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Scholar Results 1 - 10 of about 104 citing Noguchi: PDX-1 protein containing its own antennapedia-like protein transduction domain can.... (0.14 sec) 

Delivery of bioactive molecules into the cell: the Trojan horse approach


GPH Dietz, M Bδhr - Molecular and Cellular Neuroscience, 2004 - Elsevier
In recent years, vast amounts of data on the mechanisms of neural de- and
regeneration have accumulated. However, only in disproportionally few cases has
this led to efficient therapies for human patients. Part of the problem is ...
Cited by 197 - Related articles - All 3 versions

Possible novel therapy for diabetes with cell-permeable JNK-inhibitory peptide


H Kaneto, Y Nakatani, T Miyatsuka, D … - Nature medicine, 2004 - nature.com
The JNK pathway is known to be activated in several tissues in the diabetic
state, and is possibly involved in the development of insulin resistance and
suppression of insulin biosynthesis. Here we show a potential new therapy ...
Cited by 166 - Related articles - BL Direct - All 4 versions

The pancreatic ductal epithelium serves as a potential pool of progenitor cells


S Bonner-Weir, E Toschi, A Inada, P Reitz, … - Pediatric diabetes, 2004 - interscience.wiley.com
It is also possible that your web browser is not configured or not able to
display style sheets. In this case, although the visual presentation will be
degraded, the site should continue to be functional. We recommend using the ...
Cited by 100 - Related articles - BL Direct - All 3 versions

Effects of dietary fatty acids on insulin sensitivity and secretion


M Manco, M Calvani, G Mingrone - Diabetes Obesity and Metabolism, 2004 - interscience.wiley.com
Globalization and global market have contributed to increased consumption of
high‐fat, energy‐dense diets, particularly rich in saturated fatty acids(
SFAs). Polyunsaturated fatty acids (PUFAs) regulate fuel partitioning ...
Cited by 63 - Related articles - BL Direct - All 3 versions

[PDF] Protein transduction technology: a novel therapeutic perspective


H Noguchi, S Matsumoto - Acta Medica Okayama, 2006 - lib.okayama-u.ac.jp
The direct intracellular delivery of proteins has, until recently, been
difficult to achieve, due primar- ily to the bioavailability barrier of the
plasma membrane. During the past 15 years, a variety of peptides called ...
Cited by 49 - Related articles - View as HTML - BL Direct - All 8 versions

PDX-1/VP16 fusion protein, together with NeuroD or Ngn3, markedly induces insulin gene …

- diabetesjournals.org
H Kaneto, Y Nakatani, T Miyatsuka, T … - Diabetes, 2005 - Am Diabetes Assoc
Diabetes is the most prevalent and serious metabolic disease, and the number of
diabetic patients worldwide is increasing. The reduction of insulin biosynthesis
in pancreatic β-cells is closely associated with the onset and progression ...
Cited by 50 - Related articles - All 6 versions

Involvement of oxidative stress in the pathogenesis of diabetes


H Kaneto, N Katakami, D Kawamori, T … - Antioxidants & redox signaling, 2007 - liebertonline.com
F AILURE OF PANCREATIC cells is the common characteris- tic of type 1 and type 2
diabetes. Type 1 diabetes melli- tus is induced by destruction of pancreatic
cells, which is mediated by an autoimmune mechanism and the consequent ...
Cited by 47 - Related articles - BL Direct - All 4 versions

Oxidative stress, ER stress, and the JNK pathway in type 2 diabetes


H Kaneto, T Matsuoka, Y Nakatani, D … - Journal of Molecular Medicine, 2005 - Springer
Page 1. J Mol Med (2005) 83: 429–439 DOI 10.1007/s00109-005-0640-x REVIEW Hideaki
Kaneto . Taka-aki Matsuoka . Yoshihisa Nakatani . Dan Kawamori . ...
Cited by 46 - Related articles - All 3 versions

TAT-mediated neurogenin 3 protein transduction stimulates pancreatic endocrine …

- diabetesjournals.org
J Domínguez-Bendala, D Klein, M Ribeiro, C … - Diabetes, 2005 - Am Diabetes Assoc
Stem cell technologies hold great potential for the treatment of type 1
diabetes, provided that functional transplantable ß-cells can be selectively
generated in an efficient manner. Such a process should recapitulate, at ...
Cited by 43 - Related articles - All 5 versions

Cellular manipulation of human embryonic stem cells by TAT-PDX1 protein transduction


YD Kwon, SK Oh, HS Kim, SY Ku, SH Kim, YM … - Molecular Therapy, 2005 - Elsevier
Human embryonic stem cells (hESCs) are an in vitro model system for the study of
human early development and a potential source for cell-based therapies. An
efficient strategy for cellular manipulation of hESCs may be highly ...
Cited by 42 - Related articles - All 3 versions


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