- ►ahajournals.org LR Peterson, P Herrero, KB Schechtman, SB … - Circulation, 2004 - Am Heart Assoc Methods and Results— We studied 31 young women (body mass index [BMI] 19 to 52
kg/m 2 ); 19 were obese (BMI >30 kg/m 2 ). Myocardial oxygen consumption (M O 2
) and fatty acid uptake (MFAUp), utilization (MFAU), and oxidation (MFAO) ... Cited by 154 - Related articles - All 9 versions
S Boudina, ED Abel - Circulation, 2007 - Am Heart Assoc The prevalence of diabetes mellitus is growing rapidly. It is estimated that
globally the number of adults affected with diabetes will increase from 135
million in 1995 to 300 million by 2025. 1 Patients with diabetes mellitus ... Cited by 140 - Related articles - All 5 versions
PK Mazumder, BT O'Neill, MW Roberts, J … - Diabetes, 2004 - Am Diabetes Assoc Diabetes alters cardiac substrate metabolism. The cardiac phenotype in
insulin-resistant states has not been comprehensively characterized. The goal of
these studies was to determine whether the hearts of leptin-deficient ... Cited by 100 - Related articles - BL Direct - All 6 versions
AN Carley, DL Severson - BBA-Molecular and Cell Biology of Lipids, 2005 - Elsevier The metabolic phenotype of hearts has been investigated using rodent models of
type 2 diabetes which exhibit obesity and insulin resistance: db/db and ob/ob
mice, and Zucker fatty and ZDF rats. In general, cardiac fatty acid (FA) ... Cited by 73 - Related articles - All 3 versions
- ►physiology.org X Shen, S Zheng, V Thongboonkerd, M Xu, WM … - American Journal of Physiology- Endocrinology And …, 2004 - Am Physiological Soc Diabetic cardiomyopathy is a common complication leading to heightened risk of
heart failure and death. In the present report, we performed proteomic analysis
on total cardiac proteins from the OVE26 mouse model of type 1 diabetes to ... Cited by 71 - Related articles - BL Direct - All 4 versions
- ►endojournals.org J Buchanan, PK Mazumder, P Hu, G … - Endocrinology, 2005 - Endocrine Soc Hyperglycemia is associated with altered myocardial substrate use, a condition
that has been hypothesized to contribute to impaired cardiac performance. The
goals of this study were to determine whether changes in cardiac ... Cited by 69 - Related articles - BL Direct - All 5 versions
D An, B Rodrigues - American Journal of Physiology- Heart and Circulatory …, 2006 - Am Physiological Soc In patients with diabetes, an increased risk of symptomatic heart failure
usually develops in the presence of hypertension or ischemic heart disease.
However, a predisposition to heart failure might also reflect the effects ... Cited by 67 - Related articles - BL Direct - All 5 versions
- ►physiology.org AN Carley, LM Semeniuk, Y Shimoni, E Aasum … - American Journal of Physiology- Endocrinology And …, 2004 - Am Physiological Soc Hearts from insulin-resistant type 2 diabetic db/db mice exhibit features of a
diabetic cardiomyopathy with altered metabolism of exogenous substrates and
reduced contractile performance. Therefore, the effect of chronic oral ... Cited by 59 - Related articles - BL Direct - All 5 versions
OJ How, E Aasum, DL Severson, WY Chan, … - Diabetes, 2006 - Am Diabetes Assoc Altered cardiac metabolism and function (diabetic cardiomyopathy) has been
observed in diabetes. We hypothesize that cardiac efficiency, the ratio of
cardiac work (pressure-volume area [PVA]) and myocardial oxygen consumption ... Cited by 58 - Related articles - BL Direct - All 5 versions
AJ Murray, M Panagia, D Hauton, GF Gibbons, … - Diabetes, 2005 - Am Diabetes Assoc Diabetic patients have abnormal cardiac energy metabolism associated with high
plasma free fatty acid (FFA) concentrations. We investigated whether high plasma
FFAs increase mitochondrial uncoupling protein (UCP) levels in the mouse ... Cited by 53 - Related articles - BL Direct - All 5 versions