- ►case.edu [PDF] L Pirola, AM Johnston, EV Obberghen - Diabetologia, 2004 - Springer Insulin is a key hormone regulating the control of metabolism and the
maintenance of normoglycaemia and normolipidaemia. Insulin acts by binding to
its cell surface receptor, thus activating the receptor's intrinsic ... Cited by 134 - Related articles - BL Direct - All 6 versions
- ►diabetesjournals.org FB Stentz, GE Umpierrez, R Cuervo, AE … - Diabetes, 2004 - Am Diabetes Assoc Acute and chronic hyperglycemia are proinflammatory states, but the status of
proinflammatory cytokines and markers of oxidative stress and cardiovascular
risks is not known in hyperglycemic crises of diabetic ketoacidosis (DKA) ... Cited by 131 - Related articles - BL Direct - All 4 versions
H Kolb, T Mandrup-Poulsen - Diabetologia, 2005 - Springer Abstract Subclinical, low-grade systemic inflammation has been observed in
patients with type 2 diabetes and in those at increased risk of the disease.
This may be more than an epiphenomenon. Alleles of genes encoding immune/ ... Cited by 116 - Related articles - BL Direct - All 5 versions
T Doenst, D Wijeysundera, K Karkouti, C … - The Journal of Thoracic and Cardiovascular Surgery, 2005 - Elsevier Hyperglycemia is commonly present in the perioperative period in patients
undergoing cardiac surgery, even during administration of insulin. A direct
relationship between postoperative hyperglycemia and mortality has been ... Cited by 89 - Related articles - All 12 versions
N Shanmugam, YS Kim, L Lanting, R … - Journal of Biological Chemistry, 2003 - ASBMB Cyclooxygenase-2 (COX-2) enzyme and its inflammatory products such as
prostaglandin E 2 (PGE 2 ) have been implicated in the pathogenesis of several
inflammatory diseases. However their role in diabetic vascular disease is ... Cited by 80 - Related articles - BL Direct - All 4 versions
- ►ahajournals.org R Natarajan, JL Nadler - Arteriosclerosis, thrombosis, and vascular biology, 2004 - Am Heart Assoc Type 2 diabetes is associated with significantly accelerated rates of
macrovascular complications such as atherosclerosis. Emerging evidence now
indicates that atherosclerosis is an inflammatory disease and that certain ... Cited by 78 - Related articles - BL Direct - All 8 versions
- ►diabetesjournals.org S Devaraj, SK Venugopal, U Singh, I Jialal - Diabetes, 2005 - Am Diabetes Assoc Diabetes confers an increased propensity to atherosclerosis. Inflammation is
pivotal in atherogenesis, and diabetes is a proinflammatory state. Interleukin
(IL)-6, in addition to inducing the acute-phase response, contributes to ... Cited by 67 - Related articles - All 5 versions
- ►adisonline.com [PDF] AJ van Oostrom, JPH van Wijk, MC Cabezas - Drugs, 2004 - ingentaconnect.com Abstract Atherosclerosis is the major cause of death in the world. Fasting and
postprandial hyperlipidaemia are important risk factors for coronary heart
disease (CHD). Recent developments have undoubtedly indicated that ... Cited by 56 - Related articles - All 7 versions
- ►jbc.org F Miao, IG Gonzalo, L Lanting, R Natarajan - Journal of Biological Chemistry, 2004 - ASBMB The transcription factor NF- B (NF- B) plays a pivotal role in regulating
inflammatory gene expression. Its effects are optimized by various coactivators
including histone acetyltransferases (HATs) such as CBP/p300 and p/CAF. ... Cited by 59 - Related articles - BL Direct - All 4 versions
E Simeoni, MM Hoffmann, BR Winkelmann, J … - Diabetologia, 2004 - Springer Aims/hypothesis. The molecular mechanisms of obesi- ty-related insulin
resistance are incompletely under- stood. Macrophages accumulate in adipose
tissue of obese individuals. In obesity, monocyte chemoattrac- tant ... Cited by 46 - Related articles - BL Direct - All 7 versions
