A Wendt, B Birnir, K Buschard, J Gromada, A … - Diabetes, 2004 - Am Diabetes Assoc Outside the CNS, GABA and GAD, the enzyme catalyzing the formation of the
neurotransmitter, are present at high levels in the pancreatic β-cells (2,3).
GAD65 is the most abundant, if not the only, isoform of GAD in human islets ... Cited by 84 - Related articles - BL Direct - All 4 versions
I Franklin, J Gromada, A Gjinovci, S … - Diabetes, 2005 - Am Diabetes Assoc Glucagon, secreted from islet α-cells, mobilizes liver glucose. During
hyperglycemia, glucagon secretion is inhibited by paracrine factors from other
islet cells, but in type 1 and type 2 diabetic patients, this suppression ... Cited by 74 - Related articles - All 4 versions
- ►diabetesjournals.org J Gromada, X Ma, M Høy, K Bokvist, A … - Diabetes, 2004 - Am Diabetes Assoc Patch-clamp recordings and glucagon release measurements were combined to
determine the role of plasma membrane ATP-sensitive K + channels (K ATP
channels) in the control of glucagon secretion from mouse pancreatic ... Cited by 59 - Related articles - BL Direct - All 5 versions
- ►endojournals.org J Gromada, I Franklin, CB Wollheim - Endocrine reviews, 2007 - Endocrine Soc Glucagon, a hormone secreted from the -cells of the endocrine pancreas, is
critical for blood glucose homeostasis. It is the major counterpart to insulin
and is released during hypoglycemia to induce hepatic glucose output. The ... Cited by 60 - Related articles - BL Direct - All 4 versions
- ►nih.gov KW Sloop, JXC Cao, AM Siesky, HY Zhang, DM … - Journal of Clinical Investigation, 2004 - Am Soc Clin Investig Uncontrolled hepatic glucose production contributes significantly to
hyperglycemia in patients with type 2 diabetes. Hyperglucagonemia is implicated
in the etiology of this condition; however, effective therapies to block ... Cited by 46 - Related articles - BL Direct - All 6 versions
- ►endojournals.org HL Olsen, S Theander, K Bokvist, K Buschard … - Endocrinology, 2005 - Endocrine Soc In isolated rat pancreatic -cells, glucose, arginine, and the sulfonylurea
tolbutamide stimulated glucagon release. The effect of glucose was abolished by
the K ATP -channel opener diazoxide as well as by mannoheptulose and azide, ... Cited by 43 - Related articles - BL Direct - All 5 versions
- ►endojournals.org BE Dunning, JE Gerich - Endocrine reviews, 2007 - Endocrine Soc The hyperglycemic activity of pancreatic extracts was encountered some 80 yr ago
during efforts to optimize methods for the purification of insulin. The
hyperglycemic substance was named "glucagon," and it was subsequently ... Cited by 32 - Related articles - BL Direct - All 5 versions
Q Zhang, JR Davenport, MJ Croyle, CJ … - Laboratory Investigation, 2005 - assets0.pubget.com While relatively ignored for years as vestigial, cilia have recently become the
focus of intense interest as organelles that result in severe pathologies when
disrupted. Here, we further establish a connection between cilia ... Cited by 31 - Related articles - View as HTML - All 4 versions
E Vieira, A Salehi, E Gylfe - Diabetologia, 2007 - Springer Abstract Aims/hypothesis The mechanisms by which glucose regu- lates glucagon
release are poorly understood. The present study aimed to clarify the direct
effects of glucose on the glucagon-releasing alpha cells and those effects ... Cited by 23 - Related articles - BL Direct - All 4 versions
