- ►rh.dk [PDF] LL Baggio, DJ Drucker - Gastroenterology, 2007 - Elsevier This review focuses on the mechanisms regulating the synthesis, secretion,
biological actions, and therapeutic relevance of the incretin peptides
glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like ... Cited by 179 - Related articles - All 25 versions
- ►stanford.edu [PDF] MK Badman, JS Flier - Science, 2005 - sciencemag.org In addition to digesting and assimilating nutrients, the intestine and
associated visceral organs play a key sensing and signaling role in the
physiology of energy homeostasis. The gut, the pancreatic islets of ... Cited by 162 - Related articles - All 14 versions
- ►nih.gov DE Cummings, J Overduin - Journal of Clinical Investigation, 2007 - Am Soc Clin Investig Despite substantial fluctuations in daily food intake, animals maintain a
remarkably stable body weight, because overall caloric ingestion and expenditure
are exquisitely matched over long periods of time, through the process of ... Cited by 152 - Related articles - BL Direct - All 10 versions
- ►nih.gov FM Ashcroft - Journal of Clinical Investigation, 2005 - Am Soc Clin Investig ATP-sensitive potassium (K ATP ) channels, so named because they are inhibited
by intracellular ATP , play key physiological roles in many tissues. In
pancreatic β cells, these channels regulate glucose-dependent insulin ... Cited by 142 - Related articles - BL Direct - All 14 versions
AT Hattersley, FM Ashcroft - Diabetes, 2005 - Am Diabetes Assoc Closure of ATP-sensitive K + channels (K ATP channels) in response to
metabolically generated ATP or binding of sulfonylurea drugs stimulates insulin
release from pancreatic β-cells. Heterozygous gain-of-function mutations ... Cited by 138 - Related articles - BL Direct - All 10 versions
- ►physiology.org JJ Holst - Physiological reviews, 2007 - Am Physiological Soc Glucagon-like peptide 1 (GLP-1) is a 30-amino acid peptide hormone produced in
the intestinal epithelial endocrine L-cells by differential processing of
proglucagon, the gene which is expressed in these cells. The current ... Cited by 119 - Related articles - BL Direct - All 5 versions
FM Gribble, F Reimann - Diabetologia, 2003 - Springer Hypoglycaemic agents such as sulphonylureas and the newer group of
“glinides” stimulate insulin secretion by closing ATP-sensitive potassium (K
ATP ) channels in pancreatic beta cells, but have varying cross-reac- ... Cited by 107 - Related articles - BL Direct - All 3 versions
- ►pnas.org A Díez-Sampedro, BA Hirayama, C Osswald, V … - Proceedings of the National Academy of Sciences, 2003 - National Acad Sciences We have examined the expression and function of a previously undescribed human
member (SGLT3/SLC5A4) of the sodium/glucose cotransporter gene family (SLC5)
that was first identified by the chromosome 22 genome project. The cDNA was ... Cited by 88 - Related articles - BL Direct - All 10 versions
CF Deacon - Regulatory peptides, 2005 - Elsevier The incretin hormones, glucose-dependent insulinotropic peptide (GIP) and
glucagon-like peptide-1 (GLP-1) are secreted from endocrine cells located in the
intestinal mucosa, and act to enhance meal-induced insulin secretion. GIP ... Cited by 70 - Related articles - All 6 versions
A Patriti, E Facchiano, A Sanna, N Gulla, A … - Obesity surgery, 2004 - Springer The Roux-en-Y gastric bypass (RYGBP) and the bil- iopancreatic diversion (BPD)
induce long-term con- trol of type 2 diabetes in morbidly obese individuals. The
reasons for such an effect on glycemic metabo- lism are thought to be ... Cited by 70 - Related articles - BL Direct - All 5 versions
