- ►endojournals.org JW Tomlinson, EA Walker, IJ Bujalska, N … - Endocrine Reviews, 2004 - Endocrine Soc 11ß-Hydroxysteroid dehydrogenase type 1 (11ß-HSD1) interconverts inactive
cortisone and active cortisol. Although bidirectional, in vivo it is believed to
function as a reductase generating active glucocorticoid at a prereceptor ... Cited by 251 - Related articles - BL Direct - All 4 versions
- ►cell.com JP Berger, TE Akiyama, PT Meinke - Trends in Pharmacological Sciences, 2005 - Elsevier The three peroxisome-proliferator-activated receptor (PPAR) subtypes, PPAR-γ,
PPAR-α and PPAR-δ, are nuclear receptors that have been the focus of extensive
research during the past decade. These receptors function as lipid sensors ... Cited by 242 - Related articles - All 6 versions
- ►endojournals.org TP Combs, UB Pajvani, AH Berg, Y Lin, LA … - Endocrinology, 2004 - Endocrine Soc Adiponectin is a plasma protein expressed exclusively in adipose tissue.
Adiponectin levels are linked to insulin sensitivity, but a direct effect of
chronically elevated adiponectin on improved insulin sensitivity has not ... Cited by 203 - Related articles - BL Direct - All 5 versions
- ►nih.gov JY Kim, E van de Wall, M Laplante, A Azzara, … - Journal of Clinical Investigation, 2007 - Am Soc Clin Investig 1 Department of Cell Biology and 2 Department of Medicine, Albert Einstein
College of Medicine, New York, New York, USA. 3 Department of Anatomy and
Physiology, Laval University Hospital Centre Research Centre, Laval ... Cited by 120 - Related articles - BL Direct - All 10 versions
- ►endojournals.org ME Trujillo, PE Scherer - Endocrine reviews, 2006 - Endocrine Soc The endocrine functions of the adipose organ are widely studied at this stage.
The adipose organ, and in particular adipocytes, communicate with almost all
other organs. Although some adipose tissue pads assume the functions as ... Cited by 115 - Related articles - BL Direct - All 9 versions
GD Tan, BA Fielding, JM Currie, SM … - Diabetologia, 2005 - Springer Abstract Aims/hypothesis: We investigated the effects of rosiglitazone on NEFA
and triglyceride metabolism in type 2 diabetes. Methods: In a double-blind,
placebo-con- trolled, cross-over study of rosiglitazone in diet-treated ... Cited by 85 - Related articles - All 2 versions
- ►physiology.org M Kabir, KJ Catalano, S Ananthnarayan, SP … - American Journal of Physiology- Endocrinology And …, 2005 - Am Physiological Soc The mechanism by which increased central adiposity causes hepatic insulin
resistance is unclear. The "portal hypothesis" implicates increased lipolytic
activity in the visceral fat and therefore increased delivery of free fatty ... Cited by 81 - Related articles - All 4 versions
- ►nih.gov YS Tsai, HJ Kim, N Takahashi, HS Kim, JR … - Journal of Clinical Investigation, 2004 - Am Soc Clin Investig Peroxisome proliferator–activated receptor γ (PPARγ), the molecular target
of a class of insulin sensitizers, regulates adipocyte differentiation and lipid
metabolism. A dominant negative P467L mutation in the ligand-binding domain ... Cited by 81 - Related articles - BL Direct - All 10 versions
- ►physiology.org AN Carley, LM Semeniuk, Y Shimoni, E Aasum … - American Journal of Physiology- Endocrinology And …, 2004 - Am Physiological Soc Hearts from insulin-resistant type 2 diabetic db/db mice exhibit features of a
diabetic cardiomyopathy with altered metabolism of exogenous substrates and
reduced contractile performance. Therefore, the effect of chronic oral ... Cited by 59 - Related articles - BL Direct - All 5 versions
- ►nih.gov N Tiffin, E Adie, F Turner, HG Brunner, MA … - Nucleic acids research, 2006 - Oxford Univ Press Genome-wide experimental methods to identify disease genes, such as linkage
analysis and association studies, generate increasingly large candidate gene
sets for which comprehensive empirical analysis is impractical. ... Cited by 47 - Related articles - BL Direct - All 20 versions
