- ►diabetesjournals.org AJM Boulton, RA Malik, JC Arezzo, JM … - Diabetes Care, 2004 - Am Diabetes Assoc The neuropathies are among the most common of the long-term complications of
diabetes, affecting up to 50% of patients (1–4). Their clinical features vary
immensely, and patients may present to a wide spectrum of specialties, from ... Cited by 226 - Related articles - BL Direct - All 6 versions
AAF Sima, W Zhang, ZG Li, Y Murakawa, CR … - Diabetes, 2004 - Am Diabetes Assoc To explore the molecular abnormalities underlying the degeneration of the node
of Ranvier, a characteristic aberration of type 1 diabetic neuropathy, we
examined in type 1 BB/Wor and type 2 BBZDR/Wor rats changes in expression ... Cited by 41 - Related articles - BL Direct - All 4 versions
K Ekberg, T Brismar, BL Johansson, P … - Diabetes Care, 2007 - Am Diabetes Assoc RESULTS—The age of the 139 patients who completed the protocol was 44.2 ± 0.6
(mean ± SE) years and their duration of diabetes was 30.6 ± 0.8 years.
Clinical neurological impairment (NIA) (score >7 points) of the lower ... Cited by 37 - Related articles - BL Direct - All 5 versions
- ►physiology.org MJ Stevens, W Zhang, F Li, AAF Sima - American Journal of Physiology- Endocrinology And …, 2004 - Am Physiological Soc Oxidative stress and neurovascular dysfunction have emerged as contributing
factors to the development of experimental diabetic neuropathy (EDN) in
streptozotocin-diabetic rodents. Additionally, depletion of C-peptide has ... Cited by 33 - Related articles - All 4 versions
J Wahren - Clinical physiology and functional imaging, 2004 - interscience.wiley.com In contrast to earlier views, new data indicate that proinsulin C-peptide exerts
important physiological effects and shows the characteristics of an endogenous
peptide hormone. C-peptide in nanomolar concentrations binds specifically ... Cited by 30 - Related articles - BL Direct - All 5 versions
- ►physiology.org BL Johansson, J Wahren, J Pernow - American Journal of Physiology- Endocrinology And …, 2003 - Am Physiological Soc Proinsulin C-peptide has been shown to increase muscle blood flow in type 1
diabetic patients. The underlying mechanism is not fully understood. The aim of
this study was to evaluate if the vasodilator effect of C-peptide is ... Cited by 26 - Related articles - BL Direct - All 4 versions
J Wahren, K Ekberg, H Jörnvall - Diabetologia, 2007 - Springer Page 1. FOR DEBATE C-peptide is a bioactive peptide J. Wahren & K. Ekberg
& H. Jörnvall Received: 8 June 2006 /Accepted: 24 October ... Cited by 28 - Related articles - BL Direct - All 4 versions
H Kamiya, W Zhang, K Ekberg, J Wahren, … - Diabetes, 2006 - Am Diabetes Assoc We examined the therapeutic effects of C-peptide on established nociceptive
neuropathy in type 1 diabetic BB/Wor rats. Nociceptive nerve function,
unmyelinated sural nerve fiber and dorsal root ganglion (DRG) cell ... Cited by 20 - Related articles - BL Direct - All 5 versions
RG Marques, MJ Fontaine, J Rogers - Pancreas, 2004 - journals.lww.com Objectives: During the past decade, numerous studies in both humans and animals
have demonstrated that C-peptide, although not influencing blood sugar control,
might play a role in preventing and potentially reversing some of the ... Cited by 16 - Related articles - BL Direct - All 2 versions