- ►angrylapdog.com AJ van der Lely, M Tschop, ML … - Endocrine …, 2004 - edrv.endojournals.org.p. … Ghrelin is a peptide predominantly produced by the stomach. Ghrelin displays strong GH-releasing
activity. This activity is mediated by the activation of the so-called GH secretagogue receptor
type 1a. This receptor had been shown to be specific for a family of synthetic, peptidyl and ... Cited by 428 - Related articles - BL Direct - All 9 versions
M Korbonits, AP Goldstone, M Gueorguiev, AB … - Frontiers in …, 2004 - Elsevier Ghrelin is brain-gut peptide with growth hormone-releasing and appetite-inducing activities.
It is mainly secreted from the stomach mucosa but it is also expressed widely in different tissues
and therefore may have both endocrine and paracrine effects. Ghrelin is the endogenous ... Cited by 225 - Related articles - All 4 versions
- ►leptinresearch.org [PDF] A Sahu - Frontiers in neuroendocrinology, 2003 - Elsevier Leptin, the long-sought satiety factor of adipocytes origin, has emerged as one of the major signals
that relay the status of fat stores to the hypothalamus and plays a significant role in energy
homeostasis. Understanding the mechanisms of leptin signaling in the hypothalamus ... Cited by 128 - Related articles - All 7 versions
DE Cummings - Physiology & behavior, 2006 - Elsevier Ghrelin, an acylated upper gastrointestinal peptide, is the only known orexigenic hormone. Considerable
evidence implicates ghrelin in mealtime hunger and meal initiation. Circulating levels decrease
with feeding and increase before meals, achieving concentrations sufficient to stimulate ... Cited by 118 - Related articles - All 4 versions
- ►fasebj.org A INUI, A ASAKAWA, CY BOWERS, G MANTOVANI, A … - The FASEB Journal, 2004 - FASEB Recent progress in the field of energy homeostasis was triggered by the discovery of adipocyte
hormone leptin and revealed a complex regulatory neuroendocrine network. A late addition is
the novel stomach hormone ghrelin, which is an endogenous agonist at the growth ... Cited by 105 - Related articles - BL Direct - All 5 versions
- ►endojournals.org HS Callahan, DE Cummings, MS Pepe, PA … - Journal of Clinical …, 2004 - Endocrine Soc Plasma ghrelin levels rise before meals and fall rapidly afterward. If ghrelin is a physiological
meal-initiation signal, then a large oral caloric load should suppress ghrelin levels more than
a small caloric load, and the request for a subsequent meal should be predicted by ... Cited by 102 - Related articles - BL Direct - All 5 versions
- ►endojournals.org A Sahu - Endocrinology, 2004 - Endocrine Soc The hypothalamus is a major site for integration of central and peripheral signals that regulate
energy homeostasis. Within the hypothalamus, neurons residing in the ARC (arcuate
nucleus)-PVN (paraventricular)-PF/LH (perifornical/lateral hypothalamus) axis ... Cited by 90 - Related articles - BL Direct - All 8 versions
MD Klok, S Jakobsdottir, ML Drent… - Obesity reviews, 2007 - interscience.wiley.com Leptin and ghrelin are two hormones that have been recognized to have a major influence on
energy balance. Leptin is a mediator of long-term regulation of energy balance, suppressing
food intake and thereby inducing weight loss. Ghrelin on the other hand is a fast-acting ... Cited by 88 - Related articles - BL Direct - All 2 versions
E Ghigo, F Broglio, E Arvat, M Maccario, M Papotti … - Clinical …, 2005 - medscape.com Ghrelin, an acylated peptide produced predominantly by the stomach, has been discovered to
be a natural ligand of the growth hormone secretagogue receptor type 1a (GHS-R1a). Ghrelin
has recently attracted considerable interest as a new orexigenic factor. However, ghrelin ... Cited by 82 - Related articles - All 9 versions
DE Cummings, KE Foster-Schubert, J … - Current Drug Targets, 2005 - ingentaconnect.com Abstract: Ghrelin is an enteric peptide that is the only known circulating appetite stimulant. This
feature of the hormone has garnered widespread attention, as reflected by more than 1000 scientific
papers featuring ghrelin that have been published since the first reports of its orexigenic ... Cited by 79 - Related articles - All 3 versions
