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Scholar Results 1 - 10 of about 53 citing Yokota: Role of protein kinase C on the expression of platelet-derived growth factor and.... (0.09 sec) 

Diabetic vascular complications: pathophysiology, biochemical basis and potential …


S Yamagishi, T Imaizumi - Current pharmaceutical design, 2005 - ingentaconnect.com
Abstract: Diabetic vascular complication is a leading cause of end-stage renal
failure, acquired blindness, a variety of neuropathies and accelerated
atherosclerosis, which could account for disabilities and high mortality ...
Cited by 123 - Related articles - All 3 versions

Inhibition of platelet-derived growth factor promotes pericyte loss and angiogenesis in …

- amjpathol.org
JL Wilkinson-Berka, S Babic, T de Gooyer, AW … - American Journal of Pathology, 2004 - ASIP
We investigated whether inhibition of platelet-derived growth factor (PDGF)
receptor tyrosine kinase activity would affect pericyte viability, vascular
endothelial growth factor (VEGF)/vascular endothelial growth factor ...
Cited by 47 - Related articles - BL Direct - All 5 versions

Reduction of Diabetes-Induced Oxidative Stress, Fibrotic Cytokine Expression, and Renal …

- shouxi.net
Y Ohshiro, RC Ma, Y Yasuda, J Hiraoka- … - Diabetes, 2006 - Am Diabetes Assoc
Diabetes induces the activation of several protein kinase C (PKC) isoforms in
the renal glomeruli. We used PKC-β −/− mice to examine the action of PKC-β
isoforms in diabetes-induced oxidative stress and renal injury at 8 and 24 ...
Cited by 38 - Related articles - BL Direct - All 6 versions

The roles of lipids and protein kinase Cs in the pathogenesis of diabetic retinopathy


TM Curtis, CN Scholfield - Diabetes/Metabolism Reviews - interscience.wiley.com
Diabetic retinopathy is one of the most common complications of diabetes and is
a major cause of new blindness in the working-age population of developed
countries. While the exact pathogenic basis of this condition remains ill ...
Cited by 38 - Related articles - BL Direct - All 3 versions

Microvascular complications of diabetes


Z He, GL King - Endocrinology and metabolism clinics of North America, 2004 - Elsevier
Microvascular complications in diabetes contribute to pathologic and functional
changes in many tissues, including eye, heart, kidney, skin, and neuronal
tissues. Based on the tissues affected, these changes are traditionally ...
Cited by 35 - Related articles - BL Direct - All 4 versions

Angiogenic and antiangiogenic factors in proliferative diabetic retinopathy


R Simo, E Carrasco, M Garcia-Ramirez, C … - Current Diabetes Reviews, 2006 - ingentaconnect.com
Abstract: Diabetic retinopathy continues to be the leading cause of legal
blindness among working-age individuals. The earliest histological features of
diabetic retinopathy include neuroretinal damage, capillary basement ...
Cited by 36 - Related articles - BL Direct - All 2 versions

Ruboxistaurin, a Protein Kinase C {beta} Inhibitor, as an Emerging Treatment for Diabetes …


SV Joy, AC Scates, S Bearelly, M Dar, CA … - The Annals of pharmacotherapy, 2005 - Harvey Whitney Books
Published Online, 13 September 2005, www.theannals.com, DOI 10.1345/aph.1E572.
The Annals of Pharmacotherapy: Vol. 39, No. 10, pp. 1693-1699. DOI
10.1345/aph.1E572 © 2005 Harvey Whitney Books Company.
Cited by 31 - Related articles - All 4 versions

In high glucose protein kinase C-ζ activation is required for mesangial cell generation of …


J Kwan, H Wang, S Munk, L Xia, HJ Goldberg, … - Kidney international, 2005 - nature.com
We postulated that in mesangial cells exposed to high glucose, protein kinase C-
(PKC- ) is necessary for the generation of reactive oxygen species (ROS) by
nicotinamide adenine dinucleotide phosphate (NADPH) oxidase and that the ...
Cited by 25 - Related articles - BL Direct - All 4 versions

[PDF] Growth factors in proliferative diabetic retinopathy


ZA Khan, S Chakrabarti - Experimental Diabesity Research, 2003 - hindawi.com
Many growth factors are implicated in the pathogenesis of proliferative diabetic
retinopathy. Alteration of growth factors and their receptors in diabetes has
been shown in both experimental and clinical studies. Sustained hyper- ...
Cited by 22 - Related articles - View as HTML - All 10 versions

Regulation of vascular genes by glucose


OI Stenina - Current pharmaceutical design, 2005 - ingentaconnect.com
Abstract: Endothelial dysfunction is an early sign of diabetic vascular disease.
Due to their unique position at the border between blood and vascular tissue,
endothelial cells (EC) are the first vascular cells to sensor humoral ...
Cited by 21 - Related articles - All 4 versions


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