of
free fatty acids in adipose tissue. The purpose of the present study was to ... Cited by 118 - Related articles - All 5 versions
- ►endojournals.org KM Utzschneider, SE Kahn - Journal of Clinical Endocrinology & Metabolism, 2006 - Endocrine Soc Evidence Synthesis: Insulin resistance in NAFLD is characterized by reductions
in whole-body, hepatic, and adipose tissue insulin sensitivity. The mechanisms
underlying the accumulation of fat in the liver may include excess dietary ... Cited by 114 - Related articles - BL Direct - All 4 versions
V Fonseca - The American journal of medicine, 2003 - Elsevier Treatment of diabetes mellitus with medications, including insulin,
sulfonylureas, and thiazolidinediones (TZDs), often leads to weight gain through
a variety of mechanisms. Weight gain can have adverse consequences for ... Cited by 107 - Related articles - All 8 versions
KC Choi, OH Ryu, KW Lee, HY Kim, JA Seo, … - Biochemical and biophysical research communications, 2005 - Elsevier A variety of adipocytokines and peptides secreted from adipocytes have been
considered to play a crucial role in obesity, insulin resistance, and type 2
diabetes. Recently, visfatin, a new adipocytokine, known as a pre-B cell ... Cited by 94 - Related articles - All 4 versions
MB Snijder, RM Van Dam, M Visser, JC … - International journal of epidemiology, 2006 - IEA Since the 1950s it has been recognized that apart from overall obesity the
distribution of body fat can influence disease risk. 5 In particular an
abdominal fat distribution is associated with metabolic disturbances and ... Cited by 88 - Related articles - BL Direct - All 8 versions
GD Tan, BA Fielding, JM Currie, SM … - Diabetologia, 2005 - Springer Abstract Aims/hypothesis: We investigated the effects of rosiglitazone on NEFA
and triglyceride metabolism in type 2 diabetes. Methods: In a double-blind,
placebo-con- trolled, cross-over study of rosiglitazone in diet-treated ... Cited by 85 - Related articles - All 2 versions
- ►adisonline.com [PDF] M Rendell - Drugs, 2004 - ingentaconnect.com The sulphonylureas act by triggering insulin release from the pancreatic β
cell. Abstract A specific site on the adenosine triphosphate (ATP)-sensitive
potassium channels is occupied by sulphonylureas leading to closure of the ... Cited by 86 - Related articles - BL Direct - All 7 versions
