JL Wilkinson-Berka - Current pharmaceutical design, 2004 - ingentaconnect.com Abstract: The pathogenetic agents involved in the development of diabetic
retinopathy are diverse. In the setting of hyperglycaemia and retinal hypoxia a
number of vasoactive factors may interact to promote pathology in a variety ... Cited by 66 - Related articles - BL Direct - All 5 versions
JWB Bainbridge, MH Tan, RR Ali - Gene therapy, 2006 - nature.com The eye has unique advantages as a target organ for gene therapy of both
inherited and acquired ocular disorders and offers a valuable model system for
gene therapy. The eye is readily accessible to phenotypic examination and ... Cited by 44 - Related articles - BL Direct - All 4 versions
EL Fletcher, JA Phipps, JL Wilkinson-Berka - Clinical & experimental optometry: journal of the …, 2005 - ncbi.nlm.nih.gov Diabetic retinopathy is the leading cause of blindness in those of working age.
It is well known that the retinal vasculature is altered during diabetes. More
recently, it has emerged that neuronal and glial dysfunction occurs in ... Cited by 23 - Related articles - All 4 versions
C Lebherz, AM Maguire, A Auricchio, W Tang, … - Diabetes, 2005 - Am Diabetes Assoc Neovascularization leads to blindness in numerous ocular diseases, including
diabetic retinopathy, age-related macular degeneration, retinopathy of
prematurity, and sickle cell disease. More effective and stable treatments ... Cited by 20 - Related articles - All 8 versions
- ►iovs.org J Aranda, JC Rivera, MC Jeziorski, J Riesgo- … - Investigative ophthalmology & visual science, 2005 - ARVO PURPOSE. Disruption of the normally antiangiogenic environment of the retina
leads to aberrant angiogenesis, the major cause of vision loss throughout the
world. Prolactin (PRL), the hormone originally associated with milk ... Cited by 21 - Related articles - BL Direct - All 3 versions
CM Lai, SA Dunlop, LA May, M Gorbatov, M … - British Journal of Ophthalmology, 2005 - bjo.bmj.com Results: One transgenic line expressing low hVEGF levels showed mild clinical
changes such as focal fluorescein leakage, microaneurysms, venous tortuosity,
capillary non-perfusion and minor neovascularisation, which remained stable ... Cited by 18 - Related articles - All 9 versions
PK Buch, JW Bainbridge, RR Ali - Gene Therapy, 2008 - nature.com A wide range of retinal disorders can potentially be treated using viral
vector-mediated gene therapy. The most widely used vectors for ocular gene
delivery are based on adeno-associated virus (AAV), because they elicit ... Cited by 15 - Related articles - BL Direct - All 3 versions
WY Shen, CM Lai, CE Graham, N Binz, YKY Lai … - Diabetologia, 2006 - Springer Page 1. Diabetologia (2006) 49: 1690–1701 DOI 10.1007/s00125-006-0274-8 ARTICLE
W.-Y. Shen . CM Lai . CE Graham . N. Binz . YKY Lai . J. Eade . D. Guidolin . ... Cited by 12 - Related articles - BL Direct - All 4 versions
R Ghassemifar, CM Lai, PE Rakoczy - Cell and tissue research, 2006 - Springer Abstract Tight junctions (TJ) between retinal pigmented epithelial (RPE) and
retinal endothelial cells maintain the outer and inner blood-retinal barrier,
and the breakdown of these barriers is associated with retinal diseases. ... Cited by 9 - Related articles - All 2 versions
B Yang, P Lin, KM Carrick, JA McNulty, LG … - Biochemical and biophysical research communications, 2005 - Elsevier We investigated the effect of peroxisome proliferator-activated receptor gamma
(PPARγ) agonists on serum vascular endothelial growth factor (VEGF) in
diet-induced insulin resistant SD rats and ZDF rats. SD rats fed a high fat/ ... Cited by 8 - Related articles - All 5 versions
