EJ Kuiper, AN Witmer, I Klaassen, N Oliver, R … - British Journal of …, 2004 - bjo.bmj.com Results: In the retina, distinct and specific staining of CTGF was observed in microglia, situated
around or in close vicinity of retinal capillaries. In the control cases, sporadic staining of pericytes
was also observed within the vascular wall. In contrast, in the retina of people with ... Cited by 27 - Related articles - BL Direct - All 12 versions
J Labat-Robert - Pathologie Biologie, 2003 - Elsevier Connective tissues differ from other tissues in their more abundant extracellular matrix
(ECM). This matrix is composed of a relatively large number of macromolecules interacting with
each other as well as with the cells they are surrounding. Such cells, fibroblasts, ... Cited by 19 - Related articles - All 4 versions
- ►nih.gov JM Hughes, EJ Kuiper, I Klaassen, P Canning, AW Stitt, … - Diabetologia, 2007 - Springer Page 1. ARTICLE Advanced glycation end products cause increased CCN family
and extracellular matrix gene expression in the diabetic rodent retina JM Hughes
& EJ Kuiper & I. Klaassen & P. Canning & AW Stitt & J. Van Bezu ... Cited by 18 - Related articles - BL Direct - All 7 versions
T Oshitari, P Polewski, M Chadda, AF Li, T Sato, S Roy - Diabetes, 2006 - Am Diabetes Assoc The effect of combined antisense oligonucleotides (AS-oligos) against overexpression of extracellular
matrix (ECM) components, fibronectin, laminin, and collagen IV and on cell monolayer permeability
was examined in rat microvascular endothelial cells (RMECs) grown in high glucose ... Cited by 17 - Related articles - BL Direct - All 7 versions
T Oshitari, S Roy - Neuroscience letters, 2005 - Elsevier This study was performed to determine whether early diabetes accelerates retinal neuronal cell
death and inhibits neurite regeneration. Five of ten rats were rendered diabetic with streptozotocin
injection. After 3 weeks of diabetes, retinas were isolated and retinal explants were ... Cited by 14 - Related articles - All 3 versions
- ►amjpathol.org Y Behl, P Krothapalli, T Desta, A DiPiazza, S Roy, DT … - American Journal of …, 2008 - ASIP Retinal microvascular cell loss plays a critical role in the pathogenesis of diabetic
retinopathy. To examine this further, type 1 streptozotocin-induced diabetic rats and type 2 Zucker
diabetic fatty rats were treated by intravitreal injection of the tumor necrosis factor-specific ... Cited by 10 - Related articles - BL Direct - All 6 versions
- ►iovs.org EJ Kuiper, JM Hughes, RJ Van Geest, I Vogels, R … - … Ophthalmology & Visual …, 2007 - ARVO PURPOSE. Vascular endothelial growth factor-A (VEGF) causes increased vascular permeability
and leukocyte adhesion in preclinical diabetic retinopathy (PCDR). Another hallmark of PCDR
is thickening of the capillary basement membrane (BM). Recently, VEGF has been shown ... Cited by 9 - Related articles - BL Direct - All 2 versions
ZA Khan, S Chakrabarti - Exp Diabetes Res, 2007 - hindawi.com Dysfunction and death of microvascular cells and imbalance between the production and the
degradation of extracellular matrix (ECM) proteins are a characteristic feature of diabetic retinopathy
(DR). Glucose-induced biochemical alterations in the vascu- lar endothelial cells may ... Cited by 8 - Related articles - View as HTML - All 15 versions
CR Ban, SM Twigg - Vascular Health and Risk Management, 2008 - pubmedcentral.nih.gov Diabetes mellitus is characterized by a lack of insulin causing elevated blood glucose, often
with associated insulin resistance. Over time, especially in genetically susceptible
individuals, such chronic hyperglycemia can cause tissue injury. One pathological ... Cited by 7 - Related articles - All 8 versions
BH Leu, JT Schmidt - Journal of Neurobiology - interscience.wiley.com In the developing visual system, correlated presynaptic activity between neighboring retinal ganglion
cells (RGC) stabilizes retinotopic synapses via a postsynaptic NMDAR (N-methyl-D-aspartate
receptor)-dependent mechanism. Blocking NMDARs makes individual axonal arbors ... Cited by 6 - Related articles - BL Direct - All 2 versions