- ►alfediam.org [PDF] C Postic, R Dentin, J Girard - Diabetes and Metabolism, 2004 - Elsevier The liver plays a unique role in controlling carbohydrate metabolism by
maintaining glucose concentrations in a normal range over both short and long
periods of times. In type 2 diabetes, alterations in hepatic glucose ... Cited by 47 - Related articles - All 4 versions
K Chakravarty, H Cassuto, L Reshef, RW … - Critical reviews in biochemistry and molecular biology, 2005 - informahealthcare.com The cytosolic form of PEPCK (PEPCK-C) is generally considered to be the
pace-setting enzyme in hepatic and renal gluconeogenesis (Rognstad, 1979). In
this role, alterations in PEPCK-C mRNA in the liver in response to a wide ... Cited by 46 - Related articles - All 9 versions
- ►jbc.org SC Burgess, N Hausler, M Merritt, FMH … - Journal of Biological Chemistry, 2004 - ASBMB Liver-specific phosphoenolpyruvate carboxykinase (PEPCK) null mice, when fasted,
maintain normal whole body glucose kinetics but develop dramatic hepatic
steatosis. To identify the abnormalities of hepatic energy generation that ... Cited by 32 - Related articles - BL Direct - All 9 versions
- ►ahajournals.org RD Rudic, P McNamara, D Reilly, T Grosser, … - Circulation, 2005 - Am Heart Assoc Methods and Results— Aortae from mice were harvested at 4-hour intervals for 2
circadian cycles (48 hours). Gene expression was assessed by expression
profiling and subjected to a gene ontology bioinformatics analysis. Three ... Cited by 28 - Related articles - All 16 versions
G Mithieux, F Rajas, A Gautier-Stein - Journal of Biological Chemistry, 2004 - ASBMB Glucose 6-phosphatase (EC 3.1.3.9, Glc-6-Pase) 1 is a crucial enzyme in the
control of glucose homeostasis. It catalyzes the last biochemical reaction of
gluconeogenesis and glycogenolysis, ie the hydrolysis of glucose ... Cited by 25 - Related articles - BL Direct - All 4 versions
- ►jbc.org SC Burgess, TC Leone, AR Wende, MA Croce, … - Journal of Biological Chemistry, 2006 - ASBMB The peroxisome proliferator-activated receptor (PPAR ) coactivator 1 (PGC-1 ) is
a highly inducible transcriptional coactivator implicated in the coordinate
regulation of genes encoding enzymes involved in hepatic fatty acid ... Cited by 23 - Related articles - BL Direct - All 10 versions
B Cariou, K van Harmelen, D Duran-Sandoval, T … - FEBS letters, 2005 - Elsevier The farnesoid X receptor (FXR) has been suggested to play a role in
gluconeogenesis. To determine whether FXR modulates the response to fasting in
vivo, FXR-deficient (FXR −/− ) and wild-type mice were submitted to ... Cited by 22 - Related articles - All 4 versions
- ►nih.gov M Chen, O Gavrilova, WQ Zhao, A Nguyen, J … - Journal of Clinical Investigation, 2005 - Am Soc Clin Investig The G protein G s α is essential for hormone-stimulated cAMP generation and is
an important metabolic regulator. We investigated the role of liver G s
-signaling pathways by developing mice with liver-specific G s α ... Cited by 20 - Related articles - BL Direct - All 10 versions
B Cariou, D Duran-Sandoval, F Kuipers, B … - Endocrinology, 2005 - Endocrine Soc Bile acids are liver-synthesized cholesterol derivatives that are postprandially
released into the small intestine, where they act as detergents to promote fat
absorption. Conversion to bile acids also represents the major route for ... Cited by 18 - Related articles - All 5 versions
