Y Dor, J Brown, OI Martinez, DA Melton - Nature, 2004 - molecool.wustl.edu How tissues generate and maintain the correct number of cells is a fundamental
problem in biology. In principle, tissue turnover can occur by the
differentiation of stem cells, as is well documented for blood, skin and ... Cited by 792 - Related articles - View as HTML - BL Direct - All 26 versions
- ►physiology.org L Bouwens, I Rooman - Physiological reviews, 2005 - Am Physiological Soc Beta-cell mass regulation represents a critical issue for understanding
diabetes, a disease characterized by a near-absolute (type 1) or relative (type
2) deficiency in the number of pancreatic beta cells. The number of islet ... Cited by 118 - Related articles - BL Direct - All 6 versions
S Bonner-Weir, E Toschi, A Inada, P Reitz, … - Pediatric diabetes, 2004 - interscience.wiley.com It is also possible that your web browser is not configured or not able to
display style sheets. In this case, although the visual presentation will be
degraded, the site should continue to be functional. We recommend using the ... Cited by 101 - Related articles - BL Direct - All 3 versions
- ►diabetesjournals.org M Teta, SY Long, LM Wartschow, MM Rankin, … - Diabetes, 2005 - Am Diabetes Assoc Although many signaling pathways have been shown to promote ß-cell growth,
surprisingly little is known about the normal life cycle of preexisting ß-cells
or the signaling pathways required for ß-cell survival. Adult ß-cells ... Cited by 99 - Related articles - BL Direct - All 5 versions
- ►upenn.edu [PDF] M Teta, MM Rankin, SY Long, GM Stein, JA … - Developmental cell, 2007 - Elsevier Cellular progenitors remain poorly characterized in many adult tissues, limited
in part by the lack of unbiased techniques to identify progenitors and their
progeny. To address this fundamental problem, we developed a novel DNA ... Cited by 89 - Related articles - All 12 versions
Y Sun, M Asnicar, PK Saha, L Chan, RG … - Cell metabolism, 2006 - Elsevier Ghrelin and leptin are suggested to regulate energy homeostasis as mutual
antagonists on hypothalamic neurons that regulate feeding behavior. We employed
reverse genetics to investigate the interplay between ghrelin and leptin. ... Cited by 71 - Related articles - All 11 versions
- ►physiology.org F Capozza, TP Combs, AW Cohen, YR Cho, SY … - American Journal of Physiology- Cell Physiology, 2005 - Am Physiological Soc Caveolin-3 (Cav-3) is expressed predominantly in skeletal muscle fibers, where
it drives caveolae formation at the muscle cell's plasma membrane. In vitro
studies have suggested that Cav-3 may play a positive role in insulin ... Cited by 27 - Related articles - All 4 versions
OD Madsen - Apmis, 2005 - interscience.wiley.com Diabetes mellitus types 1 and 2 are characterized by absolute versus relative
lack of insulin-producing β cells, respectively. Reconstitution of a functional
β-cell mass by cell therapy – using organ donor islets of Langerhans – ... Cited by 27 - Related articles - BL Direct - All 6 versions
- ►endojournals.org SM Clee, AD Attie - Endocrine reviews, 2007 - Endocrine Soc Inbred mouse strains provide genetic diversity comparable to that of the human
population. Like humans, mice have a wide range of diabetes-related phenotypes.
The inbred mouse strains differ in the response of their critical ... Cited by 29 - Related articles - BL Direct - All 4 versions
RL Hull, K Kodama, KM Utzschneider, DB … - Diabetologia, 2005 - Springer Abstract Aims/hypothesis: Increased dietary fat intake is associated with
obesity and insulin resistance, but studies have shown that the subsequent
increase in insulin release is not appropriate for this obesity-induced ... Cited by 23 - Related articles - BL Direct - All 3 versions
