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Scholar Results 1 - 10 of about 28 citing Roy: Downregulation of fibronectin overexpression reduces basement membrane thickening and.... (0.10 sec) 

Differential expression of connective tissue growth factor in microglia and pericytes …


EJ Kuiper, AN Witmer, I Klaassen, N Oliver, R … - British Journal of …, 2004 - bjo.bmj.com
Results: In the retina, distinct and specific staining of CTGF was observed in microglia, situated
around or in close vicinity of retinal capillaries. In the control cases, sporadic staining of pericytes
was also observed within the vascular wall. In contrast, in the retina of people with ...
Cited by 27 - Related articles - BL Direct - All 12 versions

Age-dependent remodeling of connective tissue: role of fibronectin and laminin


J Labat-Robert - Pathologie Biologie, 2003 - Elsevier
Connective tissues differ from other tissues in their more abundant extracellular matrix
(ECM). This matrix is composed of a relatively large number of macromolecules interacting with
each other as well as with the cells they are surrounding. Such cells, fibroblasts, ...
Cited by 19 - Related articles - All 4 versions

Advanced glycation end products cause increased CCN family and extracellular …

- nih.gov
JM Hughes, EJ Kuiper, I Klaassen, P Canning, AW Stitt, … - Diabetologia, 2007 - Springer
Page 1. ARTICLE Advanced glycation end products cause increased CCN family
and extracellular matrix gene expression in the diabetic rodent retina JM Hughes
& EJ Kuiper & I. Klaassen & P. Canning & AW Stitt & J. Van Bezu ...
Cited by 18 - Related articles - BL Direct - All 7 versions

Effect of Combined Antisense Oligonucleotides Against High-Glucose–and …


T Oshitari, P Polewski, M Chadda, AF Li, T Sato, S Roy - Diabetes, 2006 - Am Diabetes Assoc
The effect of combined antisense oligonucleotides (AS-oligos) against overexpression of extracellular
matrix (ECM) components, fibronectin, laminin, and collagen IV and on cell monolayer permeability
was examined in rat microvascular endothelial cells (RMECs) grown in high glucose ...
Cited by 17 - Related articles - BL Direct - All 7 versions

Diabetes: a potential enhancer of retinal injury in rat retinas


T Oshitari, S Roy - Neuroscience letters, 2005 - Elsevier
This study was performed to determine whether early diabetes accelerates retinal neuronal cell
death and inhibits neurite regeneration. Five of ten rats were rendered diabetic with streptozotocin
injection. After 3 weeks of diabetes, retinas were isolated and retinal explants were ...
Cited by 14 - Related articles - All 3 versions

Diabetes-Enhanced Tumor Necrosis Factor-{alpha} Production Promotes …

- amjpathol.org
Y Behl, P Krothapalli, T Desta, A DiPiazza, S Roy, DT … - American Journal of …, 2008 - ASIP
Retinal microvascular cell loss plays a critical role in the pathogenesis of diabetic
retinopathy. To examine this further, type 1 streptozotocin-induced diabetic rats and type 2 Zucker
diabetic fatty rats were treated by intravitreal injection of the tumor necrosis factor-specific ...
Cited by 10 - Related articles - BL Direct - All 6 versions

Effect of VEGF-A on expression of profibrotic growth factor and extracellular matrix …

- iovs.org
EJ Kuiper, JM Hughes, RJ Van Geest, I Vogels, R … - … Ophthalmology & Visual …, 2007 - ARVO
PURPOSE. Vascular endothelial growth factor-A (VEGF) causes increased vascular permeability
and leukocyte adhesion in preclinical diabetic retinopathy (PCDR). Another hallmark of PCDR
is thickening of the capillary basement membrane (BM). Recently, VEGF has been shown ...
Cited by 9 - Related articles - BL Direct - All 2 versions

[PDF] Cellular signaling and potential new treatment targets in diabetic retinopathy


ZA Khan, S Chakrabarti - Exp Diabetes Res, 2007 - hindawi.com
Dysfunction and death of microvascular cells and imbalance between the production and the
degradation of extracellular matrix (ECM) proteins are a characteristic feature of diabetic retinopathy
(DR). Glucose-induced biochemical alterations in the vascu- lar endothelial cells may ...
Cited by 8 - Related articles - View as HTML - All 15 versions

Fibrosis in diabetes complications: Pathogenic mechanisms and circulating and …


CR Ban, SM Twigg - Vascular Health and Risk Management, 2008 - pubmedcentral.nih.gov
Diabetes mellitus is characterized by a lack of insulin causing elevated blood glucose, often
with associated insulin resistance. Over time, especially in genetically susceptible
individuals, such chronic hyperglycemia can cause tissue injury. One pathological ...
Cited by 7 - Related articles - All 8 versions

Arachidonic acid as a retrograde signal controlling growth and dynamics of …


BH Leu, JT Schmidt - Journal of Neurobiology - interscience.wiley.com
In the developing visual system, correlated presynaptic activity between neighboring retinal ganglion
cells (RGC) stabilizes retinotopic synapses via a postsynaptic NMDAR (N-methyl-D-aspartate
receptor)-dependent mechanism. Blocking NMDARs makes individual axonal arbors ...
Cited by 6 - Related articles - BL Direct - All 2 versions


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