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Scholar Results 1 - 10 of about 29 citing Floyd: STAT5A promotes adipogenesis in nonprecursor cells and associates with the glucocorticoid.... (0.10 sec) 

Transcriptional control of adipocyte formation

- nih.gov
SR Farmer - Cell metabolism, 2006 - Elsevier
A detailed understanding of the processes governing adipose tissue formation will be instrumental
in combating the obesity epidemic. Much progress has been made in the last two decades in
defining transcriptional events controlling the differentiation of mesenchymal stem cells ...
Cited by 140 - Related articles - All 13 versions

The regulation of fatty acid synthase by STAT5A


JC Hogan, JM Stephens - Diabetes, 2005 - Am Diabetes Assoc
Growth hormone (GH) diminishes adipose tissue mass in vivo and decreases expression and
activity of fatty acid synthase (FAS) in adipocytes. GH and prolactin (PRL) are potent activators
of STAT5 and exert adipogenic and antiadipogenic effects in adipocytes. In this study, we ...
Cited by 31 - Related articles - All 5 versions

Intercellular signaling between adipose tissue and muscle tissue

- nodak.edu [PDF] 
TA Kokta, MV Dodson, A Gertler, RA Hill - Domestic Animal Endocrinology, 2004 - Elsevier
Adipose and muscle tissues undergo regulated growth and differentiation processes that are
modulated by a wide range of factors. The interactions between myogenic cells and adipocytes
play a significant role in growth and development, including the rate and extent of ...
Cited by 31 - Related articles - All 9 versions

Decreased expression of adipogenic genes in obese subjects with type 2 diabetes


SG Dubois, LK Heilbronn, SR Smith, JB … - … (Silver Spring, Md.), 2006 - pubmedcentral.nih.gov
We examined the expression of candidate genes involved in adipocyte proliferation and/or differentiation
[CCAAT/enhancer-binding protein (C/EBP) α, C/EBPδ, GATA domain-binding protein 3
(GATA3), C/EBPβ, peroxisome proliferator-activated receptor (PPAR) γ2, signal ...
Cited by 21 - Related articles - All 5 versions

Constitutively active signal transducer and activator of transcription 5 can replace …

- endojournals.org
CA Shang, MJ Waters - Molecular Endocrinology, 2003 - Endocrine Soc
Although it is the best characterized in vitro model of GH action, the mechanisms used by GH
to induce differentiation of murine 3T3-F442A preadipocytes remain unclear. Here we have examined
the role of three transcriptional regulators in adipogenesis. These regulators are either ...
Cited by 19 - Related articles - BL Direct - All 4 versions

STAT 5 activators can replace the requirement of FBS in the adipogenesis of 3T3- …


WC Stewart, JE Baugh, ZE Floyd, JM Stephens - Biochemical and Biophysical …, 2004 - Elsevier
The 3T3-L1 cells differentiate into fat cells that have many properties of native adipocytes
including: substantial lipid accumulation, insulin sensitivity, and the ability to secrete endocrine
hormones. A substantial expense in using these cells is fetal bovine serum (FBS), a ...
Cited by 19 - Related articles - All 3 versions

Glucocorticoids repress bcl-X expression in lymphoid cells by recruiting STAT5B to …

- jbc.org
L Rocha-Viegas, GP Vicent, JL Baranao, M Beato, … - Journal of Biological …, 2006 - ASBMB
The bcl-X gene plays a critical role in apoptosis. Six different isoforms generated by tissue-specific
promoter usage and alternative splicing were described. Some of them exert opposite effects
on cell death. In mammary epithelial cells glucocorticoids induce bcl-X expression and ...
Cited by 12 - Related articles - All 6 versions

The STAT5A-mediated induction of pyruvate dehydrogenase kinase 4 expression …

- shouxi.net
UA White, AA Coulter, TK Miles, JM Stephens - Diabetes, 2007 - Am Diabetes Assoc
The purpose of this study was to determine whether pyruvate dehydrogenase kinase (PDK)4
was expressed in adipocytes and whether PDK4 expression was hormonally regulated in fat
cells. Both Northern blot and Western blot analyses were conducted on samples isolated ...
Cited by 13 - Related articles - BL Direct - All 5 versions

Enhancer Role of STAT5 in CD2 Activation of IFN-{gamma} Gene Expression

- jimmunol.org
R Gonsky, RL Deem, J Bream, HA Young, … - The Journal of …, 2004 - Am Assoc Immnol
IFN- is an important immunoregulatory protein with tightly controlled expression in activated T
and NK cells. Three potential STAT binding regions have been recognized within the IFN-
promoter: 1) an IL-12-mediated STAT4 binding site at –236 bp; 2) a newly identified IL-2- ...
Cited by 9 - Related articles - BL Direct - All 5 versions

Effects of prolyl hydroxylase inhibitors on adipogenesis and hypoxia inducible …


ZE Floyd, G Kilroy, X Wu, JM … - Journal of cellular …, 2007 - interscience.wiley.com
Adipocyte function is highly regulated in response to changing oxygen levels and physiological
regulation of adipocyte formation involves factors originally identified as hypoxia-responsive
proteins. Inhibition of adipogenesis at low oxygen tension is associated with activation of ...
Cited by 8 - Related articles - BL Direct - All 5 versions


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