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Scholar Results 1 - 10 of about 25 citing Sandhu: Low circulating IGF-II concentrations predict weight gain and obesity in humans. (0.14 sec) 

Free insulin-like growth factors–measurements and relationships to growth hormone …


J Frystyk - Growth hormone & IGF research, 2004 - Elsevier
IGF-I is a multipotent growth factor with important actions on normal tissue
growth and regeneration. In addition, IGF-I has been suggested to have
beneficial effects on glucose homeostasis due to its glucose lowering and ...
Cited by 106 - Related articles - All 5 versions

Haplotypic analyses of the IGF2-INS-TH gene cluster in relation to cardiovascular risk traits

- oxfordjournals.org
S Rodriguez, TR Gaunt, SD O'Dell, X Chen, D … - Human Molecular Genetics, 2004 - Oxford Univ Press
The IGF2–INS–TH genomic region has been implicated in various common
disorders including the metabolic syndrome, type 2 diabetes and coronary heart
disease (CHD). Here we present detailed haplotype analysis of 2743 males ...
Cited by 30 - Related articles - BL Direct - All 8 versions

Diabetes and ethnic minorities

- bmj.com
J Oldroyd, M Banerjee, A Heald, K … - British Medical Journal, 2005 - pmj.bmj.com
The global prevalence of diabetes for all age groups is estimated to be 2.8%.
Type 2 diabetes accounts for at least 90% of diabetes worldwide. Diabetes
incidence, prevalence, and disease progression varies by ethnic group. This ...
Cited by 16 - Related articles - BL Direct - All 9 versions

Molecular genetics of human growth hormone, insulin-like growth factors and their …


S Rodriguez, TR Gaunt, INM Day - Human Genetics, 2007 - Springer
Abstract The human growth hormone gene (GH1) and the insulin-like growth factor
1 and 2 genes (IGF1 and IGF2) encode the central elements of a key pathway inXu-
encing growth in humans. This “growth pathway” also includes ...
Cited by 17 - Related articles - All 4 versions

Genetic variation in the type 2 insulin-like growth factor receptor gene and disparity in …


CJ Petry, KK Ong, DL Wingate, J Brown, CD … - Growth Hormone & IGF Research, 2005 - Elsevier
Results: The IGF2R gly1619arg genotype was not associated with any measure of
size at birth, but A/A homozygotes grew more slowly, as determined by their
change in height standard deviation scores (SDS) over the first three years ...
Cited by 14 - Related articles - All 3 versions

Replication of IGF2-INS-TH* 5 haplotype effect on obesity in older men and study of …


S Rodríguez, TR Gaunt, E Dennison, X Chen, … - European Journal of Human Genetics, 2005 - nature.com
Interindividual variation of the IGF2-INS-TH region influences risk of a variety
of diseases and complex traits. Previous studies identified a haplotype
(designated IGF2-INS-TH * 5 and tagged by allele A of IGF2 ApaI, allele 9 ...
Cited by 11 - Related articles - BL Direct - All 5 versions

Associations of adiposity from childhood into adulthood with insulin resistance and the …

- endojournals.org
RM Martin, JMP Holly, G Davey Smith, D … - Journal of Clinical Endocrinology & Metabolism, 2006 - Endocrine Soc
Context: One metabolic pathway through which adiposity influences disease risk
may be via alterations in insulin and IGF metabolism. ... Objective: Our
objective was to investigate associations of adiposity at different stages ...
Cited by 9 - Related articles - BL Direct - All 4 versions

[CITATION] The insulin-like growth factor system and diabetes-an overview


A Heald, R Stephens, JM Gibson - DIABETIC MEDICINE-CHICHESTER-, 2006 - interscience.wiley.com
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Cited by 9 - Related articles - BL Direct - All 4 versions

Polymorphisms in IGF-binding protein 1 are associated with impaired renal function in type …

- diabetesjournals.org
RH Stephens, P McElduff, AH Heald, JP New, … - Diabetes, 2005 - Am Diabetes Assoc
The dysregulation of the IGF system has been implicated in the pathogenesis of
obesity, diabetes, and diabetes complications such as nephropathy, but little is
known about the genomics of the IGF system in health and disease. We ...
Cited by 8 - Related articles - BL Direct - All 5 versions

Evidence for distinct effects of GH and IGF-I in the metabolic syndrome


P Maison, B Balkau, JC Souberbielle, P Cunin, … - Diabetic Medicine, 2007 - interscience.wiley.com
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display style sheets. In this case, although the visual presentation will be
degraded, the site should continue to be functional. We recommend using the ...
Cited by 8 - Related articles - BL Direct - All 3 versions


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