MR Loeken - American Journal of Medical Genetics Part C Seminars …, 2005 - interscience.wiley.com It is also possible that your web browser is not configured or not able to
display style sheets. In this case, although the visual presentation will be
degraded, the site should continue to be functional. We recommend using the ... Cited by 32 - Related articles - All 4 versions
- ►physiology.org R Li, M Chase, SK Jung, PJS Smith, MR … - American Journal of Physiology- Endocrinology And …, 2005 - Am Physiological Soc We have shown that neural tube defects (NTD) in a mouse model of diabetic
embryopathy are associated with deficient expression of Pax3, a gene required
for neural tube closure. Hyperglycemia-induced oxidative stress is ... Cited by 30 - Related articles - BL Direct - All 9 versions
MR Loeken - Journal of Maternal-Fetal and Neonatal Medicine, 2004 - informahealthcare.com Maternal diabetes significantly increases the risk for birth defects. Studies
using animal models indicate that oxidative stress may play a causative role.
Oxidative stress can result from exposure to certain drugs, ionizing ... Cited by 23 - Related articles - BL Direct - All 6 versions
- ►shouxi.net JK Riley, MO Carayannopoulos, AH Wyman, M … - Journal of Biological Chemistry, 2006 - ASBMB The phosphatidylinositol 3-kinase (PI3K) signal transduction pathway is a well
known mediator of cell growth, proliferation, and survival signals. Whereas the
expression and function of this pathway has been documented during ... Cited by 21 - Related articles - BL Direct - All 7 versions
- ►reproduction-online.org JK Riley, KH Moley - Reproduction, 2006 - Soc Reprod Fertility The maintenance of optimal glucose utilization during the preimplantation period
is critical for embryo survival. A decrease in glucose transport during
preimplantation development has been linked to the early steps of ... Cited by 22 - Related articles - BL Direct - All 4 versions
M Gäreskog, J Cederberg, UJ Eriksson, P … - Reproductive Toxicology, 2007 - Elsevier We found decreased Bcl-2, increased Bax and cleaved Caspase 3 proteins in
embryos from diabetic rats. Moreover, we found increased activation of Caspase 3
in cells from embryos previously exposed to a diabetes-like environment (in ... Cited by 16 - Related articles - All 4 versions
R Klaper, CB Rees, P Drevnick, D Weber, M … - Environmental health perspectives, 2006 - pubmedcentral.nih.gov Results. Expression of genes commonly associated with endocrine disruption was
altered with Hg exposure. Specifically, we observed a marked up-regulation in
vitellogenin mRNA in individual Hg-exposed males and a significant decline ... Cited by 15 - Related articles - BL Direct - All 18 versions
S Akazawa - Congenital Anomalies, 2005 - interscience.wiley.com In a diabetic environment, hyperglycemia caused an increased glucose flux into
embryonic cells without a down-regulation of GLUT1 and an increased metabolic
overload on mitochondria, leading to an increased formation of reactive ... Cited by 14 - Related articles - BL Direct - All 5 versions
J Han, J Xu, PN Epstein, YQ Liu - Diabetologia, 2005 - Springer Abstract Aim/hypothesis: Obesity is a global problem with high risks of
cardiovascular diseases, stroke and type 2 diabetes. It is well known that
maternal obesity affects offspring by inducing malformation, functional ... Cited by 13 - Related articles - BL Direct - All 4 versions
- ►clevelandclinic.org [PDF] RK Sharma, A Agarwal - Reproductive Medicine and Biology, 2004 - Springer Free radicals derived from molecular oxygen and nitrogen are highly reactive
metabolites called reactive oxygen species (ROS). Cells continuously produce
free radicals and ROS as part of the metabolic process. They are involved ... Cited by 13 - Related articles - All 8 versions
