H Yki-Jarvinen - New England Journal of Medicine, 2004 - content.nejm.org Insulin resistance both precedes and predicts type 2 diabetes mellitus. 1
Although exercise and weight loss ameliorate insulin resistance and may in some
cases prevent or delay onset of the disease, 2 therapy that combats insulin ... Cited by 838 - Related articles - BL Direct - All 6 versions
PA Kern, GB Di Gregorio, T Lu, N Rassouli, … - Diabetes, 2003 - Am Diabetes Assoc Adiponectin is a 29-kDa adipocyte protein that has been linked to the insulin
resistance of obesity and lipodystrophy. To better understand the regulation of
adiponectin expression, we measured plasma adiponectin and adipose tissue ... Cited by 371 - Related articles - BL Direct - All 6 versions
- ►cdlib.org [PDF] PJ Havel - Diabetes, 2004 - Am Diabetes Assoc Hormones produced by adipose tissue play a critical role in the regulation of
energy intake, energy expenditure, and lipid and carbohydrate metabolism. This
review will address the biology, actions, and regulation of three adipocyte ... Cited by 339 - Related articles - BL Direct - All 7 versions
M Tiikkainen, AM Häkkinen, E Korsheninnikova … - Diabetes, 2004 - Am Diabetes Assoc Both rosiglitazone and metformin increase hepatic insulin sensitivity, but their
mechanism of action has not been compared in humans. The objective of this study
was to compare the effects of rosiglitazone and metformin treatment on ... Cited by 276 - Related articles - BL Direct - All 6 versions
A Lihn, SB Pedersen, B Richelsen - Obes Rev, 2005 - edulife.com.br Blackwell Science, LtdOxford, UKOBRobesity reviews1467-78812004 The
International Association for the Study of Obesity611321Review
ArticleAdiponectin, regulation and association to insulin sen- sitivity AS ... Cited by 152 - Related articles - View as HTML - All 8 versions
- ►endojournals.org AM Xydakis, CC Case, PH Jones, RC … - Journal of Clinical Endocrinology & Metabolism, 2004 - Endocrine Soc Severe obesity increases the prevalence of the metabolic syndrome, and moderate
acute weight loss with a very low-calorie diet in obese subjects with the
metabolic syndrome leads to significant metabolic benefits. Adiponectin has ... Cited by 144 - Related articles - BL Direct - All 5 versions
JP Whitehead, AA Richards, IJ Hickman, GA … - Diabetes Obesity and Metabolism, 2006 - pt.wkhealth.com Adiponectin is a recently described adipokine that has been recognized as a key
regulator of insulin sensitivity and tissue inflammation. It is produced by
adipose tissue (white and brown) and circulates in the blood at very high ... Cited by 130 - Related articles - BL Direct - All 6 versions
- ►endojournals.org KM Utzschneider, SE Kahn - Journal of Clinical Endocrinology & Metabolism, 2006 - Endocrine Soc Evidence Synthesis: Insulin resistance in NAFLD is characterized by reductions
in whole-body, hepatic, and adipose tissue insulin sensitivity. The mechanisms
underlying the accumulation of fat in the liver may include excess dietary ... Cited by 115 - Related articles - BL Direct - All 4 versions
- ►diabetesjournals.org B Brunmair, K Staniek, F Gras, N Scharf, A … - Diabetes, 2004 - Am Diabetes Assoc Metformin and thiazolidinediones (TZDs) are believed to exert their antidiabetic
effects via different mechanisms. As evidence suggests that both impair cell
respiration in vitro, this study compared their effects on mitochondrial ... Cited by 110 - Related articles - BL Direct - All 5 versions
- ►endojournals.org Y Miyazaki, A Mahankali, E Wajcberg, M … - Journal of Clinical Endocrinology & Metabolism, 2004 - Endocrine Soc We examined the effect of pioglitazone (PIO) on circulating adipocytokine levels
to elucidate the mechanisms by which thiazolidinediones improve insulin
resistance in type 2 diabetes mellitus (T2DM). Twenty-three subjects with ... Cited by 115 - Related articles - BL Direct - All 5 versions