- ►shouxi.net PE Cryer - New England Journal of Medicine, 2004 - content.nejm.org In this article, I discuss the clinical problem of hypoglycemia in diabetes from the perspective
of pathophysiology. First, the syndromes of defective glucose counterregulation and hypoglycemia
without warning symptoms (known as "hypoglycemia unawareness") are described, ... Cited by 156 - Related articles - BL Direct - All 6 versions
PE Cryer - Diabetes, 2005 - Am Diabetes Assoc Iatrogenic hypoglycemia is a problem for people with diabetes. It causes recurrent morbidity,
and sometimes death, as well as a vicious cycle of recurrent hypoglycemia, precluding maintenance
of euglycemia over a lifetime of diabetes. Improved therapeutic approaches that will ... Cited by 75 - Related articles - BL Direct - All 7 versions
MF Dallman, SF Akana, AM Strack, KS … - ANNALS-NEW …, 2004 - interscience.wiley.com Abstract: Acutely, glucocorticoids act to inhibit stress-induced corticotrophin-releasing factor
(CRF) and adrenocorticotrophic hormone (ACTH) secretion through their actions in brain and
anterior pituitary (canonical feedback). With chronic stress, glucocorticoid feedback ... Cited by 46 - Related articles - BL Direct - All 6 versions
TW Jones, EA Davis - Pediatric Diabetes, 2003 - interscience.wiley.com Abstract: Hypoglycemia is a common complication of insulin therapy, particularly in the
young. For children and adolescents with diabetes, the risk of hypoglycemia may not only prevent
optimal glycemic control but can also add significantly to the psychosocial burden of the ... Cited by 32 - Related articles - BL Direct - All 3 versions
PE Cryer - Progress in Brain Research, 2006 - Elsevier Iatrogenic hypoglycemia, the limiting factor in the glycemic management of diabetes, causes
recurrent morbidity (and sometimes death), precludes maintenance of euglycemia over a lifetime
of diabetes and causes a vicious cycle of recurrent hypoglycemia. In insulin deficient — ... Cited by 25 - Related articles - BL Direct - All 4 versions
KV Allen, BM Frier - Endocrine Practice, 2003 - AACE Strict control of blood glucose has been shown to pre- vent the development and to delay the
progression of the vascular and neuropathic complications of type 1 and type 2 diabetes
(1-3). Strict glycemic control, however, is asso- ciated with an increased risk of exposure ... Cited by 26 - Related articles - BL Direct - All 2 versions
B Raju, VP McGregor, PE Cryer - Diabetes, 2003 - Am Diabetes Assoc The concept of hypoglycemia-associated autonomic failure (HAAF) in diabetes posits that recent
antecedent iatrogenic hypoglycemia causes both defective glucose counterregulation (by reducing
the epinephrine response in the setting of an absent glucagon response) and ... Cited by 22 - Related articles - BL Direct - All 4 versions
- ►endojournals.org B Raju, AM Arbelaez, SM Breckenridge, PE … - Journal of Clinical …, 2006 - Endocrine Soc Results: In the absence of a bedtime treatment, 27% of the measured nocturnal plasma glucose
concentrations were less than 70 mg/dl (3.9 mmol/liter) in 12 patients; 16, 6, and 1% were less
than 60, less than 50, and less than 40 mg/dl (3.3, 2.8, and 2.2 mmol/liter), respectively. ... Cited by 21 - Related articles - BL Direct - All 4 versions
- ►rh.dk [PDF] PE Cryer - Diabetologia, 2006 - Springer In 2001, Van den Berghe and colleagues [1] reported reduced mortality and morbidity in patients
admitted to the surgical intensive care unit (ICU) who were randomly assigned to intensive insulin
therapy (n=765). This was initiated when blood glucose was >6.1 mmol/l (110 mg/dl), with ... Cited by 24 - Related articles - BL Direct - All 5 versions
- ►diabetesjournals.org PE Cryer - Diabetes, 2008 - Am Diabetes Assoc Glycemic control, a worthwhile goal for people with diabetes, is limited by the barrier of iatrogenic
hypoglycemia (1). Iatrogenic hypoglycemia 1) causes recurrent morbidity in most people with
type 1 diabetes and many with advanced type 2 diabetes and is sometimes fatal, 2) ... Cited by 16 - Related articles - All 3 versions
