B Wicksteed, C Alarcon, I Briaud, MK Lingohr … - Journal of Biological Chemistry, 2003 - ASBMB Proinsulin biosynthesis is regulated in response to nutrients, most notably
glucose. In the short term ( 2h) this is due to increases in the translation of
pre-existing mRNA. However, prolonging glucose stimulation (24 h) also ... Cited by 61 - Related articles - BL Direct - All 4 versions
- ►physiology.org K Otani, RN Kulkarni, AC Baldwin, J … - American Journal of Physiology- Endocrinology And …, 2004 - Am Physiological Soc Pancreatic -cell-restricted knockout of the insulin receptor results in
hyperglycemia due to impaired insulin secretion, suggesting that this cell is an
important target of insulin action. The present studies were undertaken in ... Cited by 60 - Related articles - BL Direct - All 3 versions
RN Kulkarni - Reviews in Endocrine & Metabolic Disorders, 2005 - Springer Page 1. Reviews in Endocrine & Metabolic Disorders 2005;6:199–210 C 2005 Springer
Science + Business Media, Inc. Manufactured in The Netherlands. ... Cited by 34 - Related articles - BL Direct - All 3 versions
- ►diabetesjournals.org N Kaiser, R Nesher, MY Donath, M Fraenkel, V … - Diabetes, 2005 - Am Diabetes Assoc Type 2 diabetes is characterized by insulin resistance and progressive ß-cell
failure. Deficient insulin secretion, with increased proportions of insulin
precursor molecules, is a common feature of type 2 diabetes; this could ... Cited by 26 - Related articles - BL Direct - All 6 versions
D Muller, GC Huang, S Amiel, PM Jones, SJ … - Diabetes, 2006 - Am Diabetes Assoc Although many studies using rodent islets and insulinoma cell lines have been
performed to determine the role of insulin in the regulation of islet function,
the autocrine effect of insulin on insulin gene expression is still ... Cited by 25 - Related articles - BL Direct - All 4 versions
- ►diabetesjournals.org HA Russ, Y Bar, P Ravassard, S Efrat - Diabetes, 2008 - Am Diabetes Assoc RESULTS— β-Cells were efficiently and specifically labeled by the dual virus
system. Label + , insulin − cells derived from β-cells were shown to
proliferate for a maximum of 16 population doublings, with an approximate ... Cited by 19 - Related articles - All 4 versions
G Leibowitz, MZ Khaldi, A Shauer, M Parnes, … - Diabetologia, 2005 - Springer Page 1. Diabetologia (2005) 48: 1549–1559 DOI 10.1007/s00125-005-1811-6 ARTICLE
G. Leibowitz . MZ Khaldi . A. Shauer . M. Parnes . AI Oprescu . E. Cerasi . ... Cited by 9 - Related articles - BL Direct - All 4 versions
V Attali, M Parnes, Y Ariav, E Cerasi, N Kaiser … - Endocrinology, 2006 - Endocrine Soc Succinate stimulates insulin secretion and proinsulin biosynthesis. We studied
the effects of reduced nicotinamide adenine dinucleotide phosphate
(NADPH)-modulating pathways on glucose- and succinate-stimulated insulin ... Cited by 5 - Related articles - BL Direct - All 4 versions
H Ortsater, P Bergsten - Expert Review of Proteomics, 2006 - ingentaconnect.com The insulin-producing β cell in the islet of Langerhans is central in glucose
homeostasis. Its dysfunction is part of the pathogenesis of both Type 1 and 2
diabetes mellitus. In both forms of the disease, there is a cytotoxic ... Cited by 5 - Related articles - BL Direct - All 4 versions
