S Yamagishi, T Imaizumi - Current pharmaceutical design, 2005 - ingentaconnect.com Abstract: Diabetic vascular complication is a leading cause of end-stage renal
failure, acquired blindness, a variety of neuropathies and accelerated
atherosclerosis, which could account for disabilities and high mortality ... Cited by 123 - Related articles - All 3 versions
- ►amjpathol.org JL Wilkinson-Berka, S Babic, T de Gooyer, AW … - American Journal of Pathology, 2004 - ASIP We investigated whether inhibition of platelet-derived growth factor (PDGF)
receptor tyrosine kinase activity would affect pericyte viability, vascular
endothelial growth factor (VEGF)/vascular endothelial growth factor ... Cited by 47 - Related articles - BL Direct - All 5 versions
- ►shouxi.net Y Ohshiro, RC Ma, Y Yasuda, J Hiraoka- … - Diabetes, 2006 - Am Diabetes Assoc Diabetes induces the activation of several protein kinase C (PKC) isoforms in
the renal glomeruli. We used PKC-β −/− mice to examine the action of PKC-β
isoforms in diabetes-induced oxidative stress and renal injury at 8 and 24 ... Cited by 38 - Related articles - BL Direct - All 6 versions
TM Curtis, CN Scholfield - Diabetes/Metabolism Reviews - interscience.wiley.com Diabetic retinopathy is one of the most common complications of diabetes and is
a major cause of new blindness in the working-age population of developed
countries. While the exact pathogenic basis of this condition remains ill ... Cited by 38 - Related articles - BL Direct - All 3 versions
Z He, GL King - Endocrinology and metabolism clinics of North America, 2004 - Elsevier Microvascular complications in diabetes contribute to pathologic and functional
changes in many tissues, including eye, heart, kidney, skin, and neuronal
tissues. Based on the tissues affected, these changes are traditionally ... Cited by 35 - Related articles - BL Direct - All 4 versions
R Simo, E Carrasco, M Garcia-Ramirez, C … - Current Diabetes Reviews, 2006 - ingentaconnect.com Abstract: Diabetic retinopathy continues to be the leading cause of legal
blindness among working-age individuals. The earliest histological features of
diabetic retinopathy include neuroretinal damage, capillary basement ... Cited by 36 - Related articles - BL Direct - All 2 versions
J Kwan, H Wang, S Munk, L Xia, HJ Goldberg, … - Kidney international, 2005 - nature.com We postulated that in mesangial cells exposed to high glucose, protein kinase C-
(PKC- ) is necessary for the generation of reactive oxygen species (ROS) by
nicotinamide adenine dinucleotide phosphate (NADPH) oxidase and that the ... Cited by 25 - Related articles - BL Direct - All 4 versions
ZA Khan, S Chakrabarti - Experimental Diabesity Research, 2003 - hindawi.com Many growth factors are implicated in the pathogenesis of proliferative diabetic
retinopathy. Alteration of growth factors and their receptors in diabetes has
been shown in both experimental and clinical studies. Sustained hyper- ... Cited by 22 - Related articles - View as HTML - All 10 versions
OI Stenina - Current pharmaceutical design, 2005 - ingentaconnect.com Abstract: Endothelial dysfunction is an early sign of diabetic vascular disease.
Due to their unique position at the border between blood and vascular tissue,
endothelial cells (EC) are the first vascular cells to sensor humoral ... Cited by 21 - Related articles - All 4 versions