RS Jope, GVW Johnson - Trends in biochemical sciences, 2004 - Elsevier Glycogen synthase kinase-3 (GSK3) is now recognized as a key component of a
surprisingly large number of cellular processes and diseases. Several mechanisms
play a part in controlling the actions of GSK3, including phosphorylation, ... Cited by 485 - Related articles - All 5 versions
- ►sb-roscoff.fr [PDF] L Meijer, M Flajolet, P Greengard - Trends in pharmacological sciences, 2004 - Elsevier Three closely related forms of glycogen synthase kinase 3 (GSK-3α, GSK-3β and
GSK-3β2) have a major role in Wnt and Hedgehog signaling pathways and regulate
the cell-division cycle, stem-cell renewal and differentiation, apoptosis, ... Cited by 185 - Related articles - All 12 versions
JJ Trowbridge, A Xenocostas, RT Moon, M … - Nature medicine, 2006 - fhs.mcmaster.ca The in vivo regulation of hematopoietic stem cell (HSC) function is poorly
understood. Here, we show that hematopoietic repopulation can be augmented by
administration of a glycogen synthase kinase-3 (GSK-3) inhibitor to ... Cited by 91 - Related articles - BL Direct - All 7 versions
AS Wagman, KW Johnson, DE Bussiere - Current pharmaceutical design, 2004 - ingentaconnect.com Abstract: Originally identified as a modulator of glycogen metabolism, glycogen
synthase kinase-3 (GSK3) is now understood to play an important regulatory role
in a variety of pathways including initiation of protein synthesis, cell ... Cited by 76 - Related articles - BL Direct - All 5 versions
JI Yook, XY Li, I Ota, ER Fearon, SJ Weiss - Journal of Biological Chemistry, 2005 - ASBMB Down-regulation of E-cadherin marks the initiation of the epithelial-mesenchymal
transition, a process exploited by invasive cancer cells. The zinc finger
transcription factor, Snail, functions as a potent repressor of E-cadherin ... Cited by 70 - Related articles - All 5 versions
JT Murray, DG Campbell, N Morrice, GC Auld, … - Biochemical Journal, 2004 - pubmedcentral.nih.gov James T. MURRAY*1, David G. CAMPBELL*, Nicholas MORRICE*, Gillian C. AULD*,
Natalia SHPIRO†, Rodolpho MARQUEZ†, Mark PEGGIE*, Jenny BAIN‡, Graham B.
BLOOMBERG§, Florian GRAHAMMER, Florian LANG, Peer WULFF¶, Dietmar KUHL** ... Cited by 68 - Related articles - All 8 versions
- ►nih.gov RS Jope, CJ Yuskaitis, E Beurel - Neurochemical research, 2007 - Springer Abstract Deciphering what governs inflammation and its effects on tissues is
vital for understanding many pathologies. The recent discovery that glycogen
synthase kinase-3 (GSK3) promotes inflammation reveals a new component of ... Cited by 70 - Related articles - BL Direct - All 5 versions
- ►endojournals.org C Bouche, S Serdy, CR Kahn, AB Goldfine - Endocrine reviews, 2004 - Endocrine Soc Type 2 diabetes is a complex disorder with diminished insulin secretion and
insulin action contributing to the hyperglycemia and wide range of metabolic
defects that underlie the disease. The contribution of glucose metabolic ... Cited by 51 - Related articles - BL Direct - All 6 versions
K MacAulay, E Hajduch, AS Blair, MP … - European Journal of Biochemistry, 2003 - interscience.wiley.com Glycogen synthase kinase 3 (GSK3) is inactivated by insulin and lithium and,
like insulin, Li also activates glycogen synthase (GS) via inhibition of GSK3.
Li also mimics insulin's ability to stimulate glucose transport (GT), an ... Cited by 48 - Related articles - BL Direct - All 6 versions
