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Scholar Results 1 - 10 of about 32 citing Delibegovic: Disruption of the striated muscle glycogen targeting subunit PPP1R3A of protein.... (0.10 sec) 

[PDF] The human obesity gene map: the 2005 update


T Rankinen, A Zuberi, YC Chagnon, SJ Weisnagel, G … - Obesity, 2006 - pbrc.edu
Abstract RANKINEN, TUOMO, AAMIR ZUBERI, YVON C. CHAGNON, S. JOHN
WEISNAGEL, GEORGE ARGYROPOULOS, BRANDON WALTS, LOUIS PE´RUSSE, AND CLAUDE
BOUCHARD. The human obesity gene map: the 2005 update. Obesity. 2006;14: ...
Cited by 335 - Related articles - View as HTML - All 6 versions

[PDF] The human obesity gene map: the 2004 update


L Perusse, T Rankinen, A Zuberi, YC Chagnon, … - Obesity …, 2005 - informatik.hu-berlin.de
Abstract PE´ RUSSE, LOUIS, TUOMO RANKINEN, AAMIR ZUBERI, YVON C. CHAGNON, S.
JOHN WEISNAGEL, GEORGE ARGYROPOULOS, BRANDON WALTS, ERIC E. SNYDER, AND
CLAUDE BOUCHARD. The human obesity gene map: the 2004 update. Obes Res. 2005; ...
Cited by 210 - Related articles - View as HTML - All 6 versions

Functional diversity of protein phosphatase-1, a cellular economizer and reset …

- physiology.org
H Ceulemans, M Bollen - Physiological reviews, 2004 - Am Physiological Soc
About one-third of all eukaryotic proteins are controlled by phosphorylation of specific
serine, threonine, and/or tyrosine residues. Most phosphorylations are reversible, implying that
the phosphorylation level of a protein reflects the balance between the activities of the ...
Cited by 209 - Related articles - BL Direct - All 7 versions

Role that phosphorylation of GSK3 plays in insulin and Wnt signalling defined by …


EJ McManus, K Sakamoto, LJ Armit, L … - The EMBO …, 2005 - pubmedcentral.nih.gov
The inactivation of glycogen synthase kinase (GSK)3 has been proposed to play important roles
in insulin and Wnt signalling. To define the role that inactivation of GSK3 plays, we generated
homozygous knockin mice in which the protein kinase B phosphorylation sites on GSK3α ( ...
Cited by 142 - Related articles - All 6 versions

The α2–5′ AMP-activated protein kinase is a site 2 glycogen synthase kinase in …


SB Jørgensen, JN Nielsen, JB Birk, GS Olsen, B Viollet, … - Diabetes, 2004 - Am Diabetes Assoc
The 5'AMP-activated protein kinase (AMPK) is a potential antidiabetic drug target. Here we show
that the pharmacological activation of AMPK by 5-aminoimidazole-1-ß-4-carboxamide ribofuranoside
(AICAR) leads to inactivation of glycogen synthase (GS) and phosphorylation of GS at Ser ...
Cited by 63 - Related articles - BL Direct - All 4 versions

The cellular fate of glucose and its relevance in type 2 diabetes

- endojournals.org
C Bouche, S Serdy, CR Kahn, AB Goldfine - Endocrine reviews, 2004 - Endocrine Soc
Type 2 diabetes is a complex disorder with diminished insulin secretion and insulin action contributing
to the hyperglycemia and wide range of metabolic defects that underlie the disease. The contribution
of glucose metabolic pathways per se in the pathogenesis of the disease remains ...
Cited by 53 - Related articles - BL Direct - All 6 versions

Protein phosphatase inhibition: structure based design. Towards new therapeutic …


JA Sakoff, A McCluskey - Current pharmaceutical design, 2004 - ingentaconnect.com
Abstract: Cellular signalling processes are governed by a delicate balance of phosphatase and
kinase activity. Over the past few years there has been considerable effort directed toward the
development of kinase based therapeutic agents, whilst phosphatase based therapeutics ...
Cited by 29 - Related articles - BL Direct - All 3 versions

Role of the PDK1–PKB–GSK3 pathway in regulating glycogen synthase and …


A Mora, K Sakamoto, EJ McManus, DR Alessi - FEBS letters, 2005 - Elsevier
In order to investigate the importance of the PDK1–PKB–GSK3 signalling network in regulating
glycogen synthase (GS) in the heart, we have employed tissue specific conditional knockout
mice lacking PDK1 in muscle (mPDK1 −/− ), as well as knockin mice in which the protein ...
Cited by 28 - Related articles - All 7 versions

Muscle-specific deletion of the Glut4 glucose transporter alters multiple regulatory …

- nih.gov
YB Kim, OD Peroni, WG Aschenbach, Y … - Science's …, 2005 - stke.sciencemag.org
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Cited by 23 - Related articles - BL Direct - All 9 versions

Protein targeting to glycogen overexpression results in the specific enhancement of …


CC Greenberg, KN Meredith, L Yan, MJ Brady - Journal of Biological Chemistry, 2003 - ASBMB
Protein phosphatase-1 (PP1) plays an important role in the regulation of glycogen synthesis
by insulin. Protein targeting to glycogen (PTG) enhances glycogen accumulation by increasing
PP1 activity against glycogen-metabolizing enzymes. However, the specificity of PTG's ...
Cited by 21 - Related articles - BL Direct - All 3 versions


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