- ►diabetesjournals.org G Wolf, S Chen, FN Ziyadeh - Diabetes, 2005 - Am Diabetes Assoc Nephropathy is a major complication of diabetes. Alterations of mesangial cells
have traditionally been the focus of research in deciphering molecular
mechanisms of diabetic nephropathy. Injury of podocytes, if recognized at ... Cited by 188 - Related articles - All 9 versions
- ►asnjournals.org BL Wharram, M Goyal, JE Wiggins, SK Sanden … - Journal of the American Society of Nephrology, 2005 - Am Soc Nephrol Glomerular injury and proteinuria in diabetes (types 1 and 2) and IgA
nephropathy is related to the degree of podocyte depletion in humans. For
determining the causal relationship between podocyte depletion and ... Cited by 86 - Related articles - BL Direct - All 5 versions
- ►oxfordjournals.org KE White, RW Bilous - Nephrology Dialysis Transplantation, 2004 - ERA-EDTA Results. Podocyte number per glomerulus was significantly lower in the type 2
patients compared with controls [mean (95% confidence interval) 464 (382–546)
vs 589 (543–635), P = 0.004]. Mean glomerular volume was significantly ... Cited by 72 - Related articles - BL Direct - All 5 versions
R Mishra, SN Emancipator, T Kern, MS … - Kidney international, 2005 - nature.com Biochemical (caspase activity, cytochrome-c release, etc.) and morphologic
(chromatin condensation and nuclear segmentation) features of apoptotic cell
death were assessed in cultured human mesangial cells exposed to high ... Cited by 48 - Related articles - All 3 versions
- ►asnjournals.org JE Wiggins, M Goyal, SK Sanden, BL … - Journal of the American Society of Nephrology, 2005 - Am Soc Nephrol Whether podocyte depletion could cause the glomerulosclerosis of aging in
Fischer 344 rats at ages 2, 6, 17, and 24 mo was evaluated. Ad libitum–fed
rats developed proteinuria and glomerulosclerosis by 24 mo, whereas calorie- ... Cited by 50 - Related articles - BL Direct - All 6 versions
- ►asnjournals.org SH Sung, FN Ziyadeh, A Wang, PE Pyagay, … - Journal of the American Society of Nephrology, 2006 - Am Soc Nephrol For investigation of how the vascular endothelial growth factor (VEGF) system
participates in the pathogenesis of diabetic kidney disease, type 2 diabetic
db/db and control db/m mice were treated intraperitoneally with vehicle or ... Cited by 44 - Related articles - BL Direct - All 5 versions
- ►amjpathol.org D Macconi, M Bonomelli, A Benigni, T Plati, F … - American Journal of Pathology, 2006 - ASIP Changes in podocyte number or density have been suggested to play an important
role in renal disease progression. Here, we investigated the temporal
relationship between glomerular podocyte number and development of ... Cited by 44 - Related articles - BL Direct - All 7 versions
B Isermann, IA Vinnikov, T Madhusudhan, S … - Nature medicine, 2007 - basicmed.med.ncku.edu.tw Data providing direct evidence for a causative link between endothelial
dysfunction, microvascular disease and diabetic end-organ damage are scarce.
Here we show that activated protein C (APC) formation, which is regulated ... Cited by 48 - Related articles - View as HTML - BL Direct - All 5 versions
RC Wiggins - Kidney International, 2007 - nature.com Glomerular diseases encompass a broad array of clinicopathologically defined
syndromes which together account for 90% of end-stage kidney disease costing $20
billion per annum to treat in the United States alone. Recent insights have ... Cited by 38 - Related articles - BL Direct - All 3 versions
