- ►nih.gov IG Obrosova, P Pacher, C Szabó, Z … - Diabetes, 2005 - Am Diabetes Assoc This study evaluated the effects of aldose reductase inhibition on
diabetes-induced oxidative-nitrosative stress and poly(ADP-ribose) polymerase
(PARP) activation. In animal experiments, control and ... Cited by 73 - Related articles - All 8 versions
- ►iovs.org J Zhou, AS Menko - Investigative ophthalmology & visual science, 2004 - ARVO METHODS. Embryonic day (E)10 chick lenses were cultured in Medium 199 containing
10% fetal bovine serum. The activation state of Src kinases and the MAP kinases
extracellular signal-regulated protein kinase (ERK), c-jun N-terminal ... Cited by 13 - Related articles - BL Direct - All 3 versions
- ►iovs.org G Chandrasekher, D Sailaja - Investigative ophthalmology & visual science, 2004 - ARVO METHODS. Apoptosis in rabbit lens epithelial cell cultures was induced by
staurosporine (10 ng/mL). Cellular apoptosis was detected by identifying the
characteristic ladder-like fragmentation of genomic DNA in agarose gels and ... Cited by 11 - Related articles - BL Direct - All 4 versions
ER James - Journal of Ocular Pharmacology and Therapeutics, 2007 - liebertonline.com Steroid-induced posterior subcapsular cataracts (PSCs) exhibit three main
distinctive char- acteristics: (i) association only with steroids possessing
glucocorticoid activity, (ii) involve- ment of aberrant migrating lens ... Cited by 7 - Related articles - BL Direct - All 4 versions
G Chandrasekher, D Sailaja - Current Eye Research, 2004 - informahealthcare.com Results. Protein tyrosine phosphorylation in the lens was disrupted before the
onset of cataract. A decrease in tyrosine phosphorylation of lens proteins was
observed within 2–3 days of selenite injection (pre-cataract stage). The ... Cited by 6 - Related articles - BL Direct - All 7 versions
H Colitz, C Maria, JA Bomser, DF Kusewitt - International ophthalmology clinics, 2005 - journals.lww.com Ultraviolet (UV) irradiation can damage the lens and over the lifetime of the
individual contributes to the development of age-related cataract. Cataracts
occur in all species, becoming evident by the average age of 65 years in ... Cited by 4 - Related articles - All 3 versions
D Lin, R Harris, R Stutzman, GA Zampighi, H … - Current Eye Research, 2007 - informahealthcare.com Purpose: The purpose of this study is to demonstrate the early activation of the
protein kinase C-γ (PKC-γ) pathway in the streptozotocin (STZ)-induced
diabetic rat lens. Methods: Twelve-week-old male and female Sprague-Dawley ... Cited by 3 - Related articles - BL Direct - All 5 versions
IG Obrosova - BBA-Molecular Basis of Disease, 2009 - Elsevier Diabetes-induced damage to peripheral nerve culminates in development of
peripheral diabetic neuropathy (PDN), one of the most devastating complications
of diabetes mellitus and a leading cause of foot amputation. The ... Cited by 1 - Related articles - All 2 versions