- ►shouxi.net S Grinspoon, A Carr - New England Journal of Medicine, 2005 - content.nejm.org From the Program in Nutritional Metabo- lism and the Neuroendocrine Unit, Mas- sachusetts
General Hospital and Harvard Medical School, Boston (SG); and the HIV, Immunology, and Infectious
Diseases Clin- ical Services Unit, St. Vincent's Hospital, Sydney (AC). Address reprint ... Cited by 435 - Related articles - All 7 versions
GA Lee, T Seneviratne, MA Noor, JC Lo, JM Schwarz, … - Aids, 2004 - journals.lww.com From the a Metabolism and Endocrine Sections, San Francisco Department of Veterans Affairs
Medical Center, San Francisco, CA, USA; b Department of Medicine, University of California,
San Francisco, CA, USA; c Division of Endocrinology, San Francisco General Hospital, ... Cited by 130 - Related articles - BL Direct - All 6 versions
D Nolan, E Hammond, I James, E McKinnon, S … - Antiviral Therapy, 2003 - intmedpress.com Objectives: It has been proposed that the contribution of nucleoside-analogue reverse transcriptase
inhibitor (NRTI) therapy to subcutaneous fat wasting involves adipose tissue-specific mitochondrial
DNA toxicity. We have investigated the relationships between NRTI therapy, adipocyte ... Cited by 91 - Related articles - View as HTML - BL Direct - All 4 versions
TT Brown, X Li, SR Cole, LA Kingsley, FJ Palella, SA … - Aids, 2005 - pdfs.journals.lww.com Objective: To estimate insulin resistance and its relationship to antiretroviral therapy (ART) in
a cohort of HIV-infected persons with comparison to HIV-seronegative controls. Design: Prospective
cohort of 533 HIV-infected and 755 HIV-seronegative men in the Multicenter AIDS Cohort ... Cited by 91 - Related articles - BL Direct - All 13 versions
B Gazzard… - HIV medicine, 2005 - pt.wkhealth.com It is important that adherence support should be part of the routine clinical care provided by all
health professionals in HIV medicine rather than being the exclusive role of specialist staff
members. Every prescribing unit should adopt a standardized approach to assessing ... Cited by 37 - Related articles - BL Direct - All 5 versions
J Hertel, H Struthers, CB Horj, PW Hruz - Journal of Biological Chemistry, 2004 - ASBMB Human immunodeficiency virus (HIV) protease inhibitors (PIs) act as reversible noncompetitive
inhibitors of GLUT4 with binding affinities in the low micromolar range and are known to contribute
to alterations in glucose homeostasis during treatment of HIV infection. As aspartyl ... Cited by 42 - Related articles - All 5 versions
A Rudich, R Ben-Romano, S Etzion, N … - Acta Physiologica …, 2005 - interscience.wiley.com Accumulating clinical evidence now links HIV protease inhibitors (HPIs) to the pathogenesis
of insulin resistance, dyslipidaemia, lipodystrophy and atherosclerosis associated with highly
active anti-retroviral therapy. Here we briefly describe the evidence for a distinct causative ... Cited by 34 - Related articles - All 3 versions
- ►aspetjournals.org RA Parker, OP Flint, R Mulvey, C Elosua, F Wang, W … - Molecular pharmacology, 2005 - ASPET The lipid and metabolic disturbances associated with human immunodeficiency virus (HIV) protease
inhibitor therapy in AIDS have stimulated interest in developing new agents that minimize these
side effects in the clinic. The underlying explanation of mechanism remains enigmatic, but ... Cited by 37 - Related articles - All 6 versions
R Ben-Romano, A Rudich, A Tirosh, R Potashnik, T … - Diabetologia, 2004 - Springer Aims/hypothesis. Chronic exposure of 3T3-L1 adipo- cytes to the HIV protease inhibitor nelfinavir
induces insulin resistance, recapitulating key metabolic alter- ations of adipose tissue in the lipodystrophy
syndrome induced by these agents. Our goal was to identify the defect in the insulin ... Cited by 31 - Related articles - BL Direct - All 4 versions
PE Sax, P Kumar - JAIDS Journal of Acquired Immune Deficiency …, 2004 - journals.lww.com Summary: Antiretroviral drugs are associated with both short-term and long-term adverse
events. Like other HIV drugs, protease inhibi- tors (PIs) may affect metabolic processes influencing
body shape and body tissue composition, appearance, bone integrity, and cardiovas- ... Cited by 31 - Related articles - BL Direct - All 8 versions
