- ►cell.com BB Kahn, T Alquier, D Carling, DG Hardie - Cell metabolism, 2005 - Elsevier The AMP-activated protein kinase (AMPK) is an evolutionarily conserved sensor of
cellular energy status, and recent data demonstrate that it also plays a
critical role in systemic energy balance. AMPK integrates nutritional and ... Cited by 641 - Related articles - All 11 versions
- ►endojournals.org T Kadowaki, T Yamauchi - Endocrine Reviews, 2005 - Endocrine Soc Recently, we have cloned adiponectin receptors in the skeletal muscle (AdipoR1)
and liver (AdipoR2), which appear to comprise a novel cell-surface receptor
family. We showed that AdipoR1 and AdipoR2 serve as receptors for globular ... Cited by 625 - Related articles - All 8 versions
H Chen, M Montagnani, T Funahashi, I … - Journal of Biological Chemistry, 2003 - ASBMB Adiponectin is secreted by adipose cells and mimics many metabolic actions of
insulin. However, mechanisms by which adiponectin acts are poorly understood.
The vascular action of insulin to stimulate endothelial production of ... Cited by 450 - Related articles - BL Direct - All 4 versions
- ►harvard.edu [PDF] M Stumvoll, BJ Goldstein, TW van Haeften - The Lancet, 2005 - Elsevier Type 2 diabetes mellitus has become an epidemic, and virtually no physician is
without patients who have the disease. Whereas insulin insensitivity is an early
phenomenon partly related to obesity, pancreas β-cell function declines ... Cited by 433 - Related articles - All 17 versions
- ►endojournals.org BJ Goldstein, R Scalia - Journal of Clinical Endocrinology & Metabolism, 2004 - Endocrine Soc Cardiovascular disease accounts for an overwhelming proportion of the morbidity
and mortality suffered by patients with obesity and type 2 diabetes mellitus,
and recent work has elucidated several potential mechanisms by which ... Cited by 326 - Related articles - BL Direct - All 6 versions
N Ouchi, H Kobayashi, S Kihara, M Kumada, K … - Journal of Biological Chemistry, 2004 - ASBMB Adiponectin is an adipocyte-specific adipocytokine with anti-atherogenic and
anti-diabetic properties. Here, we investigated whether adiponectin regulates
angiogenic processes in vitro and in vivo. Adiponectin stimulated the ... Cited by 269 - Related articles - BL Direct - All 4 versions
R Shibata, N Ouchi, M Ito, S Kihara, I … - Nature medicine, 2004 - kwalshlab.org Patients with diabetes and other obesity-linked conditions have increased
susceptibility to cardiovascular disorders1. The adipocytokine adiponectin is
decreased in patients with obesity- linked diseases2. Here, we found that ... Cited by 241 - Related articles - BL Direct - All 4 versions
- ►endojournals.org AG Pittas, NA Joseph, AS Greenberg - Journal of Clinical Endocrinology & Metabolism, 2004 - Endocrine Soc Insulin resistance is defined as a failure of target organs to respond normally
to the action of insulin. Insulin resistance causes incomplete suppression of
hepatic glucose output and impaired insulin-mediated glucose uptake in the ... Cited by 217 - Related articles - BL Direct - All 4 versions
- ►upenn.edu [PDF] H Motoshima, X Wu, K Mahadev, BJ Goldstein - Biochemical and Biophysical Research …, 2004 - Elsevier Adiponectin (also known as 30-kDa adipocyte complement-related protein or
Acrp30) is an abundant adipocyte-derived plasma protein with
anti-atherosclerotic and insulin-sensitizing properties. In order to ... Cited by 184 - Related articles - All 5 versions
- ►diabetesjournals.org MB Schulze, I Shai, EB Rimm, T Li, N Rifai, … - Diabetes, 2005 - Am Diabetes Assoc Adiponectin, predominantly synthesized in the adipose tissue, seems to have
substantial anti-inflammatory properties and to be a major modulator of insulin
resistance and dyslipidemia, mechanisms that are associated with an ... Cited by 183 - Related articles - All 5 versions
