- ►nih.gov SR Farmer - Cell metabolism, 2006 - Elsevier A detailed understanding of the processes governing adipose tissue formation will be instrumental
in combating the obesity epidemic. Much progress has been made in the last two decades in
defining transcriptional events controlling the differentiation of mesenchymal stem cells ... Cited by 140 - Related articles - All 13 versions
JC Hogan, JM Stephens - Diabetes, 2005 - Am Diabetes Assoc Growth hormone (GH) diminishes adipose tissue mass in vivo and decreases expression and
activity of fatty acid synthase (FAS) in adipocytes. GH and prolactin (PRL) are potent activators
of STAT5 and exert adipogenic and antiadipogenic effects in adipocytes. In this study, we ... Cited by 31 - Related articles - All 5 versions
- ►nodak.edu [PDF] TA Kokta, MV Dodson, A Gertler, RA Hill - Domestic Animal Endocrinology, 2004 - Elsevier Adipose and muscle tissues undergo regulated growth and differentiation processes that are
modulated by a wide range of factors. The interactions between myogenic cells and adipocytes
play a significant role in growth and development, including the rate and extent of ... Cited by 31 - Related articles - All 9 versions
- ►endojournals.org CA Shang, MJ Waters - Molecular Endocrinology, 2003 - Endocrine Soc Although it is the best characterized in vitro model of GH action, the mechanisms used by GH
to induce differentiation of murine 3T3-F442A preadipocytes remain unclear. Here we have examined
the role of three transcriptional regulators in adipogenesis. These regulators are either ... Cited by 19 - Related articles - BL Direct - All 4 versions
WC Stewart, JE Baugh, ZE Floyd, JM Stephens - Biochemical and Biophysical …, 2004 - Elsevier The 3T3-L1 cells differentiate into fat cells that have many properties of native adipocytes
including: substantial lipid accumulation, insulin sensitivity, and the ability to secrete endocrine
hormones. A substantial expense in using these cells is fetal bovine serum (FBS), a ... Cited by 19 - Related articles - All 3 versions
- ►jbc.org L Rocha-Viegas, GP Vicent, JL Baranao, M Beato, … - Journal of Biological …, 2006 - ASBMB The bcl-X gene plays a critical role in apoptosis. Six different isoforms generated by tissue-specific
promoter usage and alternative splicing were described. Some of them exert opposite effects
on cell death. In mammary epithelial cells glucocorticoids induce bcl-X expression and ... Cited by 12 - Related articles - All 6 versions
- ►shouxi.net UA White, AA Coulter, TK Miles, JM Stephens - Diabetes, 2007 - Am Diabetes Assoc The purpose of this study was to determine whether pyruvate dehydrogenase kinase (PDK)4
was expressed in adipocytes and whether PDK4 expression was hormonally regulated in fat
cells. Both Northern blot and Western blot analyses were conducted on samples isolated ... Cited by 13 - Related articles - BL Direct - All 5 versions
- ►jimmunol.org R Gonsky, RL Deem, J Bream, HA Young, … - The Journal of …, 2004 - Am Assoc Immnol IFN- is an important immunoregulatory protein with tightly controlled expression in activated T
and NK cells. Three potential STAT binding regions have been recognized within the IFN-
promoter: 1) an IL-12-mediated STAT4 binding site at –236 bp; 2) a newly identified IL-2- ... Cited by 9 - Related articles - BL Direct - All 5 versions
ZE Floyd, G Kilroy, X Wu, JM … - Journal of cellular …, 2007 - interscience.wiley.com Adipocyte function is highly regulated in response to changing oxygen levels and physiological
regulation of adipocyte formation involves factors originally identified as hypoxia-responsive
proteins. Inhibition of adipogenesis at low oxygen tension is associated with activation of ... Cited by 8 - Related articles - BL Direct - All 5 versions