W van Dijk… - Current opinion in lipidology, 2004 - journals.lww.com Recent findings: It has now been firmly established that variation in plasma triglyceride levels
in a wide range of human populations is strongly associated with genetic variation at the chromosomal
locus encoding both the APOC3 and APOA5 genes, the APOA1/C3/A4/A5 gene cluster. ... Cited by 82 - Related articles - BL Direct - All 7 versions
D An, B Rodrigues - American Journal of Physiology- Heart and …, 2006 - Am Physiological Soc In patients with diabetes, an increased risk of symptomatic heart failure usually develops in the
presence of hypertension or ischemic heart disease. However, a predisposition to heart failure
might also reflect the effects of underlying abnormalities in diastolic function that can ... Cited by 67 - Related articles - BL Direct - All 5 versions
- ►endojournals.org PJ Voshol, G Haemmerle, DM Ouwens, R Zimmermann … - Endocrinology, 2003 - Endocrine Soc Hormone-sensitive lipase (HSL) is a major enzyme for triglyceride (TG) lipolysis in adipose
tissue. In HSL-knockout mice, plasma free fatty acid and TG levels are low, associated with low
liver TG content. Because a decreased hepatic insulin sensitivity has been reported to be ... Cited by 53 - Related articles - BL Direct - All 5 versions
- ►diabetesjournals.org JM Miles, YS Park, D Walewicz, C Russell-Lopez, S … - Diabetes, 2004 - Am Diabetes Assoc Little is known about the fate of the lipolytic products produced by the action of lipoprotein lipase
(LPL) on circulating triglyceride-rich lipoproteins in humans. We studied eight lean, healthy male
subjects after an overnight fast. Subjects received infusions of lipid emulsions containing ... Cited by 47 - Related articles - BL Direct - All 5 versions
- ►umich.edu [PDF] JF Horowitz - Trends in Endocrinology & Metabolism, 2003 - Elsevier By far the largest energy reserve in the human body is adipose tissue triglycerides, and these
reserves are an important source of fuel during prolonged endurance exercise. To use this rich
source of potential energy during exercise, adipose tissue triglycerides must first be ... Cited by 40 - Related articles - All 10 versions
- ►physiology.org D An, T Pulinilkunnil, D Qi, S Ghosh, A … - American Journal of …, 2005 - Am Physiological Soc The "fuel gauge" AMP-activated protein kinase (AMPK) facilitates ATP production to meet energy
demands during metabolic stress. Given the importance of lipoprotein lipase (LPL) in providing
hearts with fatty acids (FA), the preferred substrate consumed by the heart, the objective ... Cited by 38 - Related articles - All 4 versions
- ►endojournals.org BR Barrows, EJ Parks - Journal of Clinical Endocrinology & Metabolism, 2006 - Endocrine Soc Design/Intervention: Subjects were duodenally fed a formula labeled with the stable isotope
glyceryl tri-palmitate-d 31 and iv infused with [1,2,3,4- 13 C 4 ]-palmitatic acid and [1- 13 C 1
]-acetate to quantitate the liver's use of FAs originating from adipose tissue and de novo ... Cited by 35 - Related articles - BL Direct - All 4 versions
- ►aspetjournals.org RK Vikramadithyan, K Hirata, H Yagyu, Y Hu, A … - Journal of Pharmacology …, 2005 - ASPET The three known members of the ligand-activated peroxisome proliferator-activated receptor
(PPAR) family of nuclear receptors are , / , and (Schoonjans et al., 1997 Go ; Braissant and
Wahli, 1998 Go ). PPAR is highly expressed in liver, heart, and skeletal muscle; PPAR is ... Cited by 35 - Related articles - All 5 versions
- ►jlr.org JR Goudriaan, S Santo, E MS, PJ Voshol, B … - The Journal of Lipid …, 2004 - ASBMB The VLDL receptor (VLDLr) is a member of the LDL receptor (LDLr) family (1). The most striking
features that distinguish the VLDLr from the LDLr are its ligand-binding properties and its tissue
distribution (1, 2). The VLDLr is, like lipoprotein lipase (LPL), uniquely expressed at sites ... Cited by 34 - Related articles - BL Direct - All 5 versions
- ►jlr.org AC Heijboer, E Donga, PJ Voshol, ZC Dang, LM … - The Journal of Lipid …, 2005 - ASBMB Fasting readily induces hepatic steatosis. Hepatic steatosis is associated with hepatic insulin
resistance. The purpose of the present study was to document the effects of 16 h of fasting in
wild-type mice on insulin sensitivity in liver and skeletal muscle in relation to 1) tissue ... Cited by 29 - Related articles - All 4 versions
