D Jay, H Hitomi, KK Griendling - Free Radical Biology and Medicine, 2006 - Elsevier Diabetes diagnoses are increasing at an alarming rate worldwide. The majority of
diabetes-related deaths arise from cardiovascular complications such as
myocardial infarction, stroke, and peripheral vascular disease. Oxidative ... Cited by 109 - Related articles - All 4 versions
- ►cardiovascres.org JL Mehta, J Chen, PL Hermonat, F Romeo, G … - Cardiovascular research, 2006 - cardiovascres.org LOX-1, a lectin-like 52-kD receptor for oxidized low-density lipoproteins
(ox-LDL), is present primarily on endothelial cells. This receptor is
upregulated by ox-LDL itself and by angiotensin II, endothelin, cytokines, ... Cited by 104 - Related articles - All 7 versions
KV Ramana, B Friedrich, S Srivastava, A … - Diabetes, 2004 - Am Diabetes Assoc Activation of the polyol pathway has been linked to the development of secondary
diabetic complications. However, the underlying molecular mechanisms remain
unclear. To probe the contribution of this pathway, we examined whether ... Cited by 61 - Related articles - BL Direct - All 4 versions
- ►ahajournals.org L Li, N Roumeliotis, T Sawamura, G Renier - Circulation research, 2004 - Am Heart Assoc C-reactive protein (CRP), a characteristic inflammatory marker, is a powerful
predictor of cardiovascular events. Recent data suggest that CRP may also
promote atherogenesis through inducing endothelial dysfunction. Lectin-like ... Cited by 59 - Related articles - BL Direct - All 7 versions
- ►shouxi.net K Fukuhara-Takaki, M Sakai, Y Sakamoto, M … - Journal of Biological Chemistry, 2005 - ASBMB In the early stage of atherosclerosis, macrophages take up chemically modified
low density lipoproteins (LDL) through the scavenger receptors, leading to foam
cell formation in atherosclerotic lesions. To get insight into a role of ... Cited by 49 - Related articles - All 5 versions
- ►hematologylibrary.org J Ehrchen, L Steinmuller, K Barczyk, K … - Blood, 2007 - bloodjournal.hematologylibrary.org Monocytes and macrophages may either promote or down-regulate inflammatory
reactions depending on their state of activation. The effects of glucocorticoids
(GCs), the most widely used immunosuppressive drugs, on monocytes are ... Cited by 36 - Related articles - BL Direct - All 3 versions
- ►endojournals.org E Pagnin, G Fadini, R de Toni, A Tiengo, L … - Journal of Clinical Endocrinology & Metabolism, 2005 - Endocrine Soc Oxidative stress plays a role in cardiovascular dysfunction. This is of interest
in diabetes, a clinical condition characterized by oxidative stress and
increased prevalence of cardiovascular disease. The role of p66 shc in ... Cited by 39 - Related articles - All 5 versions
H Adachi, M Tsujimoto - Progress in Lipid Research, 2006 - Elsevier In the past few decades, cDNAs for endothelial scavenger receptors that bind to
negatively charged molecules, particularly acetylated low density lipoproteins
(Ac-LDL), have been cloned by expression cloning using modified LDL as ... Cited by 34 - Related articles - All 2 versions
OI Stenina - Current pharmaceutical design, 2005 - ingentaconnect.com Abstract: Endothelial dysfunction is an early sign of diabetic vascular disease.
Due to their unique position at the border between blood and vascular tissue,
endothelial cells (EC) are the first vascular cells to sensor humoral ... Cited by 21 - Related articles - All 4 versions
N Ouslimani, M Mahrouf, J Peynet, D … - Metabolism, 2007 - Elsevier Beyond its antihyperglycemic action, the antidiabetic oral drug metformin
possesses antioxidant properties that may contribute to improve the
cardiovascular deleterious effects of the diabetic disease. We explored ... Cited by 17 - Related articles - All 9 versions
