SB Jørgensen, B Viollet, F Andreelli, C Frøsig, JB … - Journal of Biological …, 2004 - ASBMB We investigated the importance of the two catalytic α-isoforms of the 5′-AMP-activated protein
kinase (AMPK) in 5-aminoimidazole-4-carboxamide-1-β-4-ribofuranoside (AICAR) and
contraction-induced glucose uptake in skeletal muscle. Incubated soleus and EDL ... Cited by 190 - Related articles - BL Direct - All 4 versions
- ►endojournals.org NB Ruderman, AK Saha, EW Kraegen - Endocrinology, 2003 - Endocrine Soc An increasing body of evidence has linked AMP-activated protein kinase (AMPK) and malonyl
coenzyme A (CoA) to the regulation of energy balance. Thus, factors that activate AMPK and
decrease the concentration of malonyl CoA in peripheral tissues, such as exercise, ... Cited by 116 - Related articles - BL Direct - All 7 versions
AK Saha, PR Avilucea, JM Ye, MM Assifi, EW … - … and Biophysical Research …, 2004 - Elsevier Thiazolidinediones have been shown to activate AMP-activated protein kinase activity in cultured
cells. Whether they have a similar effect in vivo and if so whether it is physiologically relevant
is not known. To assess these questions, we examined the effects of pioglitazone, ... Cited by 102 - Related articles - All 4 versions
JY Altarejos, M Taniguchi, AS Clanachan, GD … - Journal of Biological …, 2005 - ASBMB During myocardial ischemia, activation of 5'-AMP-activated protein kinase (AMPK) leads to the
stimulation of glycolysis and fatty acid oxidation. Together these metabolic changes contribute
to cardiac dysfunction. Although AMPK signaling in the ischemic heart is well ... Cited by 65 - Related articles - All 7 versions
SB Jørgensen, JN Nielsen, JB Birk, GS Olsen, B Viollet, … - Diabetes, 2004 - Am Diabetes Assoc The 5'AMP-activated protein kinase (AMPK) is a potential antidiabetic drug target. Here we show
that the pharmacological activation of AMPK by 5-aminoimidazole-1-ß-4-carboxamide ribofuranoside
(AICAR) leads to inactivation of glycogen synthase (GS) and phosphorylation of GS at Ser ... Cited by 63 - Related articles - BL Direct - All 4 versions
H Clark, D Carling, D Saggerson - European Journal of …, 2004 - interscience.wiley.com Rat hearts were perfused for 1 h with 5 mm glucose with or without palmitate or oleate at concentrations
characteristic of the fasting state. The inclusion of fatty acids resulted in increased activities of
the α-1 or the α-2 isoforms of AMP-activated protein kinase (AMPK), increased ... Cited by 54 - Related articles - BL Direct - All 7 versions
- ►endojournals.org C Bouche, S Serdy, CR Kahn, AB Goldfine - Endocrine reviews, 2004 - Endocrine Soc Type 2 diabetes is a complex disorder with diminished insulin secretion and insulin action contributing
to the hyperglycemia and wide range of metabolic defects that underlie the disease. The contribution
of glucose metabolic pathways per se in the pathogenesis of the disease remains ... Cited by 53 - Related articles - BL Direct - All 6 versions
SB Jørgensen, EA Richter, JFP … - The Journal of …, 2006 - Physiological Soc The 5′-AMP-activated protein kinase (AMPK) is a potent regulator of skeletal muscle metabolism
and gene expression. AMPK is activated both in response to in vivo exercise and ex vivo
contraction. AMPK is therefore believed to be an important signalling molecule in ... Cited by 47 - Related articles - BL Direct - All 9 versions
Y Liu, Q Wan, Q Guan, L Gao, J Zhao - Biochemical and Biophysical Research …, 2006 - Elsevier Total 40 male Wistar rats were randomly divided into three groups and received either a rat maintenance
diet (Control group) or an isocaloric rich-fat diet (HF group and MET group) for five months. Metformin
was administered orally with the daily dose of 300 mg in MET group during the last month ... Cited by 41 - Related articles - All 5 versions
- ►physiology.org EW Kraegen, AK Saha, E Preston, D Wilks … - American Journal of …, 2006 - Am Physiological Soc Glucose infusion in rats for 1–4 days results in insulin resistance and increased triglyceride, whole
tissue long-chain fatty acyl-CoA (LCA-CoA), and malonyl-CoA content in red skeletal
muscle. Despite this, the relation between these alterations and the onset of insulin ... Cited by 32 - Related articles - BL Direct - All 4 versions
