- ►nih.gov SE Shoelson, J Lee, AB Goldfine - Journal of Clinical Investigation, 2006 - Am Soc Clin Investig Over a hundred years ago, high doses of salicylates were shown to lower glucose levels in diabetic
patients. This should have been an important clue to link inflammation to the pathogenesis of
type 2 diabetes (T2D), but the antihyperglycemic and antiinflammatory effects of ... Cited by 421 - Related articles - BL Direct - All 11 versions
JC Pickup - Diabetes care, 2004 - Am Diabetes Assoc There is increasing evidence that an ongoing cytokine-induced acute-phase response (sometimes
called low-grade inflammation, but part of a widespread activation of the innate immune
system) is closely involved in the pathogenesis of type 2 diabetes and associated ... Cited by 365 - Related articles - BL Direct - All 8 versions
- ►diabetesjournals.org FB Hu, JB Meigs, TY Li, N Rifai, JAE Manson - Diabetes, 2004 - Am Diabetes Assoc We conducted a prospective, nested, case-control study of inflammatory markers as predictors
of type 2 diabetes among 32,826 women who provided blood samples in 1989 through 1990
in the Nurses' Health Study. Among women free of diabetes, cardiovascular disease, or ... Cited by 235 - Related articles - BL Direct - All 7 versions
EL Ding, Y Song, VS Malik, S Liu - Jama, 2006 - Am Med Assoc You are seeing this message because your Web browser does not support basic Web
standards. Find out more about why this message is appearing and what you can do to make
your experience on this site better. ... Context Inconsistent data suggest that endogenous ... Cited by 171 - Related articles - BL Direct - All 7 versions
S Kaser, A Kaser, A Sandhofer, CF Ebenbichler, H … - … and Biophysical Research …, 2003 - Elsevier Resistin is a recently discovered polypeptide that induces insulin resistance in rodents. While
in rodents resistin is predominantly expressed in adipocytes, in humans peripheral blood mononuclear
cells (PBMC) seem to a be a major source of resistin. In the present study, we show that in ... Cited by 164 - Related articles - All 5 versions
MY Donath, J Størling, K Maedler, T Mandrup- … - Journal of Molecular …, 2003 - Springer Abstract Pancreatic islet β-cell death occurs in type 1 and 2 diabetes mellitus, leading to absolute
or relative insulin deficiency. β-cell death in type 1 diabetes is due predominantly to
autoimmunity. In type 2 diabetes β-cell death occurs as the combined consequence of ... Cited by 145 - Related articles - BL Direct - All 3 versions
SE Shoelson, L Herrero, A Naaz - Gastroenterology, 2007 - Elsevier Weight gain and obesity are major risk factors for conditions and diseases ranging from insulin
resistance and type 2 diabetes mellitus to atherosclerosis and the sequelae of nonalcoholic fatty
liver disease. A chronic, subacute state of inflammation often accompanies the ... Cited by 149 - Related articles - All 23 versions
- ►case.edu [PDF] L Pirola, AM Johnston, EV Obberghen - Diabetologia, 2004 - Springer Insulin is a key hormone regulating the control of metabolism and the maintenance of normoglycaemia
and normolipidaemia. Insulin acts by binding to its cell surface receptor, thus activating the receptor's
intrinsic tyrosine kinase activity, resulting in receptor autophos- phorylation and ... Cited by 136 - Related articles - BL Direct - All 6 versions
- ►angrylapdog.com T Bobbert, H Rochlitz, U Wegewitz, S … - …, 2005 - diabetes.diabetesjournals.org.p. … Adiponectin affects lipid metabolism and insulin sensitivity. However, adiponectin circulates in
three different oligomers that may also have distinct biological functions. We aimed to analyze
the role of these oligomers in obesity and lipid metabolism after weight reduction. A total ... Cited by 140 - Related articles - BL Direct - All 8 versions
