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Scholar Results 1 - 10 of about 34 citing Peppa: Fetal or neonatal low-glycotoxin environment prevents autoimmune diabetes in NOD mice. (0.12 sec) 

Advanced glycoxidation end products in commonly consumed foods


T Goldberg, W Cai, M Peppa, V Dardaine, BS … - Journal of the American …, 2004 - Elsevier
Foods of the fat group showed the highest amount of AGE content with a mean of 100±19
kU/g. High values were also observed for the meat and meat-substitute group, 43±7 kU/g. The
carbohydrate group contained the lowest values of AGEs, 3.4±1.8 kU/g. The amount of ...
Cited by 120 - Related articles - All 12 versions

Diet-derived advanced glycation end products are major contributors to the body's …


J Uribarri, W Cai, O Sandu, M Peppa, T … - ANNALS-NEW …, 2005 - interscience.wiley.com
Abstract: Advanced glycation end products (AGEs) are a heterogeneous group of compounds
that form continuously in the body. Their rate of endogenous formation is markedly increased
in diabetes mellitus, a condition in which AGEs play a major pathological role. It is also ...
Cited by 60 - Related articles - BL Direct - All 5 versions

Advanced glycation in health and disease: role of the modern environment


H Vlassara - ANNALS-NEW YORK ACADEMY OF SCIENCES, 2005 - interscience.wiley.com
Abstract: It is believed that intracellular and extracellular advanced glycation (AGEs) or lipoxidation
end products (ALEs), together with dysregulated glucose and lipid metabolism, are important
contributors to oxidant or carbonyl stress, enhanced cellular redox-sensitive transcription ...
Cited by 58 - Related articles - BL Direct - All 5 versions

Blockade of late stages of autoimmune diabetes by inhibition of the receptor for …

- jimmunol.org
Y Chen, SSD Yan, J Colgan, HP Zhang, J … - The Journal of …, 2004 - Am Assoc Immnol
Ligation of the receptor for advanced glycation end products (RAGE) occurs during
inflammation. Engagement of RAGE results in enhanced expression of addressins and it is
therefore, not surprising that previous studies have shown a role of RAGE/ligand ...
Cited by 54 - Related articles - BL Direct - All 5 versions

Adverse effects of dietary glycotoxins on wound healing in genetically diabetic …

- diabetesjournals.org
M Peppa, H Brem, P Ehrlich, JG Zhang, W Cai, Z Li, A … - Diabetes, 2003 - Am Diabetes Assoc
Advanced glycoxidation end products (AGEs) are implicated in delayed diabetic wound
healing. To test the role of diet-derived AGE on the rate of wound healing, we placed female
db/db (+/+) (n = 55, 12 weeks old) and age-matched control db/db (+/−) mice (n = 45) on ...
Cited by 50 - Related articles - BL Direct - All 4 versions

Insulin Resistance and Type 2 Diabetes in High-Fat–Fed Mice Are Linked to High …

- diabetesjournals.org
O Sandu, K Song, W Cai, F Zheng, J Uribarri, H … - Diabetes, 2005 - Am Diabetes Assoc
Dietary advanced glycosylation end products (AGEs) have been linked to insulin resistance in
db/db (++) mice. To test whether dietary AGEs play a role in the progression of insulin resistance
in normal mice fed high-fat diets, normal C57/BL6 mice were randomly assigned to ...
Cited by 47 - Related articles - BL Direct - All 6 versions

The role of advanced glycation end products in the development of atherosclerosis


M Peppa, J Uribarri, H Vlassara - Current Diabetes Reports, 2004 - Springer
Introduction Cardiovascular disease (CVD) is the leading cause of morbidity and mortality not
only in the United States but also worldwide [1]. Atherosclerosis constitutes the main pathologic
substrate of CVD, and through progressive thickening of the intima and plaque formation ...
Cited by 47 - Related articles - BL Direct - All 2 versions

Diabetes and advanced glycoxidation end products

- diabetesjournals.org
AG Huebschmann, JG Regensteiner, H Vlassara, … - Diabetes Care, 2006 - Am Diabetes Assoc
The morbidity caused by diabetes has traditionally been classified into macro- and microvascular
complications. Although macrovascular complications have received greater attention, microvascular
complications are unique to diabetes, and hyperglycemia contributes to their ...
Cited by 41 - Related articles - All 6 versions

Circulating glycotoxins and dietary advanced glycation endproducts: two links to …

- nih.gov
J Uribarri, W Cai, M Peppa, S Goodman, L … - … of Gerontology Series …, 2007 - Geron Soc America
Background. Oxidative stress (OS) and inflammatory mediators increase with aging. The levels
of advanced glycation endproducts (AGEs), prooxidant factors linked to chronic diseases such
as diabetes, cardiovascular disease, and renal disease, also increase with aging. AGEs ...
Cited by 36 - Related articles - BL Direct - All 5 versions

Glycoxidation and diabetic complications: modern lessons and a warning?


H Vlassara, J Uribarri - Reviews in Endocrine & Metabolic Disorders, 2004 - Springer
Diabetes and its complications represent an increasing medical problem worldwide [1]. Chronic
hyperglycemia leads to these complications through several intracellular mechanisms including
increased polyol pathway flow, ac- tivation of protein kinase C activity, increased ...
Cited by 28 - Related articles - BL Direct - All 3 versions


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