- ►harvard.edu [PDF] M Stumvoll, BJ Goldstein, TW van Haeften - The Lancet, 2005 - Elsevier Type 2 diabetes mellitus has become an epidemic, and virtually no physician is
without patients who have the disease. Whereas insulin insensitivity is an early
phenomenon partly related to obesity, pancreas β-cell function declines ... Cited by 433 - Related articles - All 17 versions
- Free from Publisher B Ahrén, R Gomis, E Standl, D Mills, A … - Diabetes Care, 2004 - Am Diabetes Assoc RESULTS—In patients randomized to LAF237, baseline HbA 1c averaged 7.7 ± 0.1%
and decreased at week 12 (Δ = −0.6 ± 0.1%), whereas HbA 1c did not change
from a baseline of 7.9 ± 0.1% in patients given placebo (between-group ... Cited by 310 - Related articles - BL Direct - All 8 versions
R Weiss, S Dufour, SE Taksali, WV Tamborlane … - The Lancet, 2003 - Elsevier Peripheral glucose disposal was significantly lower in individuals with impaired
than in those with normal glucose tolerance (mean 35·4 [SE 4·0] vs 60·6
[7·2] moles per kg lean body mass per min; p=0·023) owing to a reduction ... Cited by 190 - Related articles - All 6 versions
E Bonora, S Kiechl, J Willeit, F … - Diabetes, 2004 - Am Diabetes Assoc Incidence rates and risk factors for type 2 diabetes in low-risk populations are
not well documented. We investigated these in white individuals who were aged
40–79 years and from the population of Bruneck, Italy. Of an age- and sex- ... Cited by 96 - Related articles - BL Direct - All 4 versions
G Pacini, A Mari - Best Practice & Research Clinical Endocrinology & …, 2003 - Elsevier The quantitative assessment of insulin sensitivity (IS) and β-cell function
(BCF) is fundamental in the study of metabolic disorders. The most relevant
experimental tests and data analysis methods for assessing both IS and BCF ... Cited by 84 - Related articles - All 6 versions
- ►physiology.org A Caumo, L Luzi - American Journal of Physiology- Endocrinology And …, 2004 - Am Physiological Soc To fulfill its preeminent function of regulating glucose metabolism, insulin
secretion must not only be quantitatively appropriate but also have qualitative,
dynamic properties that optimize insulin action on target tissues. This ... Cited by 41 - Related articles - All 3 versions
M Fukushima, M Usami, M Ikeda, Y Nakai, A … - Metabolism, 2004 - Elsevier To evaluate the factors causing glucose intolerance in type 2 diabetes in Japan,
insulin secretion and insulin sensitivity were compared across the range of
glucose tolerance. Subjects were divided into 3 groups: normal glucose ... Cited by 43 - Related articles - All 8 versions
- Free from Publisher C Thamer, M Stumvoll, A Niess, O Tschritter, … - Diabetes Care, 2003 - Am Diabetes Assoc RESEARCH DESIGN AND METHODS—In the present study, we specifically tested the
hypothesis that a family history of T2DM is associated with reduced Vo 2max ,
measured by incremental bicycle ergometry, independent of insulin ... Cited by 37 - Related articles - BL Direct - All 5 versions
- ►diabetesjournals.org SA Arslanian, F Bacha, R Saad, N Gungor - Diabetes Care, 2005 - Am Diabetes Assoc RESEARCH DESIGN AND METHODS—A total of 28 healthy white children (12 boys and
16 girls; 12.1 ± 0.5 years of age) with a positive family history of type 2
diabetes and 26 healthy white children (13 boys and 13 girls; 11.5 ± 0.4 ... Cited by 36 - Related articles - All 6 versions
- ►diabetesjournals.org R Weiss, S Caprio, M Trombetta, SE Taksali … - Diabetes, 2005 - Am Diabetes Assoc The profile of insulin secretion and the role of proinsulin processing across
the spectrum of glucose tolerance in obese youth have not been studied. The aims
of this study were to define the role of insulin secretion and proinsulin ... Cited by 28 - Related articles - All 4 versions
