- ►endojournals.org I Kharroubi, L Ladriere, AK Cardozo, Z Dogusan, M … - Endocrinology, 2004 - Endocrine Soc Apoptosis is probably the main form of ß-cell death in both type 1 diabetes mellitus (T1DM) and
T2DM. In T1DM, cytokines contribute to ß-cell destruction through nuclear factor- B (NF- B)
activation. Previous studies suggested that in T2DM high glucose and free fatty acids ... Cited by 136 - Related articles - BL Direct - All 3 versions
- ►jbc.org S Hardy, W El-Assaad, E Przybytkowski, E Joly, M … - Journal of Biological …, 2003 - ASBMB Little is known about the biochemical basis of the action of free fatty acids (FFA) on breast cancer
cell proliferation and apoptosis. Here we report that unsaturated FFAs stimulated the proliferation
of human MDA-MB-231 breast cancer cells, whereas saturated FFAs inhibited it and ... Cited by 101 - Related articles - BL Direct - All 4 versions
- ►fasebj.org [PDF] M Artwohl, M Roden, W Waldhausl, A Freudenthaler, … - The FASEB Journal, 2003 - FASEB Page 1. The FASEB Journal express article 10.1096/fj.03-0301fje. Published online
November 3, 2003. Free fatty acids trigger apoptosis and inhibit cell cycle progression
in human vascular endothelial cells Michaela Artwohl ... Cited by 84 - Related articles - BL Direct - All 5 versions
C Weigert, K Brodbeck, H Staiger, C Kausch, F … - Journal of Biological …, 2004 - ASBMB Circulating interleukin-6 (IL-6), insulin, and free fatty acid (FFA) concentrations are associated
with impaired insulin action in obese and type 2 diabetic individuals. However, a causal relationship
between elevated plasma FFAs and IL-6 has not been shown. Because skeletal muscle ... Cited by 84 - Related articles - BL Direct - All 4 versions
H Staiger, S Kaltenbach, K Staiger, N Stefan, A Fritsche … - Diabetes, 2004 - Am Diabetes Assoc The adiponectin receptors, AdipoR1 and AdipoR2, are thought to transmit the
insulin-sensitizing, anti-inflammatory, and atheroprotective effects of adiponectin. In this
study, we examined whether AdipoR mRNA expression in human myotubes correlates ... Cited by 75 - Related articles - BL Direct - All 4 versions
- ►nutrition.org KM Ajuwon, ME Spurlock - Journal of Nutrition, 2005 - Am Soc Nutrition Fatty acids and their metabolites regulate gene expression and immunological pathways.
Furthermore, obese individuals frequently have increased circulating fatty acid
concentrations, and localized inflammation in adipose tissue may facilitate the systemic ... Cited by 65 - Related articles - BL Direct - All 3 versions
- ►nih.gov R Park, JD Baines - Journal of virology, 2006 - Am Soc Microbiol We report that herpes simplex virus type 1 (HSV-1) infection leads to the recruitment of protein
kinase C (PKC) to the nuclear rim. In HEp-2 cells, PKC recruitment to the nuclear rim was initiated
between 8 h and 12 h postinfection. PKC , a proapoptotic kinase, was completely ... Cited by 39 - Related articles - BL Direct - All 9 versions
QF Collins, Y Xiong, EG Lupo, HY Liu, W Cao - Journal of Biological Chemistry, 2006 - ASBMB Free fatty acids (FFA) are considered as a causative link between obesity and diabetes. In various
animal models and in humans FFA can stimulate hepatic gluconeogenesis. Although the in vivo
role of FFA in hepatic gluconeogenesis has been clearly established, the intracellular role ... Cited by 38 - Related articles - All 6 versions
- ►jbc.org C Weigert, AM Hennige, R Lehmann, K Brodbeck, F … - Journal of Biological …, 2006 - ASBMB The exercise-induced interleukin (IL)-6 production and secretion within skeletal muscle fibers
has raised the question of a putative tissue-specific function of IL-6 in the energy metabolism
of the muscle during and after the exercise. In the present study, we followed the ... Cited by 37 - Related articles - BL Direct - All 6 versions
- ►diabetesjournals.org H Staiger, K Staiger, N Stefan, HG Wahl, F Machicao, M … - Diabetes, 2004 - Am Diabetes Assoc Obesity-linked insulin resistance is associated with chronic inflammation and cardiovascular
complications. Free fatty acids (FFAs) are prominent candidates for the molecular link between
these disorders. In this study, we determined whether FFAs contribute to vascular ... Cited by 37 - Related articles - BL Direct - All 5 versions
